Talk:LSD

Suicide/agressive behavior not true

Psychedelics not linked to mental health problems or suicidal behavior: a population study. http://www.ncbi.nlm.nih.gov/pubmed/25744618 The sentence stating it is linked with suicide and aggressive behavior should be deleted, it is disinformative.

Medical uses: LSD-assisted psychotherapy for anxiety associated with a life-threatening disease: a qualitative study of acute and sustained subjective effects. http://www.ncbi.nlm.nih.gov/pubmed/25389218 — Preceding unsigned comment added by Dadutch (talk • contribs) 19:58, 9 August 2015 (UTC)

Just some suggestions on the HPPD section

Been doing a lot of research on HPPD and found some stuff that might be helpful to add here. Firstly, it is generally considered HPPD is linked to or a part of visual snow syndrome. Not sure if Vimeo is a good source, but here is an interview with Dr. Henry David Abraham, a leading expert on HPPD, saying that it is most likely a form of visual snow or at least linked to it. This article from Dr. Mark Borgini from Psychology Today also refers to HPPD as a form of visual snow and brings up another topic that should be mentioned. A 2012 study by Dr. Christoph Schankin at the University of Carolina has concluded that it is unlikely that hallucinogen use causes visual snow (therefore, it is unlikely, according to this study, that HPPD exists in the way it is written in the DSM-IV). The article does not cite a source, but I believe this is what it is referring to. Also, the current last sentence of the HPPD section states that J.H. Halpern's 2003 review of the HPPD literature concludes that HPPD is uncommon and affects an already at-risk group. This isn't written anywhere in the review and is assuming a lot. What the review does conclude is that previous studies into HPPD were carried out poorly and filled with confounding variables, particularly when it comes to poly-drug use, as well as being unclear about the definition of flashbacks and their relation to HPPD. — Preceding unsigned comment added by 220.244.162.100 (talk) 15:54, 13 August 2015 (UTC)

Interesting. We'd have to find some better WP:MEDRS sources but this could be worth adding. I'm currently occupied with other articles but perhaps someone else can add it. Sizeofint (talk) 19:54, 13 August 2015 (UTC)

Synthesis

Synthesis needs expanded, preferably with equations and reaction mechanisms, and explanations with reagents and solvents with purification, unless that is illegal or whatever. Jamez Z23 (talk) 15:52, 16 August 2015 (UTC)

There is no legal problem, but Wikipedia policy is not to give procedural information. It views itself as an encyclopedia, not a how-to book. See WP:NOTMANUAL.--Smokefoot (talk) 16:00, 16 August 2015 (UTC)

The content can be added in an encyclopedic manner. See Amphetamine#Synthesis for example. What we cannot do (per policy, not legality) is write step by step instructions for LSD synthesis. Sizeofint (talk) 20:30, 16 August 2015 (UTC)

You only have to mention it is purified, and what solvents are added, not how to do it. Like it is purified by distillation, but not how to do the distillation or what temperature or whatever. Only a basic overview. The main addition would be the synthetic reaction equations (reaction equations / mechanisms are informative, not instructional)

It is synthesised from lysergic acid, for example using trifluoroacetic acid to make lysergic trifluoroacetic acid, followed by addition of diethylamine to form lysergic acid diethylamide. You could use reaction equations instead of just instructing how to do it, and leave it at that if you prefer.

They did that with amphetamine and methamphetamine, so I don't see why not.

Jamez Z23 (talk) 22:57, 17 August 2015 (UTC)

External links modified

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Anxiety/Panic

I added this under Dangers. Anxiety and panic attacks are the most common LSD-related adverse effects. I'll add some references, or maybe somebody else could expand on this.

Also under dangers, there are death attributed to people's reaction to the drug, ie they do something while high that causes death. ie jump out window, cut wrist etc...

Panic attacks can occur if the environment becomes spooky or unsafe for the individual, Make sure you surround yourself with good people and in a safe environment away from dangerous equipment. — Preceding unsigned comment added by 2601:601:500:7402:B8B0:162:9949:EAE5 (talk) 06:23, 27 September 2015 (UTC)

The article history doesn't show any edit of the sort you describe. Since the article is semi-protected (due to high levels of vandalism and counterproductive edits), you wouldn't be able to edit it directly without registering an account. If you would like to suggest an edit, you can do so here, but note that all edits need to be supported by reputable published sources. Best regards, Looie496 (talk) 11:58, 27 September 2015 (UTC)

History

This is grand little article and always a pleasure to see all the hard work that is put into creating these pages. It seems however that the history of the modern chemists that put forth so much effort into developing this medication, studying it, bringing forth new intermediates, and pioneering more cost effective and faster reactions have faded from the memory of the world. Some of these chemist even gave up their freedom in order to promote understanding of the nature of this substance in a time when research groups would not touch the topic. I see the mention of Tim Skully but it was actually Nicholas Sand that was the true chemist that engineered the reactions used, and it was ALD-52 Skully was promoting not LSD proof via court records. Where is the chemist William Henderson known as Dr Flowerchild throughtout the world for developing hundreds of intermediates and argon reactions that know find themselves being used in the academic and pharmaceutical structures of society, the same society that seeks to hide his existence and donation to science. Casey Hardison and William Pickard are two more chemist that risked everything to bring this substance to the world and for us to gain insight into its structure. Without these hidden away chemists there would not be a movement to push for therapeutics during the time span from the 80s to the new millennium when the benefits of this substance was most suppressed. Simpletruths (talk) 15:20, 16 January 2016 (UTC)

There is History of lysergic acid diethylamide Sizeofint (talk) 17:06, 16 January 2016 (UTC)

Agreed, there is somewhat of a history mentioned but it would seem that some expounding upon the topic should be desired for the sake of academic research assistance and to simply reward other chemist in words for their contributions to science that has brought about a new generation that now have the tools to produce better therapeutic applications for this medication resultant only because of the unmentioned historical chemist denied by the article. Simpletruths (talk) 02:08, 17 January 2016 (UTC)

My apologies upon this topic. I did go to the link provided by Sizeofint and discovered some history on the subject. In light of this I shall bow out on making any suggestions on change that may encompass this article ans proceed to weigh in on the article found to explain the history there of. Thank you very much for your time and guidance. Simpletruths (talk) 02:16, 17 January 2016 (UTC)