Cefprozil: Difference between revisions
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Script assisted update of chemical identifiers from ChemSpider for the Chem/Drugbox validation project. |
Updating {{drugbox}} (no changed fields - added verified revid - updated 'CASNo_Ref') per Chem/Drugbox validation (report errors or [[user talk:CheMoBo |
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{{drugbox |
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| verifiedrevid = 327652774 |
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| IUPAC_name = 8-[2-amino-2-(4-hydroxyphenyl)-acetyl] amino-7-oxo-4-prop-1-enyl-2-thia-6- azabicyclo [ 4.2.0]oct-4-ene-5-carboxylic acid |
| IUPAC_name = 8-[2-amino-2-(4-hydroxyphenyl)-acetyl] amino-7-oxo-4-prop-1-enyl-2-thia-6- azabicyclo [ 4.2.0]oct-4-ene-5-carboxylic acid |
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| image = Cefprozil.svg |
| image = Cefprozil.svg |
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| smiles = O=C2N1/C(=C(/C=C/C)CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccc(O)cc3)N)C(=O)O.O |
| smiles = O=C2N1/C(=C(/C=C/C)CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccc(O)cc3)N)C(=O)O.O |
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| InChIKey = ALYUMNAHLSSTOU-CIRGZYLNBD |
| InChIKey = ALYUMNAHLSSTOU-CIRGZYLNBD |
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| CASNo_Ref = {{cascite}} |
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| CAS_number = 92665-29-7 |
| CAS_number = 92665-29-7 |
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| ATC_prefix = J01 |
| ATC_prefix = J01 |
Revision as of 12:22, 24 November 2009
Clinical data | |
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Pregnancy category |
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Routes of administration | ORAL |
ATC code | |
Pharmacokinetic data | |
Bioavailability | 95% |
Protein binding | 36% |
Elimination half-life | 1.3 hours |
Identifiers | |
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CAS Number | |
PubChem CID | |
DrugBank | |
ChemSpider | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C18H19N3O5S |
Molar mass | 389.427 g/mol g·mol−1 |
3D model (JSmol) | |
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(verify) |
Cefprozil, sometimes spelled cefproxil and sold under the brand name Cefzil, is a cephalosporin type antibiotic. In Europe, it is sold by the name Procef. It can be used to treat bronchitis, ear infections, skin infections, and other bacterial infections. It comes as a tablet and as a liquid suspension.
Although there is a widely quoted cross-allergy risk of 10% between cephalosporins and penicillin, an article in the Journal of Family Practice (February 2006)[1] has shown no increased risk for cross-allergy for cefprozil and several other 2nd generation or later cephalosporins.