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{{Drugbox
{{Drugbox
| IUPAC_name = N1-(4-methoxybenzyl)- N2,N2-dimethyl- N1-(pyridin-2-yl)ethane- 1,2-diamine
| IUPAC_name = ''N''-[2-(dimethylamino)ethyl]-''N''-[(4-methoxyphenyl)methyl]pyridin-2-amine
| image = Mepyramine.svg
| image = Mepyramine.svg
| CAS_number = 91-84-9
| CAS_number = 91-84-9

Revision as of 11:55, 21 December 2008

Mepyramine
Clinical data
ATC code
Identifiers
  • N-[2-(dimethylamino)ethyl]-N-[(4-methoxyphenyl)methyl]pyridin-2-amine
CAS Number
CompTox Dashboard (EPA)
ECHA InfoCard100.001.912 Edit this at Wikidata
Chemical and physical data
FormulaC17H23N3O
Molar mass285.38 g/mol g·mol−1

Mepyramine (INN, also known as pyrilamine) [1] is a first generation antihistamine, targeting the H1 receptor. However, it rapidly permeates the brain and so often causes drowsiness as a side effect.

It is used in over-the-counter combination products for colds and menstrual symptoms.[2]

Side effects may include sedation/drowsiness, muscle weakness, and insomnia.[3]

References

  1. ^ Parsons, M. E. and Ganellin, C. R. (2006). "Histamine and its receptors". British Journal of Pharmacology. 147: S127–S135. doi:10.1038/sj.bjp.0706440. PMID 16402096.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. ^ Dysmenorrhea: How to Relieve Cramps
  3. ^ Pyrilamine Maleate patient advice including side effects