Tre recombinase: Difference between revisions
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==External links== |
==External links== |
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* [http://www.sciam.com/article.cfm?articleID=737AB56E-E7F2-99DF-382B756D1860EACA&chanID=sa003 Designer Enzyme Cuts HIV Out of Infected Cells] |
* [http://www.sciam.com/article.cfm?articleID=737AB56E-E7F2-99DF-382B756D1860EACA&chanID=sa003 Designer Enzyme Cuts HIV Out of Infected Cells] |
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* [http://www.physorg.com/news102261327.html Potential cure for HIV discovered] |
* [http://www.physorg.com/news102261327.html Potential cure for HIV discovered]{{deadlink}} |
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* [http://www.sciencemag.org/cgi/content/abstract/316/5833/1912 HIV-1 Proviral DNA Excision Using an Evolved Recombinase] |
* [http://www.sciencemag.org/cgi/content/abstract/316/5833/1912 HIV-1 Proviral DNA Excision Using an Evolved Recombinase] |
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Revision as of 05:41, 9 June 2008
Tre recombinase is an experimental enzyme that in lab tests has successfully removed DNA inserted by HIV from infected cells[1]. The enzyme was derived from Cre recombinase through selective mutation for the purposes of identifying HIV markers, which are not bounded by loxP sites and therefore disallow attempts at Cre-Lox recombination.
References
- ^ Sarkar, I. et al. (2007): HIV-1 proviral DNA excision using an evolved recombinase. In: Science. Bd. 316, S. 1912-1915. PMID 17600219 doi:10.1126/science.1141453
External links
- Designer Enzyme Cuts HIV Out of Infected Cells
- Potential cure for HIV discovered[dead link]
- HIV-1 Proviral DNA Excision Using an Evolved Recombinase
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