Mir-449 microRNA precursor family: Difference between revisions
Content deleted Content added
No edit summary Tag: Reverted |
No edit summary Tag: Reverted |
||
| Line 27: | Line 27: | ||
}} |
}} |
||
In molecular biology '''mir-449 microRNA''' is a short [[non-coding RNA|RNA]] molecule. [[MicroRNA]]s function to regulate the expression levels of other genes by several mechanisms. |
In molecular biology '''mir-449 microRNA''' is a short [[non-coding RNA|RNA]] molecule. [[MicroRNA]]s function to regulate the expression levels of other genes by several mechanisms. AA genotype of rs10061133 in mir-449b seems to confer protection against B-cell acute lymphoblastic leukemia in children <ref name=miRNAs_ALL>{{cite journal|vauthors= Kyriakidis I, Kyriakidis K, Tsezou A|title= MicroRNAs and the Diagnosis of Childhood Acute Lymphoblastic Leukemia: Systematic Review, Meta-Analysis and Re-Analysis with Novel Small RNA-Seq Tools | journal = Cancers | volume = 14 | issue = 16 | pages = 3976 | date = August 2022 | doi = 10.3390/cancers14163976 }}</ref>. |
||
== See also == |
== See also == |
||
Revision as of 14:16, 19 August 2022
| mir-449 | |
|---|---|
| Identifiers | |
| Symbol | mir-449 |
| Rfam | RF00711 |
| miRBase family | MIPF0000133 |
| Other data | |
| RNA type | microRNA |
| Domain(s) | Eukaryota; |
| PDB structures | PDBe |
In molecular biology mir-449 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. AA genotype of rs10061133 in mir-449b seems to confer protection against B-cell acute lymphoblastic leukemia in children [1].
See also
References
- ^ Kyriakidis I, Kyriakidis K, Tsezou A (August 2022). "MicroRNAs and the Diagnosis of Childhood Acute Lymphoblastic Leukemia: Systematic Review, Meta-Analysis and Re-Analysis with Novel Small RNA-Seq Tools". Cancers. 14 (16): 3976. doi:10.3390/cancers14163976.
{{cite journal}}: CS1 maint: unflagged free DOI (link)
Further reading
- Buurman R, Gürlevik E, Schäffer V, Eilers M, Sandbothe M, Kreipe H, Wilkens L, Schlegelberger B, Kühnel F, Skawran B (September 2012). "Histone deacetylases activate hepatocyte growth factor signaling by repressing microRNA-449 in hepatocellular carcinoma cells". Gastroenterology. 143 (3): 811–820.e15. doi:10.1053/j.gastro.2012.05.033. PMID 22641068.
- Bao J, Li D, Wang L, Wu J, Hu Y, Wang Z, Chen Y, Cao X, Jiang C, Yan W, Xu C (June 2012). "MicroRNA-449 and microRNA-34b/c function redundantly in murine testes by targeting E2F transcription factor-retinoblastoma protein (E2F-pRb) pathway". The Journal of Biological Chemistry. 287 (26): 21686–98. doi:10.1074/jbc.M111.328054. PMC 3381132. PMID 22570483.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - Ma YY, Tao HQ (April 2012). "Microribonucleic acids and gastric cancer". Cancer Science. 103 (4): 620–5. doi:10.1111/j.1349-7006.2011.02185.x. PMID 22168593.
- Jungebluth P, Alici E, Baiguera S, Blomberg P, Bozóky B, Crowley C, Einarsson O, Gudbjartsson T, Le Guyader S, Henriksson G, Hermanson O, Juto JE, Leidner B, Lilja T, Liska J, Luedde T, Lundin V, Moll G, Roderburg C, Strömblad S, Sutlu T, Watz E, Seifalian A, Macchiarini P (December 2011). "Tracheobronchial transplantation with a stem-cell-seeded bioartificial nanocomposite: a proof-of-concept study". Lancet. 378 (9808): 1997–2004. doi:10.1016/S0140-6736(11)61715-7. PMID 22119609.
- Lizé M, Klimke A, Dobbelstein M (September 2011). "MicroRNA-449 in cell fate determination" (PDF). Cell Cycle. 10 (17): 2874–82. doi:10.4161/cc.10.17.17181. PMID 21857159.
- Marcet B, Chevalier B, Coraux C, Kodjabachian L, Barbry P (September 2011). "MicroRNA-based silencing of Delta/Notch signaling promotes multiple cilia formation". Cell Cycle. 10 (17): 2858–64. doi:10.4161/cc.10.17.17011. PMID 21857154.
