Jump to content

Firestone Institute for Respiratory Health: Difference between revisions

Add links
From Wikipedia, the free encyclopedia
Browse history interactively
← Previous editNext edit →
Content deleted Content added
VisualWikitext
m Chronic obstructive pulmonary disease
m →History: fixing page range dashes using Project:AWB
Line 19: Line 19:
==History==
==History==


Founded in 1978 as the Firestone Regional Chest and Allergy Unit(FRCAU), the institute was designated as the Regional Referral Center by the District Health Council. The institute has maintained this designation, and as of 2006, it services the Hamilton Niagara Haldimand Brant Local Health Integration Network, a community of 1.4 million people. <ref name=firhhist>{{citation|title= Firestone Institute for Respiratory Health: History |url= http://www.firh.ca/Documents/firh_history.htm |accessdate= 2009-02-07 }}</ref> The institute's research developed in collaboration with clinical activities in order to comprehensively investigate mechanisms and outcomes. Accordingly, a number of [[asthma]] and [[Chronic obstructive pulmonary disease|COPD]] initiatives were launched, including the development of standardized techniques for symptom assessment, airflow limitation and [[bronchial hyperresponsiveness]]. Further investigations have included studies of exercise and allergen-induced bronchoconstriction as well as epidemiological studies examining the relationship between prevalence of respiratory illness and pollution.<ref name=Johnston>{{cite journal |author=Johnston NW; Sears MR |title=The epidemiology of asthma exacerbations |journal=Thorax |volume=61 |issue=8 |pages=722-728 |year=2006 |pmid=16877691 |pmc=2104697 |url=http://thorax.bmj.com/cgi/content/abstract/61/8/722?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1=Johnston+N&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT}}</ref>. From 2004-2005, the institute was relocated to four floors of the brand new Juravinski Innovation Tower, where more modern research laboratories and expanded clinical facilities were available.<ref name="firhhist" />
Founded in 1978 as the Firestone Regional Chest and Allergy Unit(FRCAU), the institute was designated as the Regional Referral Center by the District Health Council. The institute has maintained this designation, and as of 2006, it services the Hamilton Niagara Haldimand Brant Local Health Integration Network, a community of 1.4 million people. <ref name=firhhist>{{citation|title= Firestone Institute for Respiratory Health: History |url= http://www.firh.ca/Documents/firh_history.htm |accessdate= 2009-02-07 }}</ref> The institute's research developed in collaboration with clinical activities in order to comprehensively investigate mechanisms and outcomes. Accordingly, a number of [[asthma]] and [[Chronic obstructive pulmonary disease|COPD]] initiatives were launched, including the development of standardized techniques for symptom assessment, airflow limitation and [[bronchial hyperresponsiveness]]. Further investigations have included studies of exercise and allergen-induced bronchoconstriction as well as epidemiological studies examining the relationship between prevalence of respiratory illness and pollution.<ref name=Johnston>{{cite journal |author=Johnston NW; Sears MR |title=The epidemiology of asthma exacerbations |journal=Thorax |volume=61 |issue=8 |pages=722–728 |year=2006 |pmid=16877691 |pmc=2104697 |url=http://thorax.bmj.com/cgi/content/abstract/61/8/722?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1=Johnston+N&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT}}</ref>. From 2004-2005, the institute was relocated to four floors of the brand new Juravinski Innovation Tower, where more modern research laboratories and expanded clinical facilities were available.<ref name="firhhist" />


In early March 2009, Firestone researchers demonstrated that an experimental drug, [[mepolizumab]] can help reduce [[eosinophil]] production in sufferers of severe asthma.<ref>{{cite news |first=Paul |last=Taylor |title=Asthma Control |url=http://www.theglobeandmail.com/servlet/story/RTGAM.20090306.wldoses06/BNStory/specialScienceandHealth/ |work=The Globe and Mail |publisher=CTV Globe Media |location=Toronto |date= 6 March 2009 |accessdate=10 March 2009 |language=English}}</ref> The study, published in the [[New_England_Journal_of_Medicine|New England Journal of Medicine]] found that treatment with mepolizumab allowed these patients to cut back on treatments of [[prednisone]].
In early March 2009, Firestone researchers demonstrated that an experimental drug, [[mepolizumab]] can help reduce [[eosinophil]] production in sufferers of severe asthma.<ref>{{cite news |first=Paul |last=Taylor |title=Asthma Control |url=http://www.theglobeandmail.com/servlet/story/RTGAM.20090306.wldoses06/BNStory/specialScienceandHealth/ |work=The Globe and Mail |publisher=CTV Globe Media |location=Toronto |date= 6 March 2009 |accessdate=10 March 2009 }}</ref> The study, published in the [[New_England_Journal_of_Medicine|New England Journal of Medicine]] found that treatment with mepolizumab allowed these patients to cut back on treatments of [[prednisone]].


