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== Biography ==
== Biography ==
She grew up in [[Concord, Massachusetts]] and she received her degree in Biology from [[Harvard University]] in 1991. After graduating from Harvard, she completed her Ph.D program in Neuroscience at [[Stanford University]] in 1998. Following the completion of this Ph.D program, she did a postdoctoral fellowship under Marc Tessier-Lavigne at the [[University of California]]. While concluding her postdoctoral fellowship, she cultivated a particular interest in the auditory system and utilized her familiarity with molecular genetics and cell behavior, and applied it to the sensory system. Lisa currently resides in [[Newton, Massachusetts]]. She enjoys reading and cooking.<ref>{{cite web|last1=Goodrich|first1=Lisa|title=Lisa Goodrich, PhD|url=http://dms.hms.harvard.edu/neuroscience/fac/goodrich.php|publisher=[[Harvard University]]|accessdate=20 December 2015}}</ref>
She grew up in [[Concord, Massachusetts]] and she received her degree in Biology from [[Harvard University]] in 1991. After graduating from Harvard, she completed her Ph.D program in Neuroscience at [[Stanford University]] in 1998. Following the completion of this Ph.D program, she did a postdoctoral fellowship under Marc Tessier-Lavigne at the [[University of California]]. While concluding her postdoctoral fellowship, she cultivated a particular interest in the auditory system and utilized her familiarity with molecular genetics and cell behavior, and applied it to the sensory system. Lisa currently resides in [[Newton, Massachusetts]]. She enjoys reading and cooking.<ref>{{cite web|last1=Goodrich |first1=Lisa |title=Lisa Goodrich, PhD |url=http://dms.hms.harvard.edu/neuroscience/fac/goodrich.php |publisher=[[Harvard University]] |accessdate=20 December 2015 |deadurl=yes |archiveurl=https://web.archive.org/web/20151017065955/http://dms.hms.harvard.edu/neuroscience/fac/Goodrich.php |archivedate=17 October 2015 |df= }}</ref>


== Research ==
== Research ==
In her laboratory, her group studies the cellular and molecular mechanisms that impact the development of [[Biological neural network|neural circuits]]. The stages of development being studied are determination, differentiation, how [[Axon|axonal connections]] are formed, and generation of behavior. Her research program focuses on detecting genes necessary for hearing and balance. Her research hopes to connect molecular pathways that are essential in [[cochlea]] development, and to influence these pathways to repair the cochlea after suffering damage.<ref>{{cite web|title=Lab Members|url=http://goodrich.med.harvard.edu/lab-members.html|publisher=Goodrich Lab|accessdate=20 December 2015}}</ref> It focuses on how the steps of circuit assembly coincide to construct neural networks that are committed to particular functions. In order to do so, research from mouse [[molecular genetics]] and [[genomics]] is studied to discover how circuit assembly is regulated. The two main assemblies she studies are the auditory circuit assembly and the rental circuit assembly.<ref>{{cite web|title=Research|url=http://goodrich.med.harvard.edu/research.html|publisher=Goodrich Lab|accessdate=20 December 2015}}</ref> Her lab utilizes various genetic techniques in mice and [[Assay|biochemical assays]] and [[Embryology|embryological]] studies in chicks. She also uses [[forward genetics|forward]] and [[reverse genetics|reverse]] genetic approaches in mice to gain an understanding of how genetic [[mutation]]s can lead to fluctuations in hearing and balances..<ref>{{cite web|title=Restoring Hearing|url=http://www.actiononhearingloss.org.uk/your-hearing/biomedical-research/projects-and-research/researchers-and-phd-students/researchers/restoring-hearing/lisa-goodrich.aspx|publisher=[[Action on Hearing Loss]]|accessdate=20 December 2015}}</ref>
In her laboratory, her group studies the cellular and molecular mechanisms that impact the development of [[Biological neural network|neural circuits]]. The stages of development being studied are determination, differentiation, how [[Axon|axonal connections]] are formed, and generation of behavior. Her research program focuses on detecting genes necessary for hearing and balance. Her research hopes to connect molecular pathways that are essential in [[cochlea]] development, and to influence these pathways to repair the cochlea after suffering damage.<ref>{{cite web|title=Lab Members |url=http://goodrich.med.harvard.edu/lab-members.html |publisher=Goodrich Lab |accessdate=20 December 2015 |deadurl=yes |archiveurl=https://web.archive.org/web/20160105044200/http://goodrich.med.harvard.edu/lab-members.html |archivedate= 5 January 2016 |df= }}</ref> It focuses on how the steps of circuit assembly coincide to construct neural networks that are committed to particular functions. In order to do so, research from mouse [[molecular genetics]] and [[genomics]] is studied to discover how circuit assembly is regulated. The two main assemblies she studies are the auditory circuit assembly and the rental circuit assembly.<ref>{{cite web|title=Research|url=http://goodrich.med.harvard.edu/research.html|publisher=Goodrich Lab|accessdate=20 December 2015}}</ref> Her lab utilizes various genetic techniques in mice and [[Assay|biochemical assays]] and [[Embryology|embryological]] studies in chicks. She also uses [[forward genetics|forward]] and [[reverse genetics|reverse]] genetic approaches in mice to gain an understanding of how genetic [[mutation]]s can lead to fluctuations in hearing and balances..<ref>{{cite web|title=Restoring Hearing|url=http://www.actiononhearingloss.org.uk/your-hearing/biomedical-research/projects-and-research/researchers-and-phd-students/researchers/restoring-hearing/lisa-goodrich.aspx|publisher=[[Action on Hearing Loss]]|accessdate=20 December 2015}}</ref>


