Talk:Neuraminidase: Difference between revisions
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== '''Q: Can [[N1..N9]] be used [[directly]] as a flu [[vaccine]] (with a promoter) ?''' == |
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'''IF''' |
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(1) there are a limited number of types of Neuraminidases (9 according to the article), |
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(2) if at least one type of Neuraminidases is present on every flu viron, |
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(3) if Neuraminidases subtypes (ex : N2) can be specifically recognized |
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as antigens by the immune system, and |
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(4) the immugenic epitopes on each Neuraminidases subtype are reasonably |
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well conserved over various flu virus mutations, |
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'''then''' |
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can '''vaccines''' be developped that '''DIRECTLY target Neuraminidases ''' - |
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(eg. a cocktail of N1, N2, N3..N9 with a promoter) to encourage |
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an immune response that is '''not diffusely aimed''' at a broad range |
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of viral antigens, but - rather - that is '''focussed''' on |
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a limited number (9) of more widely '''conserved''' antigens ? |
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Does anyone have information on this ? |
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Regards, |
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[[User:129.78.64.100|129.78.64.100]] 09:35, 20 February 2007 (UTC) G. Holt |
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(Please let me know at : ghol7955@gmp.usyd.edu.au |
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(Please don't spam me though!) |
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Thank you! |
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) |