EGLN2: Difference between revisions

EGLN2
Identifiers
Aliases	EGLN2, EIT6, HIF-PH1, HIFPH1, HPH-1, HPH-3, PHD1, egl-9 family hypoxia inducible factor 2, EIT-6
External IDs	OMIM: 606424; MGI: 1932287; HomoloGene: 14204; GeneCards: EGLN2; OMA:EGLN2 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	40,808,434 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	26,866,227 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; blood; ; spleen; ; right lung; ; apex of heart; ; upper lobe of left lung; ; mucosa of transverse colon; ; primary visual cortex; ; putamen;
	Top expressed in
	seminiferous tubule; ; entorhinal cortex; ; Ileal epithelium; ; perirhinal cortex; ; choroid plexus of fourth ventricle; ; CA3 field; ; spermatid; ; muscle of thigh; ; Paneth cell; ; crypt of lieberkuhn of small intestine;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	2-oxoglutarate-dependent dioxygenase activity; L-ascorbic acid binding; iron ion binding; dioxygenase activity; metal ion binding; protein binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; oxidoreductase activity; ferrous iron binding; oxygen gasoreceptor activity; peptidyl-proline 4-dioxygenase activity;
Cellular component	nucleoplasm; nucleus;
Biological process	response to hypoxia; positive regulation of protein catabolic process; regulation of neuron apoptotic process; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; cell redox homeostasis; regulation of cell growth; regulation of transcription from RNA polymerase II promoter in response to hypoxia; intracellular estrogen receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	112398
	112406
	ENSG00000269858
	ENSMUSG00000058709
	Q96KS0
	Q91YE2
	NM_080732; NM_017555; NM_053046
	NM_053208; NM_001357767
	NP_444274; NP_542770
	NP_444438; NP_001344696
	Wikidata
View/Edit Human	View/Edit Mouse

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Revision as of 18:57, 5 May 2008

Template:PBB Controls

Egl nine homolog 2 (C. elegans), also known as EGLN2, is a human gene.^[5]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000269858 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000058709 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: EGLN2 egl nine homolog 2 (C. elegans)".

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Revision as of 18:57, 5 May 2008

References

Further reading