Beta-phosphoglucomutase: Difference between revisions
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{{Correct title|reason=IUBMB Accepted Name|β-Phosphoglucomutase}} |
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{{enzyme |
{{enzyme |
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| Name = |
| Name = β-Phosphoglucomutase |
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| EC_number = 5.4.2.6 |
| EC_number = 5.4.2.6 |
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| CAS_number = 68651-99-0 |
| CAS_number = 68651-99-0 |
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In [[enzymology]], a ''' |
In [[enzymology]], a '''β-phosphoglucomutase''' ({{EnzExplorer|5.4.2.6}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]] |
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:β-D-glucose 1-phosphate <math>\rightleftharpoons</math> β-D-glucose 6-phosphate |
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Hence, this enzyme has one [[substrate (biochemistry)|substrate]], [[ |
Hence, this enzyme has one [[substrate (biochemistry)|substrate]], [[β-D-glucose 1-phosphate]], and one [[product (chemistry)|product]], [[β-D-glucose 6-phosphate]]. |
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This enzyme belongs to the family of [[isomerase]]s, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. The [[List of enzymes|systematic name]] of this enzyme class is '''beta-D-glucose 1,6-phosphomutase'''. This enzyme participates in [[starch and sucrose metabolism]]. |
This enzyme belongs to the family of [[isomerase]]s, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. The [[List of enzymes|systematic name]] of this enzyme class is '''beta-D-glucose 1,6-phosphomutase'''. This enzyme participates in [[starch and sucrose metabolism]]. |
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Revision as of 11:04, 5 July 2022
| β-Phosphoglucomutase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 5.4.2.6 | ||||||||
| CAS no. | 68651-99-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a β-phosphoglucomutase (EC 5.4.2.6) is an enzyme that catalyzes the chemical reaction
- β-D-glucose 1-phosphate β-D-glucose 6-phosphate
Hence, this enzyme has one substrate, β-D-glucose 1-phosphate, and one product, β-D-glucose 6-phosphate.
This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. The systematic name of this enzyme class is beta-D-glucose 1,6-phosphomutase. This enzyme participates in starch and sucrose metabolism.
Structural studies
20 structures have been solved for this enzyme PDB. Some of the accession codes are 1LVH, 1O03, 1O08, 1Z4N, 1Z4O, and 1ZOL. Most of these structures detail metal fluoride analogue complexes which are used to mimic different states along the reaction coordinate.
References
- Ben-Zvi R, Schramm M (1961). "A phosphoglucomutase specific for beta-glucose 1-phosphate". J. Biol. Chem. 236: 2186–2189.
- Boyer PD, ed. (1972). The Enzymes. Vol. 6 (3rd ed.). pp. 407–477.
