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Peer-reviewed results published in [[JAMA]] of Phase III trials in [[United Arab Emirates]] and [[Bahrain]] showed BBIBP-CorV 78.1% effective against symptomatic cases and 100% against severe cases (21 cases in vaccinated group vs. 95 cases in placebo group).<ref name="jama.2021.8565">{{cite journal|last1=Kaabi|first1=Nawal Al|last2=Zhang|first2=Yuntao|last3=Xia|first3=Shengli|last4=Yang|first4=Yunkai|last5=Qahtani|first5=Manaf M. Al|last6=Abdulrazzaq|first6=Najiba|last7=Nusair|first7=Majed Al|last8=Hassany|first8=Mohamed|last9=Jawad|first9=Jaleela S.|last10=Abdalla|first10=Jehad|last11=Hussein|first11=Salah Eldin|display-authors=3|date=May 26, 2021|title=Effect of 2 Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in Adults: A Randomized Clinical Trial|journal=JAMA|language=en|doi=10.1001/jama.2021.8565|first29=Yuxiu|first22=Yang|first16=Wei|last17=Lai|first17=Bonan|last18=Chen|first18=Wei|last19=Huang|first19=Shihe|last20=Wang|first20=Qian|last21=Yang|first21=Tian|last22=Liu|last23=Ma|last29=Zhao|last30=Jiang|first14=Xinguo|last24=Hussain|first24=Zaidoon M.|last25=Khan|first25=Tehmina|last26=Fasihuddin|first26=Mohammed Saifuddin|last27=You|first27=Wangyang|last28=Xie|first28=Zhiqiang|last16=Wang|last31=Zhao|first15=Xuqin|last37=Zaher|last15=Yang|first37=Walid Abbas|last32=Zhang|first32=Yanbo|last33=Mahmoud|first33=Sally|last34=ElTantawy|first34=Islam|last35=Xiao|first35=Peng|last36=Koshy|first36=Ashish|first38=Hui|first30=Zhiwei|last38=Wang|last39=Duan|first39=Kai|last40=Pan|first40=An|last41=Yang|first41=Xiaoming|last14=Li|first13=Maysoon Al|last13=Karam|first12=Shamma K. Al|last12=Mazrouei|first31=Guoqing|first23=Rui|volume=326|issue=1|pages=35–45|pmid=34037666|pmc=8156175|doi-access=free}}</ref> In December 2020, the UAE previously announced interim results showing 86% efficacy.<ref>{{Cite web|title=UAE: Ministry of Health announces 86 per cent vaccine efficacy|url=https://gulfnews.com/uae/health/uae-ministry-of-health-announces-86-per-cent-vaccine-efficacy-1.1607490555571|access-date=2020-12-13|website=gulfnews.com|language=en}}</ref> While mRNA vaccines like the [[Pfizer–BioNTech COVID-19 vaccine]] and [[mRNA-1273]] showed higher efficacy of over 90%, those present distribution challenges for some nations as they require deep-freeze facilities and trucks. BIBP-CorV could be transported and stored at normal refrigerated temperatures.<ref name=":62">{{Cite news|date=2020-12-09|title=China State-Backed Covid Vaccine Has 86% Efficacy, UAE Says|language=en|work=Bloomberg.com|url=https://www.bloomberg.com/news/articles/2020-12-09/uae-says-sinopharm-vaccine-has-86-efficacy-against-covid-19|access-date=2020-12-09}}</ref> |
Peer-reviewed results published in [[JAMA]] of Phase III trials in [[United Arab Emirates]] and [[Bahrain]] showed BBIBP-CorV 78.1% effective against symptomatic cases and 100% against severe cases (21 cases in vaccinated group vs. 95 cases in placebo group).<ref name="jama.2021.8565">{{cite journal|last1=Kaabi|first1=Nawal Al|last2=Zhang|first2=Yuntao|last3=Xia|first3=Shengli|last4=Yang|first4=Yunkai|last5=Qahtani|first5=Manaf M. Al|last6=Abdulrazzaq|first6=Najiba|last7=Nusair|first7=Majed Al|last8=Hassany|first8=Mohamed|last9=Jawad|first9=Jaleela S.|last10=Abdalla|first10=Jehad|last11=Hussein|first11=Salah Eldin|display-authors=3|date=May 26, 2021|title=Effect of 2 Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in Adults: A Randomized Clinical Trial|journal=JAMA|language=en|doi=10.1001/jama.2021.8565|first29=Yuxiu|first22=Yang|first16=Wei|last17=Lai|first17=Bonan|last18=Chen|first18=Wei|last19=Huang|first19=Shihe|last20=Wang|first20=Qian|last21=Yang|first21=Tian|last22=Liu|last23=Ma|last29=Zhao|last30=Jiang|first14=Xinguo|last24=Hussain|first24=Zaidoon M.