Bubble oxygenator: Difference between revisions
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A '''bubble oxygenator''' is an early implementation of the [[oxygenator]] used for [[cardiopulmonary bypass]]. It has since been supplanted by the [[membrane oxygenator]]<ref>{{cite journal|authors=J E Liddicoat, S M Bekassy, A C Beall, Jr, D H Glaeser, and M E DeBakey|title=Membrane vs bubble oxygenator: clinical comparison|journal=Ann Surg|date=May 1975|volume=181|issue=5|pages=747–753|pmc=1345584|pmid=1079448|doi=10.1097/00000658-197505000-00033}}</ref> |
A '''bubble oxygenator''' is an early implementation of the [[oxygenator]] used for [[cardiopulmonary bypass]]. It has since been supplanted by the [[membrane oxygenator]]<ref>{{cite journal|authors=J E Liddicoat, S M Bekassy, A C Beall, Jr, D H Glaeser, and M E DeBakey|title=Membrane vs bubble oxygenator: clinical comparison|journal=Ann Surg|date=May 1975|volume=181|issue=5|pages=747–753|pmc=1345584|pmid=1079448|doi=10.1097/00000658-197505000-00033}}</ref> |
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as a result of advances in material science. Some continue to promote it as a low-cost alternative allowing greater self-sufficiency.<ref name=Leonard>{{cite journal|last=Leonard|first=Ronald J|title=The transition from the bubble oxygenator to the microporous membrane oxygenator|journal=Perfusion|date=2003|volume=18|pages=179–183|url=http://webmedia.unmc.edu/alliedhealth/holt/10378529.pdf|accessdate=3 February 2014|location=Stafford, Virginia|doi=10.1191/0267659103pf659oa}}</ref>{{rp|p.182}} |
as a result of advances in material science. Some continue to promote it as a low-cost alternative allowing greater self-sufficiency.<ref name=Leonard>{{cite journal|last=Leonard|first=Ronald J|title=The transition from the bubble oxygenator to the microporous membrane oxygenator|journal=Perfusion|date=2003|volume=18|issue=3|pages=179–183|url=http://webmedia.unmc.edu/alliedhealth/holt/10378529.pdf|accessdate=3 February 2014|location=Stafford, Virginia|doi=10.1191/0267659103pf659oa|pmid=12952125|s2cid=17750817}}</ref>{{rp|p.182}} |
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== History == |
== History == |
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[[Cardiac surgery|Open-heart surgery]] developed rapidly beginning in the 1950s, and many methods were developed for oxygenating blood outside the body. A bubble oxygenator was introduced in 1950 by Clark, Gollan, and Gupta.<ref>{{cite journal|authors=A.B. Cassie, A.G. Riddell, P.0. Yates|title=Hazard of antifoam emboli from a bubble oxygenator|journal=Thorax|date=1960|volume=15|pages=22–29|url= |
[[Cardiac surgery|Open-heart surgery]] developed rapidly beginning in the 1950s, and many methods were developed for oxygenating blood outside the body. A bubble oxygenator was introduced in 1950 by Clark, Gollan, and Gupta.<ref>{{cite journal|authors=A.B. Cassie, A.G. Riddell, P.0. Yates|title=Hazard of antifoam emboli from a bubble oxygenator|journal=Thorax|date=1960|volume=15|pages=22–29|url= |issue=1|doi=10.1136/thx.15.1.22|pmc=1018529|pmid=13808227}}</ref> The method faced initial skepticism<ref name=Gravlee>{{cite book|author=C. Walton Lillehei|chapter=Historical development of cardiopulmonary bypass in Minnesota|title=Cardiopulmonary Bypass: Principles and Practice|date=2008|publisher=Lippincott Williams & Wilkins|pages=11–18|isbn=9780781768153|url=https://books.google.com/books?id=M5sbCxd5cioC|editor=Glenn P. Gravlee|accessdate=3 February 2014|format=Online}}</ref>{{rp|p.11}} but in 1956 the University of Minnesota's [[Richard DeWall|De-Wall]]-[[C. Walton Lillehei|Lillehei]] bubble oxygenator was demonstrated to be relatively simple, inexpensive, and easy to operate.<ref name=Gravlee/>{{rp|p.16}} |
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The device faced competition from membrane oxygenators, which arrived within the same decade and were found to provide better oxygenation for periods over eight hours, and other advantages beyond six hours.<ref name=Gravlee/>{{rp|p.16}} However, most [[cardiac surgery|open-heart operations]] were substantially shorter,<ref name=Gravlee/>{{rp|p.18}} and by 1976 the bubble oxygenator was predominant.<ref name=Gravlee/>{{rp|p.16}} |
The device faced competition from membrane oxygenators, which arrived within the same decade and were found to provide better oxygenation for periods over eight hours, and other advantages beyond six hours.<ref name=Gravlee/>{{rp|p.16}} However, most [[cardiac surgery|open-heart operations]] were substantially shorter,<ref name=Gravlee/>{{rp|p.18}} and by 1976 the bubble oxygenator was predominant.<ref name=Gravlee/>{{rp|p.16}} |
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Revision as of 21:45, 11 May 2021
A bubble oxygenator is an early implementation of the oxygenator used for cardiopulmonary bypass. It has since been supplanted by the membrane oxygenator[1] as a result of advances in material science. Some continue to promote it as a low-cost alternative allowing greater self-sufficiency.[2]: p.182
History
Open-heart surgery developed rapidly beginning in the 1950s, and many methods were developed for oxygenating blood outside the body. A bubble oxygenator was introduced in 1950 by Clark, Gollan, and Gupta.[3] The method faced initial skepticism[4]: p.11 but in 1956 the University of Minnesota's De-Wall-Lillehei bubble oxygenator was demonstrated to be relatively simple, inexpensive, and easy to operate.[4]: p.16
The device faced competition from membrane oxygenators, which arrived within the same decade and were found to provide better oxygenation for periods over eight hours, and other advantages beyond six hours.[4]: p.16 However, most open-heart operations were substantially shorter,[4]: p.18 and by 1976 the bubble oxygenator was predominant.[4]: p.16
In the 1980s, microporous membrane oxygenators were developed, and replaced bubble oxygenators in most applications.[2][4]: p.18
References
- ^ "Membrane vs bubble oxygenator: clinical comparison". Ann Surg. 181 (5): 747–753. May 1975. doi:10.1097/00000658-197505000-00033. PMC 1345584. PMID 1079448.
{{cite journal}}: Unknown parameter|authors=ignored (help) - ^ a b Leonard, Ronald J (2003). "The transition from the bubble oxygenator to the microporous membrane oxygenator" (PDF). Perfusion. 18 (3). Stafford, Virginia: 179–183. doi:10.1191/0267659103pf659oa. PMID 12952125. S2CID 17750817. Retrieved 3 February 2014.
- ^ "Hazard of antifoam emboli from a bubble oxygenator". Thorax. 15 (1): 22–29. 1960. doi:10.1136/thx.15.1.22. PMC 1018529. PMID 13808227.
{{cite journal}}: Unknown parameter|authors=ignored (help) - ^ a b c d e f C. Walton Lillehei (2008). "Historical development of cardiopulmonary bypass in Minnesota". In Glenn P. Gravlee (ed.). Cardiopulmonary Bypass: Principles and Practice (Online). Lippincott Williams & Wilkins. pp. 11–18. ISBN 9780781768153. Retrieved 3 February 2014.