She also studies [[morphogenesis]], and how this developmental event is essential in how the nervous system functions.<ref name="resources">{{cite web|title=Resources|url=http://goodrich.med.harvard.edu/resources.html|publisher=Goodrich Lab|accessdate=20 December 2015}}</ref> Goodrich currently has 42 publications on research relative to the [[sensory system]] and [[neurobiology]]. Among them are her articles on "Morphological and physiological development of auditory synapses," "Gata3 is a critical regulator of cochlear wiring," and "Deaf and dizzy mice: A genetic dissection of inner ear development."<ref name="people">{{cite web|title=Department of Neurobiology|url=http://neuro.hms.harvard.edu/people/faculty|publisher=[[Harvard Medical School]]|accessdate=20 December 2015}}</ref> She also studies [[morphogenesis]], and how this developmental event is essential in how the nervous system functions.<ref name="resources">{{cite web|title=Resources|url=http://goodrich.med.harvard.edu/resources.html|publisher=Goodrich Lab|accessdate=20 December 2015}}</ref>
She also studies [[morphogenesis]], and how this developmental event is essential in how the nervous system functions.<ref name="resources">{{cite web|title=Resources|url=http://goodrich.med.harvard.edu/resources.html|publisher=Goodrich Lab|accessdate=20 December 2015}}</ref> Goodrich currently has 42 publications on research relative to the [[sensory system]] and [[neurobiology]]. Among them are her articles on "Morphological and physiological development of auditory synapses," "Gata3 is a critical regulator of cochlear wiring," and "Deaf and dizzy mice: A genetic dissection of inner ear development."<ref name="people">{{cite web|title=Department of Neurobiology|url=http://neuro.hms.harvard.edu/people/faculty|publisher=[[Harvard Medical School]]|accessdate=20 December 2015}}</ref> She also studies [[morphogenesis]], and how this developmental event is essential in how the nervous system functions.<ref name="resources">{{cite web|title=Resources|url=http://goodrich.med.harvard.edu/resources.html|publisher=Goodrich Lab|accessdate=20 December 2015}}</ref>

Revision as of 18:39, 16 May 2017

Lisa V. Goodrich is a Professor in the Department of Neurobiology at the Harvard Medical School.

Lisa Goodrich
Born
NationalityAmerican
Alma materHarvard University
Stanford University
Scientific career
FieldsNeurobiology
InstitutionsHarvard University
Doctoral advisorMatthew Scott
Websitegoodrich.med.harvard.edu

Biography

She grew up in Concord, Massachusetts and she received her degree in Biology from Harvard University in 1991. After graduating from Harvard, she completed her Ph.D program in Neuroscience at Stanford University in 1998. Following the completion of this Ph.D program, she did a postdoctoral fellowship under Marc Tessier-Lavigne at the University of California. While concluding her postdoctoral fellowship, she cultivated a particular interest in the auditory system and utilized her familiarity with molecular genetics and cell behavior, and applied it to the sensory system. Lisa currently resides in Newton, Massachusetts. She enjoys reading and cooking.[1]

Research

In her laboratory, her group studies the cellular and molecular mechanisms that impact the development of neural circuits. The stages of development being studied are determination, differentiation, how axonal connections are formed, and generation of behavior. Her research program focuses on detecting genes necessary for hearing and balance. Her research hopes to connect molecular pathways that are essential in cochlea development, and to influence these pathways to repair the cochlea after suffering damage.[2] It focuses on how the steps of circuit assembly coincide to construct neural networks that are committed to particular functions. In order to do so, research from mouse molecular genetics and genomics is studied to discover how circuit assembly is regulated. The two main assemblies she studies are the auditory circuit assembly and the rental circuit assembly.[3] Her lab utilizes various genetic techniques in mice and biochemical assays and embryological studies in chicks. She also uses forward and reverse genetic approaches in mice to gain an understanding of how genetic mutations can lead to fluctuations in hearing and balances..[4]

She also studies morphogenesis, and how this developmental event is essential in how the nervous system functions.[5] Goodrich currently has 42 publications on research relative to the sensory system and neurobiology. Among them are her articles on "Morphological and physiological development of auditory synapses," "Gata3 is a critical regulator of cochlear wiring," and "Deaf and dizzy mice: A genetic dissection of inner ear development."[6] She also studies morphogenesis, and how this developmental event is essential in how the nervous system functions.[5]

Publications

She currently has 42 publications. Among them are her articles on "Morphological and physiological development of auditory synapses," "Gata3 is a critical regulator of cochlear wiring," and "Deaf and dizzy mice: A genetic dissection of inner ear development."[6]

Her laboratory has also created a number of resources that are made available to other researchers who have an interest in the inner ear and its development.[7]

Honors

In 1999 she was the recipient of a regional award from AAAS Science journal for her essay on “Patching together development and disease." This essay was based on her work in the department of Developmental Biology at Stanford University.[8]

References

  1. ^ Goodrich, Lisa. "Lisa Goodrich, PhD". Harvard University. Archived from the original on 17 October 2015. Retrieved 20 December 2015. {{cite web}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)
  2. ^ "Lab Members". Goodrich Lab. Archived from the original on 5 January 2016. Retrieved 20 December 2015. {{cite web}}: Unknown parameter |deadurl= ignored (|url-status= suggested) (help)
  3. ^ "Research". Goodrich Lab. Retrieved 20 December 2015.
  4. ^ "Restoring Hearing". Action on Hearing Loss. Retrieved 20 December 2015.
  5. ^ a b "Resources". Goodrich Lab. Retrieved 20 December 2015.
  6. ^ a b "Department of Neurobiology". Harvard Medical School. Retrieved 20 December 2015.
  7. ^ "Lisa Goodrich". Harvard Medical School. Retrieved 20 December 2015.
  8. ^ "Winning Entries". sciencemag.org. American Association for the Advancement of Science. Retrieved 20 December 2015.