Saturated fat and cardiovascular disease: Difference between revisions
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==Individual studies== |
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===Studies linking CVD to saturated fat=== |
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No randomized clinical trials of low-fat diets or low-saturated fat diets of sufficient duration have been carried out. The influence of varying saturated fatty acid intakes against a background of different individual lifestyles and genetic backgrounds should be the focus in future studies.<ref>{{cite journal |author=German JB, Dillard CJ |title=Saturated fats: what dietary intake? |journal=The American Journal of Clinical Nutrition |volume=80 |issue=3 |pages=550–9 |year=2004 |month=September |pmid=15321792 |url=http://www.ajcn.org/cgi/pmidlookup?view=long&pmid=15321792}}</ref> |
No randomized clinical trials of low-fat diets or low-saturated fat diets of sufficient duration have been carried out. The influence of varying saturated fatty acid intakes against a background of different individual lifestyles and genetic backgrounds should be the focus in future studies.<ref>{{cite journal |author=German JB, Dillard CJ |title=Saturated fats: what dietary intake? |journal=The American Journal of Clinical Nutrition |volume=80 |issue=3 |pages=550–9 |year=2004 |month=September |pmid=15321792 |url=http://www.ajcn.org/cgi/pmidlookup?view=long&pmid=15321792}}</ref> |
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==References== |
==References== |
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Revision as of 09:15, 24 January 2011
Whether Saturated Fat is a risk factor for Cardiovascular Disease (CVD) is a question with numerous views. Although there is a scientific consensus in the heart-health and medical communities that saturated fat is a risk factor for CVD, individual studies produce conflicting results and notable authors have prepared opposing viewpoints.
Heart-health organizations
Consumption of saturated fat is a risk factor for cardiovascular disease in the view of the Canadian Heart and Stroke Foundation,[1] the American Heart Association,[2] the British Heart Foundation,[3] the National Heart Foundation of Australia,[4] the National Heart Foundation of New Zealand [5] and the World Heart Federation.[6]
Medical establishments
The World Health Organization (WHO) has concluded that saturated fats negatively affect cholesterol profiles, predisposing individuals to heart disease, and recommends avoiding saturated fats in order to reduce the risk of a cardiovascular disease.[7][8]
Mayo Clinic highlighted oils that are high in saturated fats include coconut, palm oil and palm kernel oil. Those of lower amounts of saturated fats, and higher levels of unsaturated (preferably monounsaturated) fats like olive oil, peanut oil, canola oil, avocados, safflower, corn, sunflower, soy and cottonseed oils are generally healthier.[9]
Notable authors
Gary Taubes, a science writer specializing in controversy and three-time winner of the Science in Society Award of the National Association of Science Writers concludes Dietary fat, whether saturated or not, is not a cause of obesity, heart disease, or any other chronic disease of civilization.[10] Writing in Men's Health Magazine, Nina Teicholz proposed that intake of saturated fat is only correlated with heart disease, "not a clear, causal link." [11] Further, Mary Enig of The International Network of Cholesterol Skeptics asserts there is strong evidence for the cardiovascular benefits of saturated fats.[12]
Individual studies
Studies linking CVD to saturated fat
Some meta-analyses have found a significant relationship between saturated fat and serum cholesterol levels,[13] and serum cholesterol levels and cardiovascular disease,[14] yet 11 of the 15 studies that measured the relationship between saturated fat and coronary heart disease in this meta-analysis were adjusted for serum lipids or other dietary lipids. The remaining 4 studies found a significant relationship between saturated fat and coronary heart disease.[15] Furthermore, a positive relationship between saturated fat and fatal coronary heart disease was found despite an over-adjustment for serum lipids.[15]
It was found that substitution of the fat from one ounce of nuts for equivalent energy from saturated fat was associated with a 45% reduction in risk of coronary heart disease.[16]
Studies not linking CVD to saturated fat
In 2010, a meta-analysis of prospective cohort studies supported by the National Dairy Council including 348,000 subjects found no statistically significant relationship between cardiovascular disease and dietary saturated fat.[17][18]
A scientific conference hosted by the University of Reading (UK) and organized and facilitated by the International Dairy Federation’s Standing Committee on Nutrition and Health found that despite the contribution of dairy products to the saturated fatty acid intake of the diet, there was not clear evidence that dairy food consumption is consistently associated with a higher risk of CVD.[19]
In 2009, a systematic review of prospective cohort studies or randomized trials concluded that there was "insufficient evidence of association" between intake of saturated fatty acids and coronary heart disease, and pointed to strong evidence for protective factors such as vegetables and a Mediterranean diet and harmful factors such as trans fats and foods with a high glycemic index.[20] However, this systematic review included studies that adjusted for serum lipids or other dietary lipids which were also included in the previously described meta-analysis.[17][20]
A study published in the Lancet in 1994 found that how long-term dietary intake of essential fatty acids affects the fatty-acid content of aortic plaques is not clear.[21]
An evaluation of data from Harvard Nurses' Health Study found that "diets lower in carbohydrate and higher in protein and fat are not associated with increased risk of coronary heart disease in women. When vegetable sources of fat and protein are chosen, these diets may moderately reduce the risk of coronary heart disease."[22]
Pacific island populations who obtain 30-60% of their total caloric intake from fully saturated coconut fat have low rates of cardiovascular disease.[23]
Studies of dietary customs of certain ethnic groups may be confounded by other cultural customs. For example, Fulani of northern Nigeria get around 25% of energy from saturated fat, yet their lipid profile is indicative of a low risk of cardiovascular disease. However, this finding may be due to their high activity level and their low total energy intake.[24] Saturated fat intakes may be monitored more closely than were total fat intakes, therefore ignoring the possibility that simply a larger fat intake may lead to a higher risk of coronary diseases. It also suggests that other parameters may be overlooked, such as carbohydrates intakes.[25]
No randomized clinical trials of low-fat diets or low-saturated fat diets of sufficient duration have been carried out. The influence of varying saturated fatty acid intakes against a background of different individual lifestyles and genetic backgrounds should be the focus in future studies.[26]
References
- ^ "Dietary fats, oils and cholesterol". Retrieved 2010-12-22.
