PBX1: Difference between revisions
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{{PBB|geneid=5087}} |
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. --> |
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{{GNF_Protein_box |
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| image = PBB_Protein_PBX1_image.jpg |
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| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1b72. |
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| PDB = {{PDB2|1b72}}, {{PDB2|1b8i}}, {{PDB2|1du6}}, {{PDB2|1lfu}}, {{PDB2|1puf}} |
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| Name = Pre-B-cell leukemia homeobox 1 |
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| HGNCid = 8632 |
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| Symbol = PBX1 |
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| AltSymbols =; DKFZp686B09108; MGC126627 |
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| OMIM = 176310 |
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| ECnumber = |
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| Homologene = 20574 |
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| MGIid = 97495 |
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| GeneAtlas_image1 = PBB_GE_PBX1_205253_at_tn.png |
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| Function = {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0043565 |text = sequence-specific DNA binding}} {{GNF_GO|id=GO:0046982 |text = protein heterodimerization activity}} |
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| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} |
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| Process = {{GNF_GO|id=GO:0001655 |text = urogenital system development}} {{GNF_GO|id=GO:0001658 |text = ureteric bud branching}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0006366 |text = transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0006700 |text = C21-steroid hormone biosynthetic process}} {{GNF_GO|id=GO:0007548 |text = sex differentiation}} {{GNF_GO|id=GO:0008284 |text = positive regulation of cell proliferation}} {{GNF_GO|id=GO:0009790 |text = embryonic development}} {{GNF_GO|id=GO:0009887 |text = organ morphogenesis}} {{GNF_GO|id=GO:0030154 |text = cell differentiation}} {{GNF_GO|id=GO:0030325 |text = adrenal gland development}} {{GNF_GO|id=GO:0030902 |text = hindbrain development}} {{GNF_GO|id=GO:0045898 |text = regulation of transcriptional preinitiation complex assembly}} {{GNF_GO|id=GO:0045944 |text = positive regulation of transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0048536 |text = spleen development}} |
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| Orthologs = {{GNF_Ortholog_box |
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| Hs_EntrezGene = 5087 |
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| Hs_Ensembl = ENSG00000185630 |
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| Hs_RefseqProtein = NP_002576 |
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| Hs_RefseqmRNA = NM_002585 |
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| Hs_GenLoc_db = |
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| Hs_GenLoc_chr = 1 |
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| Hs_GenLoc_start = 162795496 |
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| Hs_GenLoc_end = 163087691 |
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| Hs_Uniprot = P40424 |
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| Mm_EntrezGene = 18514 |
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| Mm_Ensembl = |
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| Mm_RefseqmRNA = NM_008783 |
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| Mm_RefseqProtein = NP_032809 |
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| Mm_GenLoc_db = |
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| Mm_GenLoc_chr = |
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| Mm_GenLoc_start = |
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| Mm_GenLoc_end = |
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| Mm_Uniprot = |
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}} |
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}} |
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'''Pre-B-cell leukemia homeobox 1''', also known as '''PBX1''', is a human [[gene]].<ref>{{cite web | title = Entrez Gene: PBX1 Pre-B-cell leukemia homeobox 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5087| accessdate = }}</ref> |
'''Pre-B-cell leukemia homeobox 1''', also known as '''PBX1''', is a human [[gene]].<ref>{{cite web | title = Entrez Gene: PBX1 Pre-B-cell leukemia homeobox 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5087| accessdate = }}</ref> |
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[[fr:Pbx1]] |
[[fr:Pbx1]] |
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Revision as of 09:05, 8 July 2008
Template:PBB Pre-B-cell leukemia homeobox 1, also known as PBX1, is a human gene.[1]
References
Further reading
- Sanyal M, Tung JW (2007). "B-cell development fails in the absence of the Pbx1 proto-oncogene". Blood. 109 (10): 4191–9. doi:10.1182/blood-2006-10-054213. PMID 17244677.
 | This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it. |