==Education==
==Education==

Revision as of 14:11, 18 December 2009

Firestone Institute for Respiratory Health
Formation1978
Location
Region served
Hamilton Niagara Haldimand Brant
Official language
English
Exec. Director
Dr. Paul O'Byrne
AffiliationsSt. Joseph's Healthcare
Staff30+
Websitefirh.ca

The Firestone Institute for Respiratory Health (FIRH) is a world-renowned center for the investigation and treatment of respiratory diseases. Based out of St. Joseph's Healthcare in Hamilton, Ontario, Canada, the institute is a clinical facility with strong research directions. FIRH faculty are also heavily involved at McMaster University with education at the undergraduate, graduate, post-graduate and continuing medical education levels.

History

Founded in 1978 as the Firestone Regional Chest and Allergy Unit(FRCAU), the institute was designated as the Regional Referral Center by the District Health Council. The institute has maintained this designation, and as of 2006, it services the Hamilton Niagara Haldimand Brant Local Health Integration Network, a community of 1.4 million people. [1] The institute's research developed in collaboration with clinical activities in order to comprehensively investigate mechanisms and outcomes. Accordingly, a number of asthma and COPD initiatives were launched, including the development of standardized techniques for symptom assessment, airflow limitation and bronchial hyperresponsiveness. Further investigations have included studies of exercise and allergen-induced bronchoconstriction as well as epidemiological studies examining the relationship between prevalence of respiratory illness and pollution.[2]. From 2004-2005, the institute was relocated to four floors of the brand new Juravinski Innovation Tower, where more modern research laboratories and expanded clinical facilities were available.[1]

In early March 2009, Firestone researchers demonstrated that an experimental drug, mepolizumab can help reduce eosinophil production in sufferers of severe asthma.[3] The study, published in the New England Journal of Medicine found that treatment with mepolizumab allowed these patients to cut back on treatments of prednisone.

Education

The FIRH has trained over 100 graduate students and post-doctoral fellows. In addition to this, the FIRH faculty currently teach numerous undergraduate and postgraduate courses at McMaster University.[4]

Research Pursuits

The following is a list of the research areas currently being investigated at the FIRH:[5]

  • Population studies of asthma epidemiology and causation
  • Studies of asthma management utilizing biomarkers of inflammation
  • Investigation of novel pharmaceutical therapies for asthma
  • Investigation of novel procedural therapies for asthma and COPD
  • Mechanisms of airway hyperresponsiveness and airway remodelling
  • Trafficking and lung homing of bone-marrow derived hemopoietic stem cells in allergic asthma and COPD
  • Immunobiology of allergic asthma
  • Control of airway and vascular smooth muscle structure, function and intracellular signalling
  • COPD epidemiology and treatment
  • COPD and Respiratory Rehabilitation
  • Pathobiology of pulmonary fibrosis
  • Clinical trial center for idiopathic pulmonary fibrosis
  • Functional and structural imaging of the lung
  • Chronic cough

References

  1. ^ a b Firestone Institute for Respiratory Health: History, retrieved 2009-02-07
  2. ^ Johnston NW; Sears MR (2006). "The epidemiology of asthma exacerbations". Thorax. 61 (8): 722–728. PMC 2104697. PMID 16877691.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ Taylor, Paul (6 March 2009). "Asthma Control". The Globe and Mail. Toronto: CTV Globe Media. Retrieved 10 March 2009.
  4. ^ Firestone Institute for Respiratory Health: About FIRH, retrieved 2009-02-07
  5. ^ Firestone Institute for Respiratory Health: Research Interests, retrieved 2009-02-07

Retrieved from "https://en.wikipedia.org/enwiki/w/index.php?title=Firestone_Institute_for_Respiratory_Health&oldid=332492149"