K562 cells: Difference between revisions
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'''K562 cells''' are a specialized [[cell line]] of human [[erythroleukemia]] cells. Like [[HeLa]]cells, K562 cells are involved in various research experiments. |
'''K562 cells''' are a specialized [[cell line]] of human [[erythroleukemia]] cells. Like [[HeLa]]cells, K562 cells are involved in various research experiments. |
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K562 is a known chronic mylogenous [[leukemia]]. The cells are [[Philadelphia_chromosome]] positive, and normal K562s lack any [[MHC]]/HLA molecules. However, [[transfected]] lines are available that express MHC class-I A2 and A3 molecules, containing normally processed endogenous antigen. This transfection must be maintained by the addition of [[antibiotic]] G-418. |
K562 is a known chronic mylogenous [[leukemia]]. The cells are [[Philadelphia_chromosome]] positive, and normal K562s lack any [[MHC]]/HLA molecules. However, [[transfected]] lines are available that express MHC class-I A2 and A3 molecules, containing normally processed endogenous antigen. This [[transfection]] must be maintained by the addition of [[antibiotic]] G-418. |
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==External links== |
==External links== |
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Revision as of 14:50, 13 September 2007
K562 cells are a specialized cell line of human erythroleukemia cells. Like HeLacells, K562 cells are involved in various research experiments.
K562 is a known chronic mylogenous leukemia. The cells are Philadelphia_chromosome positive, and normal K562s lack any MHC/HLA molecules. However, transfected lines are available that express MHC class-I A2 and A3 molecules, containing normally processed endogenous antigen. This transfection must be maintained by the addition of antibiotic G-418.
External links
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