Janeway lesion: Difference between revisions
m Task 18 (cosmetic): eval 4 templates: del empty params (6×); del |url-status= (1×); |
Ozzie10aaaa (talk | contribs) m Cleaned up using AutoEd |
||
| Line 1: | Line 1: | ||
{{Infobox medical condition (new) |
{{Infobox medical condition (new) |
||
| name = Janeway lesion |
| name = Janeway lesion |
||
| synonyms = |
| synonyms = |
||
| image = Janeway lesion.JPG |
| image = Janeway lesion.JPG |
||
| caption = |
| caption = |
||
| pronounce = |
| pronounce = |
||
| field = *[[Cardiology]] |
| field = *[[Cardiology]] |
||
*[[Dermatology]] |
* [[Dermatology]] |
||
| symptoms = Painless red flat papules on palms and soles. |
| symptoms = Painless red flat papules on palms and soles. |
||
| complications = |
| complications = |
||
| onset = Sudden |
| onset = Sudden |
||
| duration = Days to weeks |
| duration = Days to weeks |
||
| types = |
| types = |
||
| causes = [[Infective endocarditis]] |
| causes = [[Infective endocarditis]] |
||
| risks = |
| risks = |
||
| diagnosis = |
| diagnosis = |
||
| differential = [[Osler's nodes]] |
| differential = [[Osler's nodes]] |
||
| prevention = |
| prevention = |
||
| treatment = |
| treatment = |
||
| medication = |
| medication = |
||
| prognosis = |
| prognosis = |
||
| frequency = |
| frequency = |
||
| deaths = |
| deaths = |
||
}} |
}} |
||
'''Janeway lesions''' are rare, non-[[Tenderness (medicine)|tender]], small [[erythematous]] or [[haemorrhagic]] [[macule|macular]], [[papule|papular]] or [[Nodule (medicine)|nodular]] lesions on the palms or [[Sole (foot)|soles]] only a few millimeters in diameter that are associated with [[infective endocarditis]] and often indistinguishable from [[Osler's nodes]].<ref name=DermnetNZ>{{Cite web|url=https://www.dermnetnz.org/topics/osler-nodes-and-janeway-lesions/|title=Osler nodes and Janeway lesions {{!}} DermNet NZ|website=www.dermnetnz.org|access-date=2 October 2019}}</ref><ref name = "Farrior">{{cite journal | last = Farrior | first = J.B. |author2=Silverman M.E. | title = A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis |journal = Chest | volume = 70 | issue = 2 | pages = 239–243 | year = 1976 | pmid = 947688 | doi = 10.1378/chest.70.2.239}}</ref> |
'''Janeway lesions''' are rare, non-[[Tenderness (medicine)|tender]], small [[erythematous]] or [[haemorrhagic]] [[macule|macular]], [[papule|papular]] or [[Nodule (medicine)|nodular]] lesions on the palms or [[Sole (foot)|soles]] only a few millimeters in diameter that are associated with [[infective endocarditis]] and often indistinguishable from [[Osler's nodes]].<ref name=DermnetNZ>{{Cite web|url=https://www.dermnetnz.org/topics/osler-nodes-and-janeway-lesions/|title=Osler nodes and Janeway lesions {{!}} DermNet NZ|website=www.dermnetnz.org|access-date=2 October 2019}}</ref><ref name = "Farrior">{{cite journal | last = Farrior | first = J.B. |author2=Silverman M.E. | title = A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis |journal = Chest | volume = 70 | issue = 2 | pages = 239–243 | year = 1976 | pmid = 947688 | doi = 10.1378/chest.70.2.239}}</ref> |
||
| Line 44: | Line 44: | ||
==History== |
==History== |
||
Janeway lesions are named after [[Edward Gamaliel Janeway|Edward Janeway]] (1841–1911), a prominent American physician, pathologist and contemporary of Sir [[William Osler]], who initially described "peculiar skin lesions" in some people with endocarditis, in a paper published in 1899. The term was first used by [[internal medicine|internist]] and pathologist [[Emanuel Libman]], who reported the lesions in his paper of 1906 and explained his reasoning for using the term "Janeway lesions" in a footnote in 1923. Osler never mentioned Janeway lesions. The inclusion into Osler's 1925 textbook came six years after Osler died.<ref name=prutkin>{{cite journal|title=Edward G. Janeway, Clinician and Pathologist|authors=Jordan Prutkin, [[W. Bruce Fye]]|journal=[[Clinical Cardiology]]|volume=29|issue = 8|pages= |
