Talk:Oncogene: Difference between revisions
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== WikiProject class rating== |
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This article was automatically assessed because at least one WikiProject had rated the article as start, and the rating on other projects was brought up to start class. [[User:BetacommandBot|BetacommandBot]] 16:30, 10 November 2007 (UTC) |
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Style
I'm beginning to feel that the number of links and random facts are interrupting the continuity of this article (e.g. is it really necessary to attribute the institution of Varums and Bishop? probably not). However, I do feel that the discussion on mutations is quite helpful for understanding of the topic. Brandon Tavshanjian
microRNAs
I am interested in making some rather substantial changes to this page, but thought it might be best to float some ideas here first.
An example: the second (short) paragraph says:
"New research indicates that small RNAs 21-25 nucleotides in length called miRNAs can control expression of these genes by downregulating them."
This sentence is true, and there is a lot of interest to say about miRNAs and their involvement in cancer, but the above makes a generic statement about all genes that says nothing specific about oncogenes. On that basis, I would delete this paragraph.
Comments?
User:OncoAnalyst forgot to sign the above.
Delete or rewrite. I would start by rewriting the above as "microRNAs can control expression of these genes by downregulating them." and add relevant sources. Also please rewrite the section on the microRNA page about cancer. Una Smith 04:35, 14 June 2007 (UTC)
While I agree the connections between miRNAs and oncogenes are beginning to become intriguing, I really don't feel it belongs at the beginning of the article. I'm a big fan of the idea that these entries should be written in the "funnel" style, where we start with the most broad statements and then move on to specifics. In that light, miRNAs belong as a sub-heading later on in the article--placing them at the beginning is just confusing. It also doesn't necessarily contribute anything to the basic understanding of what an "oncogene" is.
WikiProject class rating
This article was automatically assessed because at least one WikiProject had rated the article as start, and the rating on other projects was brought up to start class. BetacommandBot 16:30, 10 November 2007 (UTC)