|last25=Khan|first25=Tehmina|last26=Fasihuddin|first26=Mohammed Saifuddin|last27=You|first27=Wangyang|last28=Xie|first28=Zhiqiang|last16=Wang|last31=Zhao|first15=Xuqin|last37=Zaher|last15=Yang|first37=Walid Abbas|last32=Zhang|first32=Yanbo|last33=Mahmoud|first33=Sally|last34=ElTantawy|first34=Islam|last35=Xiao|first35=Peng|last36=Koshy|first36=Ashish|first38=Hui|first30=Zhiwei|last38=Wang|last39=Duan|first39=Kai|last40=Pan|first40=An|last41=Yang|first41=Xiaoming|last14=Li|first13=Maysoon Al|last13=Karam|first12=Shamma K. Al|last12=Mazrouei|first31=Guoqing|first23=Rui|volume=326|issue=1|pages=35–45|pmid=34037666|pmc=8156175|doi-access=free}}</ref> In December 2020, the UAE previously announced interim results showing 86% efficacy.<ref>{{Cite web|title=UAE: Ministry of Health announces 86 per cent vaccine efficacy|url=https://gulfnews.com/uae/health/uae-ministry-of-health-announces-86-per-cent-vaccine-efficacy-1.1607490555571|access-date=2020-12-13|website=gulfnews.com|language=en}}</ref> While mRNA vaccines like the [[Pfizer–BioNTech COVID-19 vaccine]] and [[mRNA-1273]] showed higher efficacy of over 90%, those present distribution challenges for some nations as they require deep-freeze facilities and trucks. BIBP-CorV could be transported and stored at normal refrigerated temperatures.<ref name=":62">{{Cite news|date=2020-12-09|title=China State-Backed Covid Vaccine Has 86% Efficacy, UAE Says|language=en|work=Bloomberg.com|url=https://www.bloomberg.com/news/articles/2020-12-09/uae-says-sinopharm-vaccine-has-86-efficacy-against-covid-19|access-date=2020-12-09}}</ref> |
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BBIBP-CorV is being used in vaccination campaigns by certain countries in Asia,<ref name=":122">{{Cite news|date=2020-12-31|title=China gives its first COVID-19 vaccine approval to Sinopharm|work=Reuters|url=https://www.reuters.com/article/us-health-coronavirus-vaccine-china-idUSKBN29505P |
BBIBP-CorV is being used in vaccination campaigns by certain countries in Asia,<ref name=":122">{{Cite news|date=2020-12-31|title=China gives its first COVID-19 vaccine approval to Sinopharm|work=Reuters|url=https://www.reuters.com/article/us-health-coronavirus-vaccine-china-idUSKBN29505P|access-date=2020-12-31|vauthors=Liu R}}</ref><ref name=":26">{{Cite web|last=Turak|first=Natasha|date=2021-01-18|title=The UAE is on track to have half its population vaccinated by the end of March|url=https://www.cnbc.com/2021/01/18/uae-on-track-to-vaccinate-half-its-population-by-end-of-march-.html|access-date=2021-01-21|website=CNBC}}</ref><ref name=":72">{{Cite web|last=Dawn.com|date=2021-02-02|title=PM Imran kicks off Pakistan's Covid-19 vaccination drive|url=https://www.dawn.com/news/1605089|access-date=2021-02-03|website=DAWN.COM|language=en}}</ref> Africa,<ref name=":92">{{Cite news|last1=Waly|first1=Mohamed|last2=Eltahir|first2=Nafisa|editor-last=Richardson|editor-first=Alex|date=2021-01-24|title=Sisi says Egypt to begin COVID-19 vaccinations on Sunday|work=[[Reuters]]|location=Cairo|url=https://www.reuters.com/article/us-health-coronavirus-egypt-vaccinations-idUSKBN29T05N|access-date=2023-01-19}}</ref><ref name=":152">{{Cite web|last=Dumpis|first=Toms|date=2021-01-27|title=Morocco Receives Half a Million Doses of Chinese Sinopharm Vaccine|url=https://www.moroccoworldnews.com/2021/01/333436/morocco-receives-half-a-million-doses-of-chinese-sinopharm-vaccine/|access-date=2021-01-28|website=Morocco World News}}</ref><ref name=":112">{{Cite web|date=2021-02-18|title=Zimbabwe starts administering China's Sinopharm vaccines|url=https://www.thestar.com/news/world/africa/2021/02/18/zimbabwe-starts-administering-chinas-sinopharm-vaccines.html|access-date=2021-02-20|website=thestar.com|language=en}}</ref> South America,<ref name=":252">{{Cite web|title=Argentina autoriza la vacuna china Sinopharm para mayores de 60 años|url=https://www.elcomercio.com/actualidad/argentina-vacuna-china-sinopharm-adultos.html|access-date=2021-03-26|website=El Comercio}}</ref><ref name=":162">{{Cite news|last=Aquino|first=Marco|date=2021-02-10|title='The best shield': Peru launches inoculation drive with Sinopharm vaccine|language=en|work=Reuters|url=https://www.reuters.com/article/us-health-coronavirus-peru-vaccine-idUSKBN2AA03U|access-date=2021-02-10}}</ref><ref name=":232">{{Cite web|title=Bolivia begins inoculation with Sinopharm jabs {{!}} The Star|url=https://www.thestar.com.my/aseanplus/aseanplus-news/2021/02/26/bolivia-begins-inoculation-with-sinopharm-jabs|access-date=2021-02-28|website=www.thestar.com.my}}</ref> and Europe.