Norleucine: Difference between revisions
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| IUPACName = (2S)-2-aminohexanoic acid |
| IUPACName = (2S)-2-aminohexanoic acid |
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| Abbreviation = Nle |
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|OtherNames = |
|OtherNames = |
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Caprine<br /> |
Caprine<br /> |
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| pKa=2.39 (carboxyl), 9.76 (amino)<ref>Dawson, R.M.C., et al., ''Data for Biochemical Research'', Oxford, Clarendon Press, 1959.</ref> |
| pKa=2.39 (carboxyl), 9.76 (amino)<ref>Dawson, R.M.C., et al., ''Data for Biochemical Research'', Oxford, Clarendon Press, 1959.</ref> |
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| Solubility = 16 g/l at 23 °C <ref>[http://search.be.acros.com/msds?for=acros&sup=acros&lang=DE&search=22604&button=Show Sicherheitsdatenblatt Acros.]</ref> |
| Solubility = 16 g/l at 23 °C <ref>[http://search.be.acros.com/msds?for=acros&sup=acros&lang=DE&search=22604&button=Show Sicherheitsdatenblatt Acros.]</ref> |
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| XLogP3 = -1.5 <ref> [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=21236#x27]</ref> |
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| Section7 = {{Chembox Hazards |
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Revision as of 21:00, 13 April 2014
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| Names | |
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| IUPAC name
(2S)-2-aminohexanoic acid
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| Other names
Caprine
Glycoleucine 2-Aminocaproic acid | |
| Identifiers | |
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3D model (JSmol)
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| 1721748 | |
| ChEBI | |
| ChemSpider | |
| DrugBank | |
| ECHA InfoCard | 100.009.512 |
| EC Number |
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| 464584 | |
| KEGG | |
| MeSH | Norleucine |
PubChem CID
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| RTECS number |
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C6H13NO2 | |
| Molar mass | 131.175 g·mol−1 |
| Melting point | 301 °C (decomposes) [1] |
| 16 g/l at 23 °C [2] | |
| Acidity (pKa) | 2.39 (carboxyl), 9.76 (amino)[3] |
| Related compounds | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Norleucine (abbreviated as Nle) is an isomer of leucine, the α-amino acid 2-amino-hexanoic acid. It is not found in natural proteins. Norleucine is used in experimental studies of protein structure and function. It is structurally similar to methionine, however it does not contain sulfur.
See also
- Leucines, description of the isomers of leucine
References
- ^ Hermann Römpp, Jürgen Falbe und Manfred Regitz: Römpp Lexikon Chemie, 9. Auflage, Georg Thieme Verlag, Stuttgart 1992.
- ^ Sicherheitsdatenblatt Acros.
- ^ Dawson, R.M.C., et al., Data for Biochemical Research, Oxford, Clarendon Press, 1959.
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