Janeway lesions are named after [[Edward Gamaliel Janeway|Edward Janeway]] (1841–1911), a prominent American physician, pathologist and contemporary of Sir [[William Osler]], who initially described "peculiar skin lesions" in some people with endocarditis, in a paper published in 1899. The term was first used by [[internal medicine|internist]] and pathologist [[Emanuel Libman]], who reported the lesions in his paper of 1906 and explained his reasoning for using the term "Janeway lesions" in a footnote in 1923. Osler never mentioned Janeway lesions. The inclusion into Osler's 1925 textbook came six years after Osler died.<ref name=prutkin>{{cite journal|title=Edward G. Janeway, Clinician and Pathologist|authors=Jordan Prutkin, [[W. Bruce Fye]]|journal=[[Clinical Cardiology]]|volume=29|issue = 8|pages=376–377|year=2006|doi=10.1002/clc.4960290815|pmid=16933584|pmc=6654287}}</ref> |
||
==See also== |
==See also== |
||
| Line 55: | Line 55: | ||
== External links == |
== External links == |
||
{{Medical resources |
{{Medical resources |
||
| DiseasesDB = |
| DiseasesDB = |
||
| ICD10 = A41.8 ([[ILDS]] A41.820) |
| ICD10 = A41.8 ([[ILDS]] A41.820) |
||
| ICD9 = |
| ICD9 = |
||
| ICDO = |
| ICDO = |
||
| OMIM = |
| OMIM = |
||
| MedlinePlus = |
| MedlinePlus = |
||
| eMedicineSubj = |
| eMedicineSubj = |
||
| eMedicineTopic = |
| eMedicineTopic = |
||
| MeshID = |
| MeshID = |
||
}} |
}} |
||
{{Cardiovascular system symptoms and signs}} |
{{Cardiovascular system symptoms and signs}} |
||
Revision as of 19:14, 16 February 2021
| Janeway lesion | |
|---|---|
 | |
| Specialty | |
| Symptoms | Painless red flat papules on palms and soles. |
| Usual onset | Sudden |
| Duration | Days to weeks |
| Causes | Infective endocarditis |
| Differential diagnosis | Osler's nodes |
Janeway lesions are rare, non-tender, small erythematous or haemorrhagic macular, papular or nodular lesions on the palms or soles only a few millimeters in diameter that are associated with infective endocarditis and often indistinguishable from Osler's nodes.[1][2]
Definition
Janeway lesions are painless, frequently haemorrhagic lesions seen most commonly on the palms and soles, particularly on the base of the thumb and little finger, and seen in infective endocarditis.[1]
Differential
Osler's nodes and Janeway lesions are similar and point to the same diagnostic conclusion. The only noted difference between the two is that Osler's nodes present with tenderness, while Janeway lesions do not.[2]
Pathophysiology
Pathologically, the lesion is described to be a microabscess of the dermis with marked necrosis and inflammatory infiltrate not involving the epidermis.[2]
They are caused by septic emboli which deposit bacteria, forming microabscesses.[3] Organisms may be cultured from the lesions.[4]
Diagnosis
Janeway lesions present as red, painless macules and papules on the palms and soles.[1]
They are not common and are frequently indistinguishable from Osler's nodes. Rarely, they have been reported in cases of Systemic lupus erythematosis (SLE), Gonococcemia (disseminated gonorrhoea), haemolytic anaemia and typhoid fever.[1]
They may last days to weeks before completely resolving.[1]
History
Janeway lesions are named after Edward Janeway (1841–1911), a prominent American physician, pathologist and contemporary of Sir William Osler, who initially described "peculiar skin lesions" in some people with endocarditis, in a paper published in 1899. The term was first used by internist and pathologist Emanuel Libman, who reported the lesions in his paper of 1906 and explained his reasoning for using the term "Janeway lesions" in a footnote in 1923. Osler never mentioned Janeway lesions. The inclusion into Osler's 1925 textbook came six years after Osler died.[5]
See also
References
- ^ a b c d e "Osler nodes and Janeway lesions | DermNet NZ". www.dermnetnz.org. Retrieved 2 October 2019.
- ^ a b c Farrior, J.B.; Silverman M.E. (1976). "A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis". Chest. 70 (2): 239–243. doi:10.1378/chest.70.2.239. PMID 947688.
- ^ Mandell, Douglas, Bennett's Principles and Practice of Infectious Diseases, 7th ed., Churchill Livingstone (2009).
- ^ Patterson, James W. (2016). "8. The Vasculopathic Reaction Pattern". Weedon's Skin Pathology (4th ed.). Churchill Livingston. pp. 239–240. ISBN 9780702051838.
- ^ "Edward G. Janeway, Clinician and Pathologist". Clinical Cardiology. 29 (8): 376–377. 2006. doi:10.1002/clc.4960290815. PMC 6654287. PMID 16933584.
{{cite journal}}: Unknown parameter|authors=ignored (help)