Chromosome 17: Difference between revisions
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* [[Usher syndrome type I]] |
* [[Usher syndrome type I]] |
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* [[very long-chain acyl-coenzyme A dehydrogenase deficiency]] |
* [[very long-chain acyl-coenzyme A dehydrogenase deficiency]] |
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==References== |
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* {{Journal reference issue | Author=Gilbert F | Title=Disease genes and chromosomes: disease maps of the human genome. Chromosome 17 | Journal=Genet Test | Year=1998 | Pages=357-81 | Volume=2 | Issue=4 }} PMID 10464617 |
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Revision as of 13:44, 17 December 2005
Chromosome 17 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 17 spans more than 81 million base pairs (the building material of DNA) and represents between 2.5 and 3 percent of the total DNA in cells.
Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 17 likely contains between 1,200 and 1,500 genes.
Genes
The following are some of the genes located on chromosome 17:
- ACADVL: acyl-coenzyme A dehydrogenase, very long chain
- ACTG1: actin, gamma 1
- ASPA: aspartoacylase (Canavan disease)
- BRCA1: breast cancer 1, early onset
- COL1A1: collagen, type I, alpha 1
- ERBB2: v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
- FLCN: folliculin
- GALK1: galactokinase 1
- GFAP: glial fibrillary acidic protein
- KCNJ2: potassium inwardly-rectifying channel, subfamily J, member 2
- MYO15A: myosin XVA
- NF1: neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)
- PMP22: peripheral myelin protein 22
- TP53: tumor protein p53 (Li-Fraumeni syndrome)
- USH1G: Usher syndrome 1G (autosomal recessive)
Diseases
The following diseases are some of those related to genes on chromosome 17:
- Alexander disease
- Andersen-Tawil syndrome
- Birt-Hogg-Dubé syndrome
- bladder cancer
- breast cancer
- Canavan disease
- Charcot-Marie-Tooth disease
- Charcot-Marie-Tooth disease, type 1
- Ehlers-Danlos syndrome
- Ehlers-Danlos syndrome, arthrochalasia type
- Ehlers-Danlos syndrome, classical type
- galactosemia
- hereditary neuropathy with liability to pressure palsies
- Li-Fraumeni syndrome
- neurofibromatosis type 1
- nonsyndromic deafness
- nonsyndromic deafness, autosomal dominant
- nonsyndromic deafness, autosomal recessive
- osteogenesis imperfecta
- osteogenesis imperfecta, type I
- osteogenesis imperfecta, type II
- osteogenesis imperfecta, type III
- osteogenesis imperfecta, type IV
- Usher syndrome
- Usher syndrome type I
- very long-chain acyl-coenzyme A dehydrogenase deficiency
References
- Template:Journal reference issue PMID 10464617
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