GPR98: Difference between revisions

ADGRV1
Identifiers
Aliases	ADGRV1, FEB4, MASS1, USH2B, USH2C, VLGR1, VLGR1b, GPR98, adhesion G protein-coupled receptor V1
External IDs	OMIM: 602851; MGI: 1274784; HomoloGene: 19815; GeneCards: ADGRV1; OMA:ADGRV1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	91,164,437 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	81,781,273 bp
RNA expression pattern
	Top expressed in
	right adrenal cortex; ; left adrenal gland; ; ventricular zone; ; left adrenal cortex; ; ganglionic eminence; ; caudate nucleus; ; nucleus accumbens; ; putamen; ; Amygdala; ; anterior pituitary;
	Top expressed in
	neural layer of retina; ; ventricular zone; ; lens; ; spermatid; ; barrel cortex; ; cumulus cell; ; spermatocyte; ; optic nerve; ; embryo; ; saccule;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; G protein-coupled receptor activity; signal transducer activity; protein binding; transmembrane signaling receptor activity; G-protein alpha-subunit binding; adenylate cyclase inhibitor activity; hydrolase activity;
Cellular component	cytoplasm; integral component of membrane; membrane; receptor complex; plasma membrane; synapse; stereocilium; cell surface; extracellular exosome; photoreceptor inner segment; stereocilia ankle link; stereocilia ankle link complex; cell projection; stereocilium membrane; periciliary membrane compartment; USH2 complex;
Biological process	G protein-coupled receptor signaling pathway; response to stimulus; nervous system process; sensory perception of light stimulus; hearing; nervous system development; cell communication; cell surface receptor signaling pathway; photoreceptor cell maintenance; maintenance of animal organ identity; signal transduction; visual perception; cell-cell adhesion; negative regulation of adenylate cyclase activity; positive regulation of protein kinase A signaling; positive regulation of bone mineralization; regulation of protein stability; establishment of protein localization; inner ear development; detection of mechanical stimulus involved in sensory perception of sound; inner ear receptor cell stereocilium organization; cellular response to calcium ion; positive regulation of protein kinase C signaling; self proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	84059
	110789
	ENSG00000164199
	ENSMUSG00000069170
	Q8WXG9
	Q8VHN7
	NM_032119
	NM_054053
	NP_115495
	NP_473394
	Wikidata
View/Edit Human	View/Edit Mouse

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Revision as of 23:21, 9 June 2008

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G protein-coupled receptor 98, also known as GPR98, is a human protein and gene.^[5]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000164199 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000069170 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: GPR98 G protein-coupled receptor 98".