- Buechner J, Tømte E, Haug BH, Henriksen JR, Løkke C, Flægstad T, Einvik C (July 2011). "Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma". British Journal of Cancer. 105 (2): 296–303. doi:10.1038/bjc.2011.220. PMC 3142803. PMID 21654684.
- Marcet B, Chevalier B, Luxardi G, Coraux C, Zaragosi LE, Cibois M, Robbe-Sermesant K, Jolly T, Cardinaud B, Moreilhon C, Giovannini-Chami L, Nawrocki-Raby B, Birembaut P, Waldmann R, Kodjabachian L, Barbry P (June 2011). "Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway". Nature Cell Biology. 13 (6): 693–9. doi:10.1038/ncb2241. PMID 21602795.
- Chevalier B, Adamiok A, Mercey O, Revinski DR, Zaragosi LE, Pasini A, Kodjabachian L, Barbry P, Marcet B (September 2015). ""miR-34/449 control apical actin network formation during multiciliogenesis through small GTPase pathways"". Nature Communications. 18 (6): 8386. doi:10.1038/ncomms9386. PMID 26381333.
- Mercey O, Popa A, Cavard A, Paquet A, Chevalier B, Pons N, Magnone V, Zangari J, Brest P, Zaragosi LE, Ponzio G, Lebrigand K, Barbry P, Marcet B (March 2017). ""Characterizing isomiR variants within the microRNA-34/449 family"". FEBS Letters. 591 (5): 693–705. doi:10.1002/1873-3468.12595. PMID 28192603.
- Bou Kheir T, Futoma-Kazmierczak E, Jacobsen A, Krogh A, Bardram L, Hother C, Grønbæk K, Federspiel B, Lund AH, Friis-Hansen L (March 2011). "miR-449 inhibits cell proliferation and is down-regulated in gastric cancer". Molecular Cancer. 10: 29. doi:10.1186/1476-4598-10-29. PMC 3070685. PMID 21418558.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - Ma L, Li N, He X, Zhang Q (February 2011). "[miR-449b and miR-34c on inducing down-regulation of cell cycle-related proteins and cycle arrests in SKOV3-ipl cell, an ovarian cancer cell line]". Beijing Da Xue Xue Bao. Yi Xue Ban = Journal of Peking University. Health Sciences. 43 (1): 129–33. PMID 21321636.
- Wang XY, Wu MH, Liu F, Li Y, Li N, Li GY, Shen SR (December 2010). "Differential miRNA expression and their target genes between NGX6-positive and negative colon cancer cells". Molecular and Cellular Biochemistry. 345 (1–2): 283–90. doi:10.1007/s11010-010-0582-7. PMID 20859756.
- Feng M, Yu Q (January 2010). "miR-449 regulates CDK-Rb-E2F1 through an auto-regulatory feedback circuit". Cell Cycle. 9 (2): 213–4. doi:10.4161/cc.9.2.10502. PMID 20046097.
- Campanini ML, Colli LM, Paixao BM, Cabral TP, Amaral FC, Machado HR, Neder LS, Saggioro F, Moreira AC, Antonini SR, de Castro M (August 2010). "CTNNB1 gene mutations, pituitary transcription factors, and MicroRNA expression involvement in the pathogenesis of adamantinomatous craniopharyngiomas". Hormones & Cancer. 1 (4): 187–96. doi:10.1007/s12672-010-0041-7. PMID 21761366.
- Lizé M, Pilarski S, Dobbelstein M (March 2010). "E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis". Cell Death and Differentiation. 17 (3): 452–8. doi:10.1038/cdd.2009.188. PMID 19960022.
- Greco S, De Simone M, Colussi C, Zaccagnini G, Fasanaro P, Pescatori M, Cardani R, Perbellini R, Isaia E, Sale P, Meola G, Capogrossi MC, Gaetano C, Martelli F (October 2009). "Common micro-RNA signature in skeletal muscle damage and regeneration induced by Duchenne muscular dystrophy and acute ischemia". FASEB Journal. 23 (10): 3335–46. doi:10.1096/fj.08-128579. PMID 19528256.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - Iliopoulos D, Bimpaki EI, Nesterova M, Stratakis CA (April 2009). "MicroRNA signature of primary pigmented nodular adrenocortical disease: clinical correlations and regulation of Wnt signaling". Cancer Research. 69 (8): 3278–82. doi:10.1158/0008-5472.CAN-09-0155. PMC 3124768. PMID 19351815.
- Wu W, Lin Z, Zhuang Z, Liang X (February 2009). "Expression profile of mammalian microRNAs in endometrioid adenocarcinoma". European Journal of Cancer Prevention. 18 (1): 50–5. doi:10.1097/CEJ.0b013e328305a07a. PMID 19077565.