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The pre-integration complex is generally comprised of the viral genetic material and associated proteins (viral and host) after release into the cell. In HIV, this includes the viral core which surrounds the RNA. This complex is responsible for reverse transcription of the viral RNA genome into dsDNA and prepares it for integration into the host DNA within the nucleus.
The pre-integration complex is generally comprised of the viral genetic material and associated proteins (viral and host) after release into the cell. In HIV, this includes the viral core which surrounds the RNA. This complex is responsible for reverse transcription of the viral RNA genome into dsDNA and prepares it for integration into the host DNA within the nucleus.


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Revision as of 22:07, 8 April 2008

The pre-integration complex is generally comprised of the viral genetic material and associated proteins (viral and host) after release into the cell. In HIV, this includes the viral core which surrounds the RNA. This complex is responsible for reverse transcription of the viral RNA genome into dsDNA and prepares it for integration into the host DNA within the nucleus.