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 | citations =
-*{{cite journal  | author=Nakajima D, Okazaki N, Yamakawa H, ''et al.'' |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99-106 |year= 2003 |pmid= 12168954 |doi=  }}
+*{{cite journal  | author=Nakajima D, Okazaki N, Yamakawa H, ''et al.'' |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99–106 |year= 2003 |pmid= 12168954 |doi=  }}
-*{{cite journal  | author=Staub E, Pérez-Tur J, Siebert R, ''et al.'' |title=The novel EPTP repeat defines a superfamily of proteins implicated in epileptic disorders. |journal=Trends Biochem. Sci. |volume=27 |issue= 9 |pages= 441-4 |year= 2002 |pmid= 12217514 |doi=  }}
+*{{cite journal  | author=Staub E, Pérez-Tur J, Siebert R, ''et al.'' |title=The novel EPTP repeat defines a superfamily of proteins implicated in epileptic disorders. |journal=Trends Biochem. Sci. |volume=27 |issue= 9 |pages= 441–4 |year= 2002 |pmid= 12217514 |doi=  }}
-*{{cite journal  | author=Ishikawa K, Nagase T, Suyama M, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 3 |pages= 169-76 |year= 1998 |pmid= 9734811 |doi=  }}
+*{{cite journal  | author=Ishikawa K, Nagase T, Suyama M, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 3 |pages= 169–76 |year= 1998 |pmid= 9734811 |doi=  }}
-*{{cite journal  | author=Nakayama J, Hamano K, Iwasaki N, ''et al.'' |title=Significant evidence for linkage of febrile seizures to chromosome 5q14-q15. |journal=Hum. Mol. Genet. |volume=9 |issue= 1 |pages= 87-91 |year= 2000 |pmid= 10587582 |doi=  }}
+*{{cite journal  | author=Nakayama J, Hamano K, Iwasaki N, ''et al.'' |title=Significant evidence for linkage of febrile seizures to chromosome 5q14-q15. |journal=Hum. Mol. Genet. |volume=9 |issue= 1 |pages= 87–91 |year= 2000 |pmid= 10587582 |doi=  }}
-*{{cite journal  | author=Pieke-Dahl S, Möller CG, Kelley PM, ''et al.'' |title=Genetic heterogeneity of Usher syndrome type II: localisation to chromosome 5q. |journal=J. Med. Genet. |volume=37 |issue= 4 |pages= 256-62 |year= 2000 |pmid= 10745043 |doi=  }}
+*{{cite journal  | author=Pieke-Dahl S, Möller CG, Kelley PM, ''et al.'' |title=Genetic heterogeneity of Usher syndrome type II: localisation to chromosome 5q. |journal=J. Med. Genet. |volume=37 |issue= 4 |pages= 256–62 |year= 2000 |pmid= 10745043 |doi=  }}
-*{{cite journal  | author=Nikkila H, McMillan DR, Nunez BS, ''et al.'' |title=Sequence similarities between a novel putative G protein-coupled receptor and Na+/Ca2+ exchangers define a cation binding domain. |journal=Mol. Endocrinol. |volume=14 |issue= 9 |pages= 1351-64 |year= 2001 |pmid= 10976914 |doi=  }}
+*{{cite journal  | author=Nikkila H, McMillan DR, Nunez BS, ''et al.'' |title=Sequence similarities between a novel putative G protein-coupled receptor and Na+/Ca2+ exchangers define a cation binding domain. |journal=Mol. Endocrinol. |volume=14 |issue= 9 |pages= 1351–64 |year= 2001 |pmid= 10976914 |doi=  }}
-*{{cite journal  | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
+*{{cite journal  | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
-*{{cite journal  | author=Skradski SL, Clark AM, Jiang H, ''et al.'' |title=A novel gene causing a mendelian audiogenic mouse epilepsy. |journal=Neuron |volume=31 |issue= 4 |pages= 537-44 |year= 2001 |pmid= 11545713 |doi=  }}
+*{{cite journal  | author=Skradski SL, Clark AM, Jiang H, ''et al.'' |title=A novel gene causing a mendelian audiogenic mouse epilepsy. |journal=Neuron |volume=31 |issue= 4 |pages= 537–44 |year= 2001 |pmid= 11545713 |doi=  }}
-*{{cite journal  | author=McMillan DR, Kayes-Wandover KM, Richardson JA, White PC |title=Very large G protein-coupled receptor-1, the largest known cell surface protein, is highly expressed in the developing central nervous system. |journal=J. Biol. Chem. |volume=277 |issue= 1 |pages= 785-92 |year= 2002 |pmid= 11606593 |doi= 10.1074/jbc.M108929200 }}
