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'''Janeway lesions''' are non-[[tender]], small [[erythema]]tous or [[hemorrhage|haemorrhagic]] [[macule]]s or [[nodule]]s in the palms or soles, which are [[pathognomonic]] of [[endocarditis|infective endocarditis]]. The pathology is due to a type III [[hypersensitivity]] reaction.
'''Janeway lesions''' are non-[[tender]], small [[erythema]]tous or [[hemorrhage|haemorrhagic]] [[macule]]s or [[nodule]]s in the palms or soles, which are [[pathognomonic]] of [[endocarditis|infective endocarditis]]. The pathology is due to septic emboli.


They are named after [[Edward G. Janeway]] (1872&ndash;1917), a [[professor]] of [[medicine]] with interests in [[cardiology]] and [[infectious disease]].<ref>{{cite journal |author=Janeway C |title=Presidential Address to The American Association of Immunologists. The road less traveled by: the role of innate immunity in the adaptive immune response |journal=J. Immunol. |volume=161 |issue=2 |pages=539-44 |year=1998 |pmid=9670925}}</ref>
They are named after [[Edward G. Janeway]] (1872&ndash;1917), a [[professor]] of [[medicine]] with interests in [[cardiology]] and [[infectious disease]].<ref>{{cite journal |author=Janeway C |title=Presidential Address to The American Association of Immunologists. The road less traveled by: the role of innate immunity in the adaptive immune response |journal=J. Immunol. |volume=161 |issue=2 |pages=539-44 |year=1998 |pmid=9670925}}</ref>

Revision as of 20:07, 19 May 2008

Janeway lesions are non-tender, small erythematous or haemorrhagic macules or nodules in the palms or soles, which are pathognomonic of infective endocarditis. The pathology is due to septic emboli.

They are named after Edward G. Janeway (1872–1917), a professor of medicine with interests in cardiology and infectious disease.[1]

See also

References

  1. ^ Janeway C (1998). "Presidential Address to The American Association of Immunologists. The road less traveled by: the role of innate immunity in the adaptive immune response". J. Immunol. 161 (2): 539–44. PMID 9670925.