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==MCI Screen==
==MCI Screen==


The MCI Screen is a ten minute neuro-psychological test derived from the protocol of the CERAD 10-word recall test. The test consists of three immediate recall tasks, a triadic comparison task, a judgment task, a delayed free recall task, a cued-recall task, and a rehearsed recall task. It is scored using sophisticated mathematical methods and is 97.3% accurate for differentiating Normal cognitive function from Mild Cognitive Impairment<ref>Shankle WR, Romney AK, Hara J, et al. Method to improve the detection of mild cognitive impairment. PNAS. 2005; 102(13): 4919-24..
The MCI Screen is a ten minute neuro-psychological test derived from the protocol of the CERAD 10-word recall test. The test consists of three immediate recall tasks, a triadic comparison task, a judgment task, a delayed free recall task, a cued-recall task, and a rehearsed recall task. It is scored using sophisticated mathematical methods and is 97.3% accurate for differentiating Normal cognitive function from Mild Cognitive Impairment<ref>Shankle WR, Romney AK, Hara J, et al. Method to improve the detection of mild cognitive impairment. PNAS. 2005; 102(13): 4919-24.. </ref>




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==Clinical Validation==
==Clinical Validation==
The MCI Screen is used in clinical practice to identify early stage memory loss due to underlying medical conditions including Alzheimer's disease, cerebrovascular disease, and others<ref>Trenkle D, Shankle WR, Azen SP. Detecting Cognitive Impairment in Primary Care: Performance Assessment of Three Screening Instruments. Journal of Alzheimer's Disease. 2007; 11(3):323-335. [http://web1.mccare.com/pdf/JAD_Trenkle07_MCIS.pdf Detecting Cognitive Impairment in Primary Care].
The MCI Screen is used in clinical practice to identify early stage memory loss due to underlying medical conditions including Alzheimer's disease, cerebrovascular disease, and others<ref>Trenkle D, Shankle WR, Azen SP. Detecting Cognitive Impairment in Primary Care: Performance Assessment of Three Screening Instruments. Journal of Alzheimer's Disease. 2007; 11(3):323-335.</ref> [http://web1.mccare.com/pdf/JAD_Trenkle07_MCIS.pdf Detecting Cognitive Impairment in Primary Care].


==References==
==References==

Revision as of 23:15, 31 August 2007

MCI Screen

The MCI Screen is a ten minute neuro-psychological test derived from the protocol of the CERAD 10-word recall test. The test consists of three immediate recall tasks, a triadic comparison task, a judgment task, a delayed free recall task, a cued-recall task, and a rehearsed recall task. It is scored using sophisticated mathematical methods and is 97.3% accurate for differentiating Normal cognitive function from Mild Cognitive Impairment[1]


Technical Validation

The MCI Screen was validated in a study on 471 community dwelling adults whose scores on the Clinical Dementia Rating Scale ranged from 0 (normal: N=119), 0.5 (mild cognitive impairment: N=95), to 1 (mild dementia: N=257). The MCI Screen showed overall accuracy of 98% with sensitivity of 97% for mild cognitive impairment or mild dementia, and 88% specificity for normal aging. The accuracy of the MCI Screen has been published in the Proceedings of the National Academy of Sciences: Methods to Improve the Detection of Mild Cognitive Impairment.


Clinical Validation

The MCI Screen is used in clinical practice to identify early stage memory loss due to underlying medical conditions including Alzheimer's disease, cerebrovascular disease, and others[2] Detecting Cognitive Impairment in Primary Care.

References

  1. ^ Shankle WR, Romney AK, Hara J, et al. Method to improve the detection of mild cognitive impairment. PNAS. 2005; 102(13): 4919-24..
  2. ^ Trenkle D, Shankle WR, Azen SP. Detecting Cognitive Impairment in Primary Care: Performance Assessment of Three Screening Instruments. Journal of Alzheimer's Disease. 2007; 11(3):323-335.