Nebulette: Difference between revisions
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'''Nebulette''' is an isoform of the protein [[nebulin]]. While nebulin (600-900 kDa) is expressed preferentially in [[skeletal muscle]], nebulette (107 kDa) is expressed in [[cardiac muscle]]. Nebulette was identified in 1995 by Mocman and Wang using primary cultures of chicken embryonic [[cardiomyocyte]]s by [[ |
'''Nebulette''' is an isoform of the protein [[nebulin]]. While nebulin (600-900 kDa) is expressed preferentially in [[skeletal muscle]], nebulette (107 kDa) is expressed in [[cardiac muscle]]. Nebulette was identified in 1995 by Mocman and Wang using primary cultures of chicken embryonic [[cardiomyocyte]]s by [[immunoprecipitation]]s with certain anti-nebulin [[monoclonal antibodies]].<ref name="moncman">{{cite journal |author=Moncman & Wang |title=Nebulette: a 107 kD nebulin-like protein in cardiac muscle |journal=Cell Motil Cytoskeleton |volume=32 |issue=3 |pages=205-25 |year=1995 |pmid=8581976 }}</ref> |
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==References== |
==References== |
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Revision as of 21:59, 14 July 2007
| nebulette | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | NEBL | ||||||
| NCBI gene | 10529 | ||||||
| HGNC | 16932 | ||||||
| OMIM | 605491 | ||||||
| RefSeq | NM_006393 | ||||||
| UniProt | O76041 | ||||||
| Other data | |||||||
| Locus | Chr. 10 p12 | ||||||
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Nebulette is an isoform of the protein nebulin. While nebulin (600-900 kDa) is expressed preferentially in skeletal muscle, nebulette (107 kDa) is expressed in cardiac muscle. Nebulette was identified in 1995 by Mocman and Wang using primary cultures of chicken embryonic cardiomyocytes by immunoprecipitations with certain anti-nebulin monoclonal antibodies.[1]
References
External links
- nebulette at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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