Talk:MDMA/Archive 1: Difference between revisions
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There's more to be said about the effects of the drug; it's been called an "empathogen" because of the way it breaks down barriers between people (this is why Shulgin and others were using it in psychotherapy). Also, towards the end of the article it talks about serotonin receptors, but nowhere is it mentioned that MDMA is an SSRI. XTC was another street name. (These are mostly notes to myself; when I get time, and if nobody beats me to it, I'll make these changes...) |
There's more to be said about the effects of the drug; it's been called an "empathogen" because of the way it breaks down barriers between people (this is why Shulgin and others were using it in psychotherapy). Also, towards the end of the article it talks about serotonin receptors, but nowhere is it mentioned that MDMA is an SSRI. XTC was another street name. (These are mostly notes to myself; when I get time, and if nobody beats me to it, I'll make these changes...) |
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:Does that mean if I get a prescription for SSRIs from my doctor, I can take enough of them and get ecstacsy-like effects? :) Also, does ecstacsy have any risk of causing [[:serotonin syndrome|serotonin syndrome]]? -- [[:SJK|SJK]] |
:Does that mean if I get a prescription for SSRIs from my doctor, I can take enough of them and get ecstacsy-like effects? :) Also, does ecstacsy have any risk of causing [[:serotonin syndrome|serotonin syndrome]]? -- [[:SJK|SJK]] |
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Well the dosage most people take in street E is way in excess of the usual pharmacological dosage of things like anti-depression drugs. I assume weird stuff would happen if you OD'd on prescription drugs but its not a course I'd recommend. Very few of the E related deaths have been due to overdose, those that weren't ascribed to external factors (too much/little water etc) where usually put down as allergic reactions. The little experimental evidence so far suggests that long term excessive generation of seratonin causes burn out with low seratonin levels when not under the effect of the drug. |
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Revision as of 02:44, 15 April 2002
Moved to talk:
"Despite popular belief, the drug is not very deadly: the LD50 is 100mg/kg or roughly 70 standard quality clandestine pills. (LD50 is the amount of a substance at which half of those will take this amount will die.)
The dangers today is largely believed to be of a more mental aspect. Severe depression is regarded as the most evident."
- Note that this could be taken to mean that 25% of those who take 35 pills or approximately 2% of those who take three pills will die. However, there is no requirement that the LD50 scale linearly - it could be 0.005% at three pills or 40% - there's no way to tell from the LD50 alone. Also note that the LD50 tells nothing about other side effects - a hypothetical drug might have an LD50 of 75 pills, but 80% of people who take even one pill are rendered permanently parapalegic.
What about other types of "extacsy," such as religious or sexual? F. Lee Horn
- If they're worthy of an encyclopedia article, we have articles called "religious ecstasy" or "sexual ecstasy", and move the contents of this to "ecstasy drug" or similar. We then make up a "pointer page" on the parent to this page pointing to the two or three articles. However, we should probably keep in mind that Wikipedia is not a dictionary. --Robert Merkel
- I realize this, although I seem to see quite a few articles which are not much more than dictionary style definitions. Thank you for the pointers on creating the articles, though. : ) F. Lee Horn
There's more to be said about the effects of the drug; it's been called an "empathogen" because of the way it breaks down barriers between people (this is why Shulgin and others were using it in psychotherapy). Also, towards the end of the article it talks about serotonin receptors, but nowhere is it mentioned that MDMA is an SSRI. XTC was another street name. (These are mostly notes to myself; when I get time, and if nobody beats me to it, I'll make these changes...)
- Does that mean if I get a prescription for SSRIs from my doctor, I can take enough of them and get ecstacsy-like effects? :) Also, does ecstacsy have any risk of causing serotonin syndrome? -- SJK
Well the dosage most people take in street E is way in excess of the usual pharmacological dosage of things like anti-depression drugs. I assume weird stuff would happen if you OD'd on prescription drugs but its not a course I'd recommend. Very few of the E related deaths have been due to overdose, those that weren't ascribed to external factors (too much/little water etc) where usually put down as allergic reactions. The little experimental evidence so far suggests that long term excessive generation of seratonin causes burn out with low seratonin levels when not under the effect of the drug.