<ref name=":172">{{Cite web|title=Serbia Becomes First European Nation To Use China's Sinopharm Vaccine|url=https://www.rferl.org/a/serbia-covid-vaccine-china-sinopharm/31053091.html|access-date=2021-01-21|website=RadioFreeEurope/RadioLiberty}}</ref><ref name=":212">{{Cite web|date=2021-02-24|title=Hungary first EU nation to use China's Sinopharm vaccine against COVID|url=https://www.euronews.com/2021/02/24/hungary-becomes-first-eu-nation-to-use-china-s-sinopharm-vaccine-against-covid-19|access-date=2021-02-26|website=euronews|language=en}}</ref><ref name=":242">{{Cite web|date=2021-03-15|title=Belarus begins COVID-19 vaccinations with Chinese shots|url=https://eng.belta.by/society/view/belarus-begins-covid-19-vaccinations-with-chinese-shots-138222-2021/|access-date=2021-03-16|website=eng.belta.by|language=en-EN}}</ref> Sinopharm expects to produce one billion doses of BBIBP-CorV in 2021.<ref name=":222">{{Cite web|date=2021-02-05|title=Which companies will likely produce the most COVID-19 vaccine in 2021?|url=https://www.pharmaceuticalprocessingworld.com/which-companies-will-likely-produce-the-most-covid-19-vaccine-in-2021/|access-date=2021-02-28|website=Pharmaceutical Processing World|language=en-US}}</ref> On 7 May 2021, the [[World Health Organization]] approved the vaccine for emergency use<ref name="WHOEUA">{{cite news|last=Taylor|first=Adam|date=7 May 2021|title=WHO grants emergency use authorization for Chinese-made Sinopharm coronavirus vaccine|newspaper=[[The Washington Post]]|url=https://www.washingtonpost.com/world/2021/05/07/who-sinopharm-emergency-use/|access-date=7 May 2021}}</ref> and Sinopharm later signed purchase agreements for 170 million doses from [[COVAX]].<ref name=":282">{{Cite web|date=2021-07-12|title=Chinese drugmakers agree to supply more than half a billion vaccines to COVAX|url=https://www.reuters.com/world/gavi-signs-covid-19-vaccine-supply-deals-with-sinovac-sinopharm-covax-2021-07-12/|access-date=2021-07-13|website=Reuters}}</ref> |
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The similarly named Sinopharm WIBP COVID-19 vaccine is also an inactivated virus vaccine.{{cn|date=October 2022}} |
The similarly named Sinopharm WIBP COVID-19 vaccine is also an inactivated virus vaccine.{{cn|date=October 2022}} |
Revision as of 18:06, 27 September 2023
39°58′29″N 116°20′24″E / 39.9747°N 116.3401°E
Sinopharm | |||||||
Company type | state-owned enterprise | ||||||
Founded | November 26, 1998 | ||||||
Headquarters | 20 Zhichun Road, Haidian District, Beijing , China | ||||||
Area served | China, exported worldwide | ||||||
Key people | Liu Jingzhen (Chairman & Chinese Communist Party Committee Secretary)[1][2] | ||||||
Revenue | CN¥247.110 billion (2014) | ||||||
CN¥8.758 billion (2014) | |||||||
CN¥2.705 billion (2014) | |||||||
Total assets | CN¥199.192 billion (2014) | ||||||
Total equity | CN¥31.944 billion (2014) | ||||||
Owner | Chinese central government (100%) | ||||||
Parent | SASAC of the State Council | ||||||
Subsidiaries |
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Chinese name | |||||||
Simplified Chinese | 中国医药集团总公司 | ||||||
Traditional Chinese | 中國醫藥集團總公司 | ||||||
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short Chinese name | |||||||
Simplified Chinese | 国药集团 | ||||||
Traditional Chinese | 國藥集團 | ||||||
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Footnotes / references in a consolidated basis; equity and profit excluded minority interests; in Chinese Accounting Standards[3] |
China National Pharmaceutical Group Corporation (CNPGC), commonly referred to as Sinopharm, is a Chinese state-owned enterprise. The corporation was the indirect major shareholder of publicly traded companies Sinopharm Group (SEHK: 1099, via a 51–49 joint venture, Sinopharm Industrial Investment, with Fosun Pharmaceutical), China Traditional Chinese Medicine (SEHK: 570, mostly via Sinopharm Group Hongkong Co., Ltd.),[4] Shanghai Shyndec Pharmaceutical (SSE: 600420, via a wholly owned research institute based in Shanghai), and Beijing Tiantan Biological Products (SSE: 600161, via China National Biotec Group).