- ^ "Know Your Fats". Retrieved 2010-12-22.
- ^ "Saturated Fat". Retrieved 2010-12-22.
- ^ "'Reduce saturated fat' urges Heart Foundation after major review" (PDF). Retrieved 2010-12-22.
- ^ "Dietary Fats: An Evidence-Based Nutrition Statement from the National Heart Foundation of New Zealand's Nutrition Advisory Committee" (PDF). March 1999. Retrieved 2010-12-22.
{{cite web}}:|first=missing|last=(help); Text "last - Seddon MB. ChB. MPH." ignored (help) - ^ "Cardiovascular Disease Risk Factors". Retrieved 2010-12-23.
- ^ World Health Organization Risk factor: lipids
- ^ World Health Organization Prevention: personal choices and actions
- ^ Dietary fats: Know which types to choose Mayo Clinic website
- ^ Taubes, Gary (2007). Good Calories, Bad Calories: Google Book Preview, Page 454. Knopf. p. 609. Retrieved 2011-01-02.
- ^ men's health magazine "what if bad fat is actually good for you By Nina Teicholz, Photographs by Nikolai Golovanoff, Posted Date: October 10, 2007
- ^ The Truth About Saturated Fats by Mary Enig, PhD, and Sally Fallon
- ^ Clarke, R; Frost, C; Collins, R; Appleby, P; Peto, R (1997). "Dietary lipids and blood cholesterol: quantitative meta-analysis of metabolic ward studies". BMJ (Clinical research ed.). 314 (7074): 112–7. PMC 2125600. PMID 9006469.
- ^ Lewington S, Whitlock G, Clarke R, Sherliker P, Emberson J, Halsey J, Qizilbash N, Peto R, Collins R (2007). "Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths". Lancet. 370 (9602): 1829–39. doi:10.1016/S0140-6736(07)61778-4. PMID 18061058.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ a b Stamler J (2010). "Diet-heart: a problematic revisit" (PDF). The American Journal of Clinical Nutrition. 91 (3): 497–99. doi:10.3945/ajcn.2010.29216. PMID 20130097.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ Hu FB, Stampfer MJ (1999). "Nut consumption and risk of coronary heart disease: a review of epidemiologic evidence". Current Atherosclerosis Reports. 1 (3): 204–209. doi:10.1007/s11883-999-0033-7. PMID 11122711.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ a b Siri-Tarino PW, Sun Q, Hu FB, Krauss RM (2010). "Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease". The American Journal of Clinical Nutrition. 91 (3): 535–46. doi:10.3945/ajcn.2009.27725. PMC 2824152. PMID 20071648.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ Siri-Tarino PW, Sun Q, Hu FB, Krauss RM (2010). "Saturated fat, carbohydrate, and cardiovascular disease". The American Journal of Clinical Nutrition. 91 (3): 502–9. doi:10.3945/ajcn.2008.26285. PMC 2824150. PMID 20089734.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ German JB, Gibson RA, Krauss RM; et al. (2009). "A reappraisal of the impact of dairy foods and milk fat on cardiovascular disease risk". European Journal of Nutrition. 48 (4): 191–203. doi:10.1007/s00394-009-0002-5. PMC 2695872. PMID 19259609.
{{cite journal}}: Explicit use of et al. in:|author=(help); Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ a b Mente A, de Koning L, Shannon HS, Anand SS (2009). "A systematic review of the evidence supporting a causal link between dietary factors and coronary heart disease". Arch. Intern. Med. 169 (7): 659–69. doi:10.1001/archinternmed.2009.38. PMID 19364995.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) Free full-text - ^ FELTON C. V. ; CROOK D. ; DAVIES M. J. ; OLIVER M. F. ; Lancet ISSN 0140-6736 CODEN LANCAO Source / Source 1994, vol. 344, no8931, pp. 1195-1196 (9 ref.)
- ^ Halton TL, Willett WC, Liu S; et al. (2006). "Low-carbohydrate-diet score and the risk of coronary heart disease in women". The New England Journal of Medicine. 355 (19): 1991–2002. doi:10.1056/NEJMoa055317. PMID 17093250.
{{cite journal}}: Explicit use of et al. in:|author=(help); Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ Prior IA, Davidson F, Salmond CE, Czochanska Z (1981). "Cholesterol, coconuts, and diet on Polynesian atolls: a natural experiment: the Pukapuka and Tokelau island studies". The American Journal of Clinical Nutrition. 34 (8): 1552–61. PMID 7270479.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ Glew RH, Williams M, Conn CA; et al. (2001). "Cardiovascular disease risk factors and diet of Fulani pastoralists of northern Nigeria". The American Journal of Clinical Nutrition. 74 (6): 730–6. PMID 11722953.
{{cite journal}}: Explicit use of et al. in:|author=(help); Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ Knopp RH, Retzlaff BM (2004). "Saturated fat prevents coronary artery disease? An American paradox". The American Journal of Clinical Nutrition. 80 (5): 1102–3. PMID 15531654.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ German JB, Dillard CJ (2004). "Saturated fats: what dietary intake?". The American Journal of Clinical Nutrition. 80 (3): 550–9. PMID 15321792.
{{cite journal}}: Unknown parameter|month=ignored (help)