[[Holger Rune]] defeated the defending champion [[Novak Djokovic]]<ref>{{Cite web|date=7 November 2021|title=Djokovic Wins Record 37th Masters 1000 Crown|url=https://www.atptour.com/en/news/djokovic-medvedev-paris-2021-sunday-final|url-status=live|access-date=7 November 2021|publisher=[[Association of Tennis Professionals]]|archive-url=https://web.archive.org/web/20211107180759/https://www.atptour.com/en/news/djokovic-medvedev-paris-2021-sunday-final |archive-date=2021-11-07}}</ref> in the final, 3–6, 6–3, 7–5 to win the singles tennis title at the 2022 Paris Masters. It was his maiden [[ATP Tour Masters 1000|Masters 1000]] title, and he saved three match points en route, in the first round against [[Stan Wawrinka]].<ref>{{cite web|url=https://www.atptour.com/en/news/rune-wawrinka-paris-2022-tuesday|title=Red-Hot Rune Saves 3 MPs To Stun Stan|date=1 November 2022}}</ref> Rune made his top-10 debut in the [[ATP rankings]] with the win, and he defeated five top-10 players en route to the title.<ref>{{cite web|url=https://www.atptour.com/en/news/djokovic-rune-paris-2022-sunday-final|date=6 November 2022|title=Rune Rules In Paris! Dane Stuns Djokovic|access-date=6 November 2022|publisher=[[Association of Tennis Professionals]]}}</ref> This was Rune's fourth final in a row, and his third title. He became the second teenager to win a Masters 1000 title in the 2022 season, after [[Carlos Alcaraz]] at [[2022 Miami Open – Men's singles|Miami]] and [[2022 Mutua Madrid Open – Men's singles|Madrid]]. Rune is the first Scandinavian man to win the Masters 1000 title since [[Thomas Enqvist]] in the [[2000 Cincinnati Masters − Singles|2000 Cincinnati Masters]].
[[Holger Rune]] defeated the defending champion [[Novak Djokovic]]<ref>{{Cite web|date=7 November 2021|title=Djokovic Wins Record 37th Masters 1000 Crown|url=https://www.atptour.com/en/news/djokovic-medvedev-paris-2021-sunday-final|url-status=live|access-date=7 November 2021|publisher=[[Association of Tennis Professionals]]|archive-url=https://web.archive.org/web/20211107180759/https://www.atptour.com/en/news/djokovic-medvedev-paris-2021-sunday-final |archive-date=2021-11-07}}</ref> in the final, 3–6, 6–3, 7–5 to win the singles tennis title at the 2022 Paris Masters. It was his maiden [[ATP Tour Masters 1000|Masters 1000]] title, and he saved three match points en route, in the first round against [[Stan Wawrinka]].<ref>{{cite web|url=https://www.atptour.com/en/news/rune-wawrinka-paris-2022-tuesday|title=Red-Hot Rune Saves 3 MPs To Stun Stan|date=1 November 2022}}</ref> Rune made his top-10 debut in the [[ATP rankings]] with the win, and he defeated five top-10 players en route to the title.<ref>{{cite web|url=https://www.atptour.com/en/news/djokovic-rune-paris-2022-sunday-final|date=6 November 2022|title=Rune Rules In Paris! Dane Stuns Djokovic|access-date=6 November 2022|publisher=[[Association of Tennis Professionals]]}}</ref> This was Rune's fourth final in a row, and his third title. He became the second teenager to win a Masters 1000 title in the 2022 season, after [[Carlos Alcaraz]] at [[2022 Miami Open – Men's singles|Miami]] and [[2022 Mutua Madrid Open – Men's singles|Madrid]]. Rune was the first Scandinavian man to win the Masters 1000 title since [[Thomas Enqvist]] in the [[2000 Cincinnati Masters – Singles|2000 Cincinnati Masters]].
This tournament marked the final professional appearance of former world No. 6 [[Gilles Simon]];<ref>{{cite web|url=https://www.atptour.com/en/news/murray-simon-paris-2022-tuesday|title=Back From The Brink, Simon Lives On With Paris Victory|date=31 October 2022}}</ref> he lost in the third round to [[Félix Auger-Aliassime]].<ref>{{cite web|url=https://www.atptour.com/en/news/gilles-simon-paris-2022-retirement-feature|title=After A Final Magical Moment, Gilles Simon Bids Adieu|date=3 November 2022}}</ref>
This tournament marked the final professional appearance of former world No. 6 [[Gilles Simon]];<ref>{{cite web|url=https://www.atptour.com/en/news/murray-simon-paris-2022-tuesday|title=Back From The Brink, Simon Lives On With Paris Victory|date=31 October 2022}}</ref> he lost in the third round to [[Félix Auger-Aliassime]].<ref>{{cite web|url=https://www.atptour.com/en/news/gilles-simon-paris-2022-retirement-feature|title=After A Final Magical Moment, Gilles Simon Bids Adieu|date=3 November 2022}}</ref>
Holger Rune defeated the defending champion Novak Djokovic[1] in the final, 3–6, 6–3, 7–5 to win the singles tennis title at the 2022 Paris Masters. It was his maiden Masters 1000 title, and he saved three match points en route, in the first round against Stan Wawrinka.[2] Rune made his top-10 debut in the ATP rankings with the win, and he defeated five top-10 players en route to the title.[3] This was Rune's fourth final in a row, and his third title. He became the second teenager to win a Masters 1000 title in the 2022 season, after Carlos Alcaraz at Miami and Madrid. Rune was the first Scandinavian man to win the Masters 1000 title since Thomas Enqvist in the 2000 Cincinnati Masters.
Auger-Aliassime was attempting to win his fourth tournament in as many weeks, but lost in the semifinals to Rune in a rematch of the Swiss Indoors final from the previous week, snapping his winning streak at 16 matches.[6]
Rafael Nadal and Alcaraz were both in contention for the ATP No. 1 singles ranking at the beginning of the tournament. Following Nadal's second round loss to Tommy Paul, Alcaraz retained the No. 1 ranking.[7]
Seeds
The top eight seeds received a bye into the second round.