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Secobarbital: Difference between revisions

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'''Secobarbital''' is a [[Barbiturate]] and is available as either a free [[acid]] or a [[sodium]] [[salt]]. The free acid is a white [[amorphous]] powder that slightly soluble in water and very soluble in ethanol. The salt is a white [[hygroscopic]] powder that is soluble in water and ethanol. The main brand name is '''Seconal'''.
'''Secobarbital''' is a [[Barbiturate]] and is available as either a free [[acid]] or a [[sodium]] [[salt]]. The free acid is a white [[amorphous]] powder that slightly soluble in water and very soluble in ethanol. The salt is a white [[hygroscopic]] powder that is soluble in water and ethanol. The main brand name is '''Seconal'''.


As a prescription medication, it became a drug of abuse in the [[1960s]] and [[1970s]]. Seconal acquired the nickname "reds," by its users, as it was packaged in red capsules. Its main legitimate medical uses are for [[seizure]]s, tension relief (as before surgery), and as a temporary sleep aid. Secobarbital is fairly [[addiction|addictive]], and [[withdrawal]] symptoms can occur when a continual use is abruptly ended.


==Side Effects==
==Side Effects==
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* nightmares, nervousness, or anxiety;
* nightmares, nervousness, or anxiety;
* headaches
* headaches




[[category:barbiturates]]
[[category:barbiturates]]

Revision as of 17:32, 5 August 2005

Chemical structure of Secobarbital.
Chemical structure of Secobarbital.

Secobarbital

5-pentan-2-yl-5-prop-2-enyl-1,3-diazinane-2,4,6-trione

CAS number
76-73-3
ATC code
N05CA06
Empiric formula C12H18N2O3
Molecular weight 238.29 g/mole
Bioavailability ?
Metabolism Liver
Elimination half life ?
Excretion Urine
Pregnancy category D (USA)

Secobarbital sodium

sodium 5-(1-methylbutyl)-4,6-dioxo-5-prop-2-enyl-1H-pyrimidin-2-olate

CAS number
309-43-3
ATC code
N05CA06
Empiric formula C12H18N2NaO3
Molecular weight 260.265
Bioavailability ?
Metabolism Liver
Elimination half life ?
Excretion Urine
Pregnancy category D (USA)

Secobarbital is a Barbiturate and is available as either a free acid or a sodium salt. The free acid is a white amorphous powder that slightly soluble in water and very soluble in ethanol. The salt is a white hygroscopic powder that is soluble in water and ethanol. The main brand name is Seconal.

As a prescription medication, it became a drug of abuse in the 1960s and 1970s. Seconal acquired the nickname "reds," by its users, as it was packaged in red capsules. Its main legitimate medical uses are for seizures, tension relief (as before surgery), and as a temporary sleep aid. Secobarbital is fairly addictive, and withdrawal symptoms can occur when a continual use is abruptly ended.

Side Effects

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
  • a fever or a sore throat;
  • sores in your mouth;
  • broken blood vessels under your skin; or
  • easy bruising or bleeding;
  • drowsiness or dizziness;
  • confusion;
  • agitation, irritability, or excitability;
  • nightmares, nervousness, or anxiety;
  • headaches