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Cefprozil: Difference between revisions

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{{drugbox
{{drugbox
| verifiedrevid = 327652774
| IUPAC_name = 8-[2-amino-2-(4-hydroxyphenyl)-acetyl] amino-7-oxo-4-prop-1-enyl-2-thia-6- azabicyclo [ 4.2.0]oct-4-ene-5-carboxylic acid
| IUPAC_name = 8-[2-amino-2-(4-hydroxyphenyl)-acetyl] amino-7-oxo-4-prop-1-enyl-2-thia-6- azabicyclo [ 4.2.0]oct-4-ene-5-carboxylic acid
| image = Cefprozil.svg
| image = Cefprozil.svg
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| smiles = O=C2N1/C(=C(/C=C/C)CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccc(O)cc3)N)C(=O)O.O
| smiles = O=C2N1/C(=C(/C=C/C)CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccc(O)cc3)N)C(=O)O.O
| InChIKey = ALYUMNAHLSSTOU-CIRGZYLNBD
| InChIKey = ALYUMNAHLSSTOU-CIRGZYLNBD
| CASNo_Ref = {{cascite}}
| CAS_number = 92665-29-7
| CAS_number = 92665-29-7
| ATC_prefix = J01
| ATC_prefix = J01

Revision as of 12:22, 24 November 2009

Cefprozil
Clinical data
Pregnancy
category
  • Category-B
Routes of
administration
ORAL
ATC code
Pharmacokinetic data
Bioavailability95%
Protein binding36%
Elimination half-life1.3 hours
Identifiers
  • 8-[2-amino-2-(4-hydroxyphenyl)-acetyl] amino-7-oxo-4-prop-1-enyl-2-thia-6- azabicyclo [ 4.2.0]oct-4-ene-5-carboxylic acid
CAS Number
PubChem CID
DrugBank
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H19N3O5S
Molar mass389.427 g/mol g·mol−1
3D model (JSmol)
  • O=C2N1/C(=C(/C=C/C)CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccc(O)cc3)N)C(=O)O.O
  (verify)

Cefprozil, sometimes spelled cefproxil and sold under the brand name Cefzil, is a cephalosporin type antibiotic. In Europe, it is sold by the name Procef. It can be used to treat bronchitis, ear infections, skin infections, and other bacterial infections. It comes as a tablet and as a liquid suspension.

Although there is a widely quoted cross-allergy risk of 10% between cephalosporins and penicillin, an article in the Journal of Family Practice (February 2006)[1] has shown no increased risk for cross-allergy for cefprozil and several other 2nd generation or later cephalosporins.

References