+*{{cite journal  | author=McMillan DR, Kayes-Wandover KM, Richardson JA, White PC |title=Very large G protein-coupled receptor-1, the largest known cell surface protein, is highly expressed in the developing central nervous system. |journal=J. Biol. Chem. |volume=277 |issue= 1 |pages= 785–92 |year= 2002 |pmid= 11606593 |doi= 10.1074/jbc.M108929200 }}
-*{{cite journal  | author=Nagase T, Kikuno R, Ohara O |title=Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. |journal=DNA Res. |volume=8 |issue= 6 |pages= 319-27 |year= 2002 |pmid= 11853319 |doi=  }}
+*{{cite journal  | author=Nagase T, Kikuno R, Ohara O |title=Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. |journal=DNA Res. |volume=8 |issue= 6 |pages= 319–27 |year= 2002 |pmid= 11853319 |doi=  }}
-*{{cite journal  | author=Nakayama J, Fu YH, Clark AM, ''et al.'' |title=A nonsense mutation of the MASS1 gene in a family with febrile and afebrile seizures. |journal=Ann. Neurol. |volume=52 |issue= 5 |pages= 654-7 |year= 2002 |pmid= 12402266 |doi= 10.1002/ana.10347 }}
+*{{cite journal  | author=Nakayama J, Fu YH, Clark AM, ''et al.'' |title=A nonsense mutation of the MASS1 gene in a family with febrile and afebrile seizures. |journal=Ann. Neurol. |volume=52 |issue= 5 |pages= 654–7 |year= 2002 |pmid= 12402266 |doi= 10.1002/ana.10347 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
-*{{cite journal  | author=Weston MD, Luijendijk MW, Humphrey KD, ''et al.'' |title=Mutations in the VLGR1 gene implicate G-protein signaling in the pathogenesis of Usher syndrome type II. |journal=Am. J. Hum. Genet. |volume=74 |issue= 2 |pages= 357-66 |year= 2004 |pmid= 14740321 |doi=  }}
+*{{cite journal  | author=Weston MD, Luijendijk MW, Humphrey KD, ''et al.'' |title=Mutations in the VLGR1 gene implicate G-protein signaling in the pathogenesis of Usher syndrome type II. |journal=Am. J. Hum. Genet. |volume=74 |issue= 2 |pages= 357–66 |year= 2004 |pmid= 14740321 |doi=  }}
-*{{cite journal  | author=Bjarnadóttir TK, Fredriksson R, Höglund PJ, ''et al.'' |title=The human and mouse repertoire of the adhesion family of G-protein-coupled receptors. |journal=Genomics |volume=84 |issue= 1 |pages= 23-33 |year= 2005 |pmid= 15203201 |doi= 10.1016/j.ygeno.2003.12.004 }}
+*{{cite journal  | author=Bjarnadóttir TK, Fredriksson R, Höglund PJ, ''et al.'' |title=The human and mouse repertoire of the adhesion family of G-protein-coupled receptors. |journal=Genomics |volume=84 |issue= 1 |pages= 23–33 |year= 2005 |pmid= 15203201 |doi= 10.1016/j.ygeno.2003.12.004 }}
-*{{cite journal  | author=Fu GK, Wang JT, Yang J, ''et al.'' |title=Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. |journal=Genomics |volume=84 |issue= 1 |pages= 205-10 |year= 2005 |pmid= 15203218 |doi= 10.1016/j.ygeno.2004.01.011 }}
+*{{cite journal  | author=Fu GK, Wang JT, Yang J, ''et al.'' |title=Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. |journal=Genomics |volume=84 |issue= 1 |pages= 205–10 |year= 2005 |pmid= 15203218 |doi= 10.1016/j.ygeno.2004.01.011 }}
-*{{cite journal  | author=Schwartz SB, Aleman TS, Cideciyan AV, ''et al.'' |title=Disease expression in Usher syndrome caused by VLGR1 gene mutation (USH2C) and comparison with USH2A phenotype. |journal=Invest. Ophthalmol. Vis. Sci. |volume=46 |issue= 2 |pages= 734-43 |year= 2005 |pmid= 15671307 |doi= 10.1167/iovs.04-1136 }}
+*{{cite journal  | author=Schwartz SB, Aleman TS, Cideciyan AV, ''et al.'' |title=Disease expression in Usher syndrome caused by VLGR1 gene mutation (USH2C) and comparison with USH2A phenotype. |journal=Invest. Ophthalmol. Vis. Sci. |volume=46 |issue= 2 |pages= 734–43 |year= 2005 |pmid= 15671307 |doi= 10.1167/iovs.04-1136 }}
-*{{cite journal  | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
+*{{cite journal  | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
 }}
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Revision as of 23:21, 9 June 2008

References

Further reading