PCDHA4: Difference between revisions

PCDHA4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WUZ
Identifiers
Aliases	PCDHA4, CNR1, CNRN1, CRNR1, PCDH-ALPHA4, protocadherin alpha 4
External IDs	OMIM: 606310; MGI: 1298406; HomoloGene: 130626; GeneCards: PCDHA4; OMA:PCDHA4 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	141,012,347 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	37,320,714 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; islet of Langerhans; ; prefrontal cortex; ; ganglionic eminence; ; gallbladder; ; superior frontal gyrus; ; ventricular zone; ; Cerebellum; ; cerebellar cortex; ; cerebellar hemisphere;
	Top expressed in
	hippocampus proper; ; dentate gyrus of hippocampal formation granule cell; ; embryo; ; granular layer; ; Cortex of frontal lobe; ; primary visual cortex; ; superior frontal gyrus; ; granular layer of dentate gyrus; ; Purkinje cell; ; Region I of hippocampus proper;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; calcium ion binding; metal ion binding; identical protein binding;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane; endoplasmic reticulum; synapse;
Biological process	cell adhesion; nervous system development; homophilic cell adhesion via plasma membrane adhesion molecules; cell-cell signaling;
	Sources:Amigo / QuickGO
Orthologs
	56144
	12936
	ENSG00000204967
	ENSMUSG00000104252
	Q9UN74
	O88689
	NM_031500; NM_018907
	NM_007766
	NP_061730; NP_113688
	NP_001167625
	Wikidata
View/Edit Human	View/Edit Mouse

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Revision as of 01:31, 2 June 2018

Protocadherin alpha-4 is a protein that in humans is encoded by the PCDHA4 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000204967 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000104252 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wu Q, Maniatis T (Jul 1999). "A striking organization of a large family of human neural cadherin-like cell adhesion genes". Cell. 97 (6): 779–90. doi:10.1016/S0092-8674(00)80789-8. PMID 10380929.
^ Sugino H, Hamada S, Yasuda R, Tuji A, Matsuda Y, Fujita M, Yagi T (Apr 2000). "Genomic organization of the family of CNR cadherin genes in mice and humans". Genomics. 63 (1): 75–87. doi:10.1006/geno.1999.6066. PMID 10662547.
^ "Entrez Gene: PCDHA4 protocadherin alpha 4".

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-{{Underlinked|date=June 2016}}
 {{Infobox_gene}}
 '''Protocadherin alpha-4''' is a [[protein]] that in humans is encoded by the ''PCDHA4'' [[gene]].<ref name="pmid10380929">{{cite journal | vauthors = Wu Q, Maniatis T | title = A striking organization of a large family of human neural cadherin-like cell adhesion genes | journal = Cell | volume = 97 | issue = 6 | pages = 779–90 |date=Jul 1999 | pmid = 10380929 | pmc =  | doi =10.1016/S0092-8674(00)80789-8  }}</ref><ref name="pmid10662547">{{cite journal | vauthors = Sugino H, Hamada S, Yasuda R, Tuji A, Matsuda Y, Fujita M, Yagi T | title = Genomic organization of the family of CNR cadherin genes in mice and humans | journal = Genomics | volume = 63 | issue = 1 | pages = 75–87 |date=Apr 2000 | pmid = 10662547 | pmc =  | doi = 10.1006/geno.1999.6066 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PCDHA4 protocadherin alpha 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56144| accessdate = }}</ref>

Revision as of 01:31, 2 June 2018

References

Further reading