Ent-isokaurene C2-hydroxylase: Difference between revisions
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'''Ent-isokaurene C2-hydroxylase''' ({{EC number|1.14.13.143}}, ''CYP71Z6'') is an [[enzyme]] with [[List of enzymes|systematic name]] ''ent-isokaurene,NADPH:oxygen oxidoreductase (hydroxylating)''.<ref>{{cite journal | title = Parsing a multifunctional biosynthetic gene cluster from rice: |
'''Ent-isokaurene C2-hydroxylase''' ({{EC number|1.14.13.143}}, ''CYP71Z6'') is an [[enzyme]] with [[List of enzymes|systematic name]] ''ent-isokaurene,NADPH:oxygen oxidoreductase (hydroxylating)''.<ref>{{cite journal | vauthors = Wu Y, Hillwig ML, Wang Q, Peters RJ | title = Parsing a multifunctional biosynthetic gene cluster from rice: Biochemical characterization of CYP71Z6 & 7 | journal = FEBS Letters | volume = 585 | issue = 21 | pages = 3446–51 | date = November 2011 | pmid = 21985968 | pmc = 3227696 | doi = 10.1016/j.febslet.2011.09.038 }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]] |
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: ent-isokaurene + O<sub>2</sub> + NADPH + H<sup>+</sup> <math>\rightleftharpoons</math> ent-2alpha-hydroxyisokaurene + H<sub>2</sub>O + NADP<sup>+</sup> |
: ent-isokaurene + O<sub>2</sub> + NADPH + H<sup>+</sup> <math>\rightleftharpoons</math> ent-2alpha-hydroxyisokaurene + H<sub>2</sub>O + NADP<sup>+</sup> |
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[[Category:EC 1.14.13]] |
[[Category:EC 1.14.13]] |
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{{Enzyme-stub}} |
{{Enzyme-stub}} |
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Revision as of 16:44, 22 March 2019
| Ent-isokaurene C2-hydroxylase | |||||||||
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| Identifiers | |||||||||
| EC no. | 1.14.13.143 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Ent-isokaurene C2-hydroxylase (EC 1.14.13.143, CYP71Z6) is an enzyme with systematic name ent-isokaurene,NADPH:oxygen oxidoreductase (hydroxylating).[1] This enzyme catalyses the following chemical reaction
- ent-isokaurene + O2 + NADPH + H+ ent-2alpha-hydroxyisokaurene + H2O + NADP+
Ent-isokaurene C2-hydroxylase performs the initial step in the conversion of ent-isokaurene to the antibacterial oryzalides in rice, Oryza sativa.
References
- ^ Wu Y, Hillwig ML, Wang Q, Peters RJ (November 2011). "Parsing a multifunctional biosynthetic gene cluster from rice: Biochemical characterization of CYP71Z6 & 7". FEBS Letters. 585 (21): 3446–51. doi:10.1016/j.febslet.2011.09.038. PMC 3227696. PMID 21985968.
External links
- Ent-isokaurene+C2-hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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