Talk:Sodium-glucose transport proteins: Difference between revisions
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http://us.boehringer-ingelheim.com/news_events/press_releases/press_release_archive/2014/08-01-14-fda-approves-jardiance-empagliflozin-tablets-reduce-blood-sugar-levels-adults-type-2-diabetes.html <small class="autosigned">— Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/162.134.56.6|162.134.56.6]] ([[User talk:162.134.56.6|talk]]) 17:52, 5 November 2014 (UTC)</small><!-- Template:Unsigned IP --> <!--Autosigned by SineBot--> |
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== Clarification needed: sodium depletion or rise in potassium? == |
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In "Function" section I read: |
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{{Talk quote box|sodium can deplete, so [[Sodium–hydrogen antiporter]] gets sodium into the cell to begin with.}} |
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but SGLT imports in the cell glucose and sodium, thus I see no reason for sodium depletion. |
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On the other hand, it is stated that [[Na+/K+ ATPase|Na<sup>+</sup>/K<sup>+</sup> ATPase]] exports sodium and imports potassium, thus I think the limiting factor should be rise in potassium concentration. |
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Someone with sufficient knowledge of this matter can clarify? [[User:Fornaeffe|Fornaeffe]] ([[User talk:Fornaeffe|talk]]) 16:00, 14 October 2024 (UTC) |
Revision as of 16:00, 14 October 2024
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Untitled
1 Aug 2014- Empagliflozin was approved (Jardiance) by the FDA for use in DMT2.
http://us.boehringer-ingelheim.com/news_events/press_releases/press_release_archive/2014/08-01-14-fda-approves-jardiance-empagliflozin-tablets-reduce-blood-sugar-levels-adults-type-2-diabetes.html — Preceding unsigned comment added by 162.134.56.6 (talk) 17:52, 5 November 2014 (UTC)
Clarification needed: sodium depletion or rise in potassium?
In "Function" section I read:
sodium can deplete, so Sodium–hydrogen antiporter gets sodium into the cell to begin with.
but SGLT imports in the cell glucose and sodium, thus I see no reason for sodium depletion.
On the other hand, it is stated that Na+/K+ ATPase exports sodium and imports potassium, thus I think the limiting factor should be rise in potassium concentration.
Someone with sufficient knowledge of this matter can clarify? Fornaeffe (talk) 16:00, 14 October 2024 (UTC)