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Article in progress: Added section on bioengineered urethral research
Bioengineered urethral research: added reference to the female urethra
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== Bioengineered urethral research ==
== Bioengineered urethral research ==


Dr. Anthony Atala, director of the Wake Forest Institute of Regenerative Medicine has pioneered the first laboratory grown human urethra(s) which were successfully transplanted into humans. I am attempting to contact him for an update of the progress of efficacy trials, and will post the reply on this page when received. This, in my opinion, offers the best hope for revision and repair of severely compromised male human urethras. [[User:PA MD0351XXE|PA MD0351XXE]] ([[User talk:PA MD0351XXE|talk]]) 05:23, 28 June 2012 (UTC)
Dr. Anthony Atala, director of the Wake Forest Institute of Regenerative Medicine has pioneered the first laboratory grown human urethra(s) which were successfully transplanted into humans. I am attempting to contact him for an update of the progress of efficacy trials, and will post the reply on this page when received. This, in my opinion, offers the best hope for revision and repair for the severely compromised male human urethra, and I expect similar findings in with female recipients . [[User:PA MD0351XXE|PA MD0351XXE]] ([[User talk:PA MD0351XXE|talk]]) 05:23, 28 June 2012 (UTC)

Revision as of 05:25, 28 June 2012

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Added

Added a few lines on the causes. Pain on micturition is not, in my experience, a common presenting feature of urethral strictures. Jfbcubed 13:35, 22 July 2006 (UTC)[reply]

Merge proposal from Meatal stenosis

I discovered that the meatal stenosis article claims it is synonymous with urethral stricture. Furthermore, the ICD-9 and DiseaseDB codes are similar, if not identical. I propose merging the former into this article (since this article is in the infobox at the bottom) and converting the former into a redirect to this article. --Joe Sewell (talk) 20:57, 28 January 2009 (UTC)[reply]

I just confirmed that the ICD-9 code here is more specific than the one at urethral stricture. Furthermore, the two MeSH specifiers lead to the same page through different paths. --Joe Sewell (talk) 21:02, 28 January 2009 (UTC)[reply]
As a retiring Urologist, I would hesitate to include meatal stenosis within the definition of urethral stricture/stricture disease for two reasons (although, technically meatal stenosis is a stricture):
1. The surgical resolution for meatal stenosis, meatotomy, is an easily accomplished, usually permanent repair to a more superficial problem than the more complex treatments required for resolution of bulbar urethral stricture.
2. Despite the best efforts of most physicians, bulbar urethral strictures are at best, difficult to treat, often requiring a lifetime of surgery and follow-up treatments. The surgery required is (often) very complex in circumstances where (even recurrent) urethral dilatation alone fails to provide relief from the disorder for more than 6 months. Toward the end of my career, I began sending patients initially encountering the disorder to counseling to help cope with this life-long condition.
Mr. Sewell was prudent in his thinking.75.97.65.10 (talk) 23:05, 19 March 2011 (UTC)[reply]
Do not merge. On the urologist's evidence, the two conditions are of very different severity and difficulty of treatment. It would be best to:
  1. Keep the articles separate, and
  2. Clarify that they are distinct diseases with different causes, treatments and prognoses. yoyo (talk) 17:24, 23 February 2012 (UTC)[reply]
As the merge notice has already been removed from the Meatal stenosis page, I will remove also it from this one. yoyo (talk)

Recommend defining Urethral stricture into two categories, Urethral Stricture - Male, and Urethral Stricture - Female

The reasoning behind this is the fact that the anatomy of the female urethra is so vastly different from that of the male, which includes the penis, urethra, the bulbar urethra, the ejaculatory duct, the urinary sphincter, and the prostate (with its musculature). The female urethra is essentially composed of the urethra, the urinary sphincter, and the urinary meatus.

The diagnostic and treatment regimen for female stricture disease is also vastly different from that of the male.75.97.65.10 (talk) 18:48, 22 March 2011 (UTC)[reply]

I believe a good case has been made for such a division, so would support it. One of the failings of the present articles on urethral disease and treatment is an often tacit assumption either as to the patient's sex, or of sufficient medical knowledge to determine the patient's sex from the anatomical terms used. Separating the two discussions would make it less likely that this problem would recur. yoyo (talk) 17:16, 23 February 2012 (UTC)[reply]

Ayurvedic Treatment of Urethral Stricture Disease

Recently, a reference to an Ayurvedic treatment of strictures known as Uttarbasti was posted within the linked references section. Although the link appears to be commercial, and of pecuniary interest to the owner of the site, two of my patients have elected to undergo the urethral instillation of certain Ayurvedic oils and medications into the urethra for treatment of their disorder, and reported favorable results (although not to the point of being considered a "cure"). They each had an approximate 50% improvement in their Uroflowmetry, and have, as yet, required no additional prescriptions for antibiotics for UTI's. (time-frame of 12 and 14 months respectively) PA MD0351XXE (talk) 01:43, 21 April 2011 (UTC)[reply]

Update: The patient who was 14 months post Ayurvedic treatment required surgical intervention of the stricture (now 16 months after the Ayurveda was performed)PA MD0351XXE (talk) 22:18, 21 May 2011 (UTC)[reply]

Update #2: The second patient having undergone "Uttarbasti" recently elected to undergo urethroplastic correction of his stricture. The Ayurvedic procedure had been repeated at 17 months with "inadequate response/symptom resolution". Uttarbasti may be a useful adjunct in the ongoing care of the stricture patient, however, it's curative powers appear questionable at best. PA MD0351XXE (talk) 09:57, 27 October 2011 (UTC)[reply]

Article in progress

FYI: I am (slowly) on the process of editing the urethral surgery pages to comply with current medical standards/practices and journal info. I will attempt to have continuity within those pages, so please, bear with me. If any questions, please email. PA MD0351XXE (talk) 00:56, 15 December 2011 (UTC)[reply]

Have just now read your comment here, having followed the link to a discussion of a proposed merger of Meatal stenosis and Urethral stricture. I apologise for not reading the Talk page first; but I have made several small—and fairly obvious—edits to Urethral stricture today to improve clarity for the lay reader. I hope these minor changes will not greatly disrupt your work, but if you find it necessary to revert, please do so. However, I'd ask you to retain the clarifications of such arcana as "filiform" and "bougie", as well—naturally!—as the correct spelling of "dilatation". yoyo (talk) 17:07, 23 February 2012 (UTC)[reply]

Yoyo: My only change to your work was to revert to the original spelling of the term "dilitation". When referencing procedures involving the male and female urethra and the ureters of both sexes, "dilitation" is the accepted spelling in most medical texts and journals; although the grammatically correct version is "dilatation" (that term is used in medical texts and journals to reference instrumental procedures for other parts of the human body). I have, however, seen the traditional spelling used in some European urological texts. I removed the reference to "bougies" for purposes of clarification, and will endeavor to add more info on dilitation with filiform and followers (filiform dilitation) at another time, which should be soon, I hope.PA MD0351XXE (talk) 13:28, 17 June 2012 (UTC)[reply]

Bioengineered urethral research

Dr. Anthony Atala, director of the Wake Forest Institute of Regenerative Medicine has pioneered the first laboratory grown human urethra(s) which were successfully transplanted into humans. I am attempting to contact him for an update of the progress of efficacy trials, and will post the reply on this page when received. This, in my opinion, offers the best hope for revision and repair for the severely compromised male human urethra, and I expect similar findings in with female recipients . PA MD0351XXE (talk) 05:23, 28 June 2012 (UTC)[reply]