China National Pharmaceutical Group was supervised by the State-owned Assets Supervision and Administration Commission of the State Council.[5]
Sinopharm was ranked 109th in the 2021 Fortune Global 500 list.[6]
History
Sinopharm was founded as China National Pharmaceutical Group Corporation (Chinese: 中国医药集团总公司) on November 26, 1998, as a holding company for China National Pharmaceutical Corporation, China National Pharmaceutical Industry Corporation (Chinese: 中国医药工业公司), China National Pharmaceutical Foreign Trade Corp. (Chinese: 中国医药对外贸易公司) and China National Medical Device (Chinese: 中国医疗器械工业公司). In 2009 it was merged with China National Biotec Group (Chinese: 中国生物技术集团公司).[citation needed]
Its subsidiary Wuhan Institute of Biological Products was fined for selling 400,520 ineffective DPT vaccines in November 2017.[7]
COVID-19 vaccines
The Sinopharm BIBP COVID-19 vaccine, also known as BBIBP-CorV,[8] the Sinopharm COVID-19 vaccine,[9] or BIBP vaccine,[9][10][11] is one of two inactivated virus COVID-19 vaccines developed by Sinopharm. It completed Phase III trials in Argentina, Bahrain, Egypt, Morocco, Pakistan, Peru, and the United Arab Emirates (UAE) with over 60,000 participants.[12] BBIBP-CorV shares similar technology with CoronaVac and BBV152, other inactivated virus vaccines for COVID-19.[13]
Peer-reviewed results published in JAMA of Phase III trials in United Arab Emirates and Bahrain showed BBIBP-CorV 78.1% effective against symptomatic cases and 100% against severe cases (21 cases in vaccinated group vs. 95 cases in placebo group).[14] In December 2020, the UAE previously announced interim results showing 86% efficacy.[15] While mRNA vaccines like the Pfizer–BioNTech COVID-19 vaccine and mRNA-1273 showed higher efficacy of over 90%, those present distribution challenges for some nations as they require deep-freeze facilities and trucks. BIBP-CorV could be transported and stored at normal refrigerated temperatures.[16]
BBIBP-CorV is being used in vaccination campaigns by certain countries in Asia,[17][18][19] Africa,[20][21][22] South America,[23][24][25] and Europe.[26][27][28] Sinopharm expects to produce one billion doses of BBIBP-CorV in 2021.[29] On 7 May 2021, the World Health Organization approved the vaccine for emergency use[30] and Sinopharm later signed purchase agreements for 170 million doses from COVAX.[31]
The similarly named Sinopharm WIBP COVID-19 vaccine is also an inactivated virus vaccine.[citation needed]
See also
References
- ^ "中国医药集团有限公司主要领导调整" (in Chinese). Sinopharm.
- ^ "Liu Jingzhen". Bloomberg.
- ^ "中国医药集团总公司2016年度第一期超短期融资券发行披露材料" [Pospectus of 2016 (batch 1) Ultra-short-term financing of Sinopharm]. Sinopharm (in Chinese). Shanghai Clearing House. 19 January 2016. Retrieved 22 November 2016.
- ^ "2015 Annual Report" (PDF). China Traditional Chinese Medicine. Hong Kong Stock Exchange. 28 April 2016. Retrieved 22 November 2016.
- ^ "央企名录 (List of Central SOEs)". Official website of SASAC (in Chinese). Retrieved 3 March 2016.
- ^ "Global 500".
