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'''Stauffer [[syndrome]]''' is a constellation of [[sign (medicine)|sign]]s and [[symptom]]s of [[liver]] dysfunction that arise due to presence of [[renal cell carcinoma]]<ref>Stedman's Medical Dictionary. URL: [http://www.emedicine.com/asp/dictionary.asp?keyword=Stauffer+syndrome http://www.emedicine.com/asp/dictionary.asp?keyword=Stauffer+syndrome]. Accessed on: April 14, 2007.</ref> but are not due to tumour inflitration into the liver and/or intrinsic liver disease; it is a [[paraneoplastic syndrome]].<ref name=jakse>{{cite journal |author=Jakse G, Madersbacher H |title=[Stauffer's syndrome. Reversible hepatic dysfunction in renal cell carcinoma (author's transl)] |journal=Wien Klin Wochenschr |volume=90 |issue=8 |pages=268-70 |year=1978 |pmid=636440}}</ref>
'''Stauffer[woo-hoo. that's my last name] [[syndrome]]''' is a constellation of [[sign (medicine)|sign]]s and [[symptom]]s of [[liver]] dysfunction that arise due to presence of [[renal cell carcinoma]]<ref>Stedman's Medical Dictionary. URL: [http://www.emedicine.com/asp/dictionary.asp?keyword=Stauffer+syndrome http://www.emedicine.com/asp/dictionary.asp?keyword=Stauffer+syndrome]. Accessed on: April 14, 2007.</ref> but are not due to tumour inflitration into the liver and/or intrinsic liver disease; it is a [[paraneoplastic syndrome]].<ref name=jakse>{{cite journal |author=Jakse G, Madersbacher H |title=[Stauffer's syndrome. Reversible hepatic dysfunction in renal cell carcinoma (author's transl)] |journal=Wien Klin Wochenschr |volume=90 |issue=8 |pages=268-70 |year=1978 |pmid=636440}}</ref>


It leads to elevated [[liver function test]]s, which results from [[cholestasis|cholestatis]], i.e. a sessation of [[bile]] flow. The symptoms resolve if the renal cell cancer is sucessfully treated.<ref name=jakse/>
It leads to elevated [[liver function test]]s, which results from [[cholestasis|cholestatis]], i.e. a sessation of [[bile]] flow. The symptoms resolve if the renal cell cancer is sucessfully treated.<ref name=jakse/>

Revision as of 19:49, 15 June 2007

Stauffer[woo-hoo. that's my last name] syndrome is a constellation of signs and symptoms of liver dysfunction that arise due to presence of renal cell carcinoma[1] but are not due to tumour inflitration into the liver and/or intrinsic liver disease; it is a paraneoplastic syndrome.[2]

It leads to elevated liver function tests, which results from cholestatis, i.e. a sessation of bile flow. The symptoms resolve if the renal cell cancer is sucessfully treated.[2]

References

  1. ^ Stedman's Medical Dictionary. URL: http://www.emedicine.com/asp/dictionary.asp?keyword=Stauffer+syndrome. Accessed on: April 14, 2007.
  2. ^ a b Jakse G, Madersbacher H (1978). "[Stauffer's syndrome. Reversible hepatic dysfunction in renal cell carcinoma (author's transl)]". Wien Klin Wochenschr. 90 (8): 268–70. PMID 636440.