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{{Rfam_box|acc=RF00486|description=mir-129 microRNA precursor family|abbreviation=mir-129|type=Gene; miRNA;|avg_length=91.1|avg_identity=82|ss=Predicted; PFOLD;|se=Moxon SJ|type=Gene; miRNA;}}
{{Rfam_box|acc=RF00486|description=mir-129 microRNA precursor family|abbreviation=mir-129|type=Gene; miRNA;|avg_length=91.1|avg_identity=82|ss=Predicted; PFOLD;|se=Moxon SJ|type=Gene; miRNA;}}


The '''miR-129 microRNA precursor''' is a small [[non-coding RNA]] molecule that regulates [[gene expression]]. This [[microRNA]] was first experimentally characterised in mouse<ref>{{cite journal | last = Lagos-Quintana | first = M | coauthors = Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T | year = 2002 | title = Identification of tissue-specific microRNAs from mouse | journal = Curr Biol | volume = 12 | pages = 735&ndash;739 | id = PMID 12007417}}</ref> and homologues have since been discovered in several other species. The mature sequence is excised by the [[Dicer]] enzyme from the 5' arm of the [[stem-loop|hairpin]].
The '''miR-129 microRNA precursor''' is a small [[non-coding RNA]] molecule that regulates [[gene expression]]. This [[microRNA]] was first experimentally characterised in mouse<ref>{{cite journal | last = Lagos-Quintana | first = M | coauthors = Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T | year = 2002 | title = Identification of tissue-specific microRNAs from mouse | journal = Curr Biol | volume = 12 | pages = 735&ndash;739 | pmid = 12007417 | doi = 10.1016/S0960-9822(02)00809-6}}</ref> and homologues have since been discovered in several other species. The mature sequence is excised by the [[Dicer]] enzyme from the 5' arm of the [[stem-loop|hairpin]].


==References==
==References==
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{{reflist|1}}
{{reflist|1}}


* [2] {{cite journal | last = Lagos-Quintana | first = M | coauthors = Rauhut R, Meyer J, Borkhardt A, Tuschl T | year = 2003 | title = New microRNAs from mouse and human | journal = RNA | volume = 9 | pages = 175&ndash;179 | id = PMID 12554859}}
* [2] {{cite journal | last = Lagos-Quintana | first = M | coauthors = Rauhut R, Meyer J, Borkhardt A, Tuschl T | year = 2003 | title = New microRNAs from mouse and human | journal = RNA | volume = 9 | pages = 175&ndash;179 | pmid = 12554859 | doi = 10.1261/rna.2146903}}


==External links==
==External links==

Revision as of 13:36, 8 June 2008

Mir-129 microRNA precursor family
Identifiers
Other data
PDB structuresPDBe

The miR-129 microRNA precursor is a small non-coding RNA molecule that regulates gene expression. This microRNA was first experimentally characterised in mouse[1] and homologues have since been discovered in several other species. The mature sequence is excised by the Dicer enzyme from the 5' arm of the hairpin.

References

  1. ^ Lagos-Quintana, M (2002). "Identification of tissue-specific microRNAs from mouse". Curr Biol. 12: 735–739. doi:10.1016/S0960-9822(02)00809-6. PMID 12007417. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)