- ^ "Chinese President Xi Jinping orders crackdown over 'appalling' vaccine scandal". South China Morning Post. 23 July 2018. Retrieved 29 November 2018.
- ^ Xia S, Zhang Y, Wang Y, Wang H, Yang Y, Gao GF, et al. (January 2021). "Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBIBP-CorV: a randomised, double-blind, placebo-controlled, phase 1/2 trial". The Lancet. Infectious Diseases. 21 (1): 39–51. doi:10.1016/s1473-3099(20)30831-8. PMC 7561304. PMID 33069281.
- ^ a b "The Sinopharm COVID-19 vaccine: What you need to know". World Health Organization. 10 May 2021. Retrieved 5 July 2021.
- ^ Nguyen S (5 June 2021). "Coronavirus: Vietnam approves Sinopharm's vaccine, but will people take it?". South China Morning Post. Retrieved 5 July 2021.
- ^ Lahiri T, Li J (16 June 2021). "What we now know about the efficacy of China's Covid-19 vaccines". Quartz. Retrieved 5 July 2021.
- ^ Liu, Roxanne; Munroe, Tony (2020-11-19). Sarkar, Himani (ed.). "China Sinopharm's coronavirus vaccine taken by about a million people in emergency use". Reuters. Beijing. Retrieved 2023-01-19.
- ^ Corum, Jonathan; Zimmer, Carl (2021-04-26). "How the Sinopharm Vaccine Works". The New York Times. ISSN 0362-4331. Retrieved 2021-04-29.
- ^ Kaabi, Nawal Al; Zhang, Yuntao; Xia, Shengli; et al. (May 26, 2021). "Effect of 2 Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in Adults: A Randomized Clinical Trial". JAMA. 326 (1): 35–45. doi:10.1001/jama.2021.8565. PMC 8156175. PMID 34037666.
- ^ "UAE: Ministry of Health announces 86 per cent vaccine efficacy". gulfnews.com. Retrieved 2020-12-13.
- ^ "China State-Backed Covid Vaccine Has 86% Efficacy, UAE Says". Bloomberg.com. 2020-12-09. Retrieved 2020-12-09.
- ^ Liu R (2020-12-31). "China gives its first COVID-19 vaccine approval to Sinopharm". Reuters. Retrieved 2020-12-31.
- ^ Turak, Natasha (2021-01-18). "The UAE is on track to have half its population vaccinated by the end of March". CNBC. Retrieved 2021-01-21.
- ^ Dawn.com (2021-02-02). "PM Imran kicks off Pakistan's Covid-19 vaccination drive". DAWN.COM. Retrieved 2021-02-03.
- ^ Waly, Mohamed; Eltahir, Nafisa (2021-01-24). Richardson, Alex (ed.). "Sisi says Egypt to begin COVID-19 vaccinations on Sunday". Reuters. Cairo. Retrieved 2023-01-19.
- ^ Dumpis, Toms (2021-01-27). "Morocco Receives Half a Million Doses of Chinese Sinopharm Vaccine". Morocco World News. Retrieved 2021-01-28.
- ^ "Zimbabwe starts administering China's Sinopharm vaccines". thestar.com. 2021-02-18. Retrieved 2021-02-20.
- ^ "Argentina autoriza la vacuna china Sinopharm para mayores de 60 años". El Comercio. Retrieved 2021-03-26.
- ^ Aquino, Marco (2021-02-10). "'The best shield': Peru launches inoculation drive with Sinopharm vaccine". Reuters. Retrieved 2021-02-10.
- ^ "Bolivia begins inoculation with Sinopharm jabs | The Star". www.thestar.com.my. Retrieved 2021-02-28.
- ^ "Serbia Becomes First European Nation To Use China's Sinopharm Vaccine". RadioFreeEurope/RadioLiberty. Retrieved 2021-01-21.
- ^ "Hungary first EU nation to use China's Sinopharm vaccine against COVID". euronews. 2021-02-24. Retrieved 2021-02-26.
- ^ "Belarus begins COVID-19 vaccinations with Chinese shots". eng.belta.by. 2021-03-15. Retrieved 2021-03-16.
- ^ "Which companies will likely produce the most COVID-19 vaccine in 2021?". Pharmaceutical Processing World. 2021-02-05. Retrieved 2021-02-28.
- ^ Taylor, Adam (7 May 2021). "WHO grants emergency use authorization for Chinese-made Sinopharm coronavirus vaccine". The Washington Post. Retrieved 7 May 2021.
- ^ "Chinese drugmakers agree to supply more than half a billion vaccines to COVAX". Reuters. 2021-07-12. Retrieved 2021-07-13.