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{{PBB|geneid=9138}}
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{{GNF_Protein_box
| image = PBB_Protein_ARHGEF1_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1iap.
| PDB = {{PDB2|1iap}}, {{PDB2|1shz}}
| Name = Rho guanine nucleotide exchange factor (GEF) 1
| HGNCid = 681
| Symbol = ARHGEF1
| AltSymbols =; GEF1; LBCL2; P115-RHOGEF; SUB1.5
| OMIM = 601855
| ECnumber =
| Homologene = 3454
| MGIid = 1353510
| GeneAtlas_image1 = PBB_GE_ARHGEF1_203055_s_at_tn.png
| Function = {{GNF_GO|id=GO:0005085 |text = guanyl-nucleotide exchange factor activity}} {{GNF_GO|id=GO:0005089 |text = Rho guanyl-nucleotide exchange factor activity}} {{GNF_GO|id=GO:0005096 |text = GTPase activator activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005622 |text = intracellular}} {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005886 |text = plasma membrane}}
| Process = {{GNF_GO|id=GO:0000074 |text = regulation of progression through cell cycle}} {{GNF_GO|id=GO:0008283 |text = cell proliferation}} {{GNF_GO|id=GO:0035023 |text = regulation of Rho protein signal transduction}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 9138
| Hs_Ensembl = ENSG00000076928
| Hs_RefseqProtein = NP_004697
| Hs_RefseqmRNA = NM_004706
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 19
| Hs_GenLoc_start = 47079090
| Hs_GenLoc_end = 47103437
| Hs_Uniprot = Q92888
| Mm_EntrezGene = 16801
| Mm_Ensembl = ENSMUSG00000040940
| Mm_RefseqmRNA = NM_008488
| Mm_RefseqProtein = NP_032514
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 7
| Mm_GenLoc_start = 24616494
| Mm_GenLoc_end = 24634891
| Mm_Uniprot = Q6KAM6
}}
}}
'''Rho guanine nucleotide exchange factor (GEF) 1''', also known as '''ARHGEF1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9138| accessdate = }}</ref>
'''Rho guanine nucleotide exchange factor (GEF) 1''', also known as '''ARHGEF1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9138| accessdate = }}</ref>


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{{gene-19-stub}}

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Revision as of 14:22, 9 July 2008

Template:PBB Rho guanine nucleotide exchange factor (GEF) 1, also known as ARHGEF1, is a human gene.[1]

Template:PBB Summary

References

  1. ^ "Entrez Gene: ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1".

Further reading

Template:PBB Controls