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:[[Catenin|Catenin: <small>proteins found in complexes with cadherin cell adhesion molecules of animal cells</small>]]
:[[Catenin|Catenin: <small>proteins found in complexes with cadherin cell adhesion molecules of animal cells</small>]]
:[[Cadherin|Cadherin: <small>(Calcium-dependent adhesion molecules) are a class of type-1 transmembrane proteins. Important in cell adhesion, ensuring that cells within tissues are bound together.</small>]]
:[[Cadherin|Cadherin: <small>(Calcium-dependent adhesion molecules) are a class of type-1 transmembrane proteins. Important in cell adhesion, ensuring that cells within tissues are bound together.</small>]]
:[[Neuroligin|Neuroligin: <small>a postsynaptic protein that helps to glue together neurons at the synapse (implicated in autism +)</small>]]
:[[Neuroligin|Neuroligin]]
:[[Synaptogenesis|Synaptogenesis]]
:[[Synaptogenesis|Synaptogenesis: <small>the formation of synapses</small>]]
:[[G-protein|G-protein: <small>(guanine nucleotide-binding proteins) are a family of proteins involved in transmitting chemical signals outside the cell, and causing changes inside the cell; communicate signals from many hormones, neurotransmitters, and other signaling factors</small>]]
:[[G-protein|G-protein]]
:[[Gamma-Aminobutyric_acid|GABA: <small>Plays a role in regulating neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone. In insect species GABA acts only on excitatory nerve receptors.</small>]]
:[[Gamma-Aminobutyric_acid|GABA]]
:[[Complexin|Complexin: <small>a nerve tissue protein bound to the SNARE protein complex; transport vesicle protein synaptotagmin, among others, in the presence of Ca2+, displaces complexin allowing the SNARE protein complex to bind the transport vesicle to the presynaptic membrane</small>]]
:[[Complexin|Complexin]]
:[[N-ethylmaleimide_sensitive_fusion_protein|N-ethylmaleimide_sensitive_fusion_protein]]
:[[N-ethylmaleimide_sensitive_fusion_protein|N-ethylmaleimide_sensitive_fusion_protein]]
:[[SNARE_(protein)|SNARE_(protein)]]
:[[SNARE_(protein)|SNARE_(protein)]]

Revision as of 23:13, 17 July 2010

Basic Neuroscience

Learning Neuroscience

Creating a Wikibook Notes
Books for experts
general 1
BDNF: neurotrophin, acts by binding to cell receptors TrkB ("Track B") and LNGFR (low-affinity nerve growth factor receptor, or p75) and modulating transmission
NGF: small secreted protein which is important for the growth, maintenance, and survival of certain target neurons (nerve cells)
Neurotrophin: part of a class of growth factors, secreted proteins, capable of signaling particular cells to survive, differentiate, or grow
CASK: Calcium/calmodulin-dependent Serine protein Kinase - is a multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking
Scaffold_protein: not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes
Wnt signaling pathway: Wg (wingless) and Int (Integration) sites of mouse mammary tumor virus (MMTV) - a network of proteins involved in embryogenesis, cancer, and normal physiological function
DLG4 or PSD-95 Disks Large homoloG 4 (DLG4 gene), recruited into NMDA receptor and K channel clusters
Catenin: proteins found in complexes with cadherin cell adhesion molecules of animal cells
Cadherin: (Calcium-dependent adhesion molecules) are a class of type-1 transmembrane proteins. Important in cell adhesion, ensuring that cells within tissues are bound together.
Neuroligin: a postsynaptic protein that helps to glue together neurons at the synapse (implicated in autism +)
Synaptogenesis: the formation of synapses
G-protein: (guanine nucleotide-binding proteins) are a family of proteins involved in transmitting chemical signals outside the cell, and causing changes inside the cell; communicate signals from many hormones, neurotransmitters, and other signaling factors
GABA: Plays a role in regulating neuronal excitability throughout the nervous system. In humans, GABA is also directly responsible for the regulation of muscle tone. In insect species GABA acts only on excitatory nerve receptors.
Complexin: a nerve tissue protein bound to the SNARE protein complex; transport vesicle protein synaptotagmin, among others, in the presence of Ca2+, displaces complexin allowing the SNARE protein complex to bind the transport vesicle to the presynaptic membrane
N-ethylmaleimide_sensitive_fusion_protein
SNARE_(protein)
SNAP-25
Synaptotagmin
VAMP Vesicle-associated_membrane_protein
Synaptobrevin
AMPAR
SNARE_proteins
Green_fluorescent_protein
Bromophenol_blue
Noggin
EGTA_(chemical)
Secretagogue
GTPgammaS
Acetylcholinesterase_inhibitors
Nernst_equation
Imide
Arabidopsis
Saccharomyces_cerevisiae
Agonist
Arachidonic_acid
PIP2
Oligomer
PI3K
Protein_kinase_A
Calmodulin
Thiol
Chelation
Peroxisome
Refractory_period_(physiology)
Vesicular monoamine transporter (VMAT): a transport protein integrated into the membrane of intracellular vesicles of presynaptic neurons, to transport monoamines into the synaptic vesicles
Selective serotonin reuptake inhibitor (SSRI) increase the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell


background physics
Siemens_(unit)
RC_circuit
neurotransmitters
Neurotransmitters
Acetylcholine
Glutamate most common 90%
GABA, gamma aminobutyric acid common
Acetylcholine
Epinephrine or Adrenaline:hormone and neurotransmitter, produced increases heart rate, contracts blood vessels, dilates air passages and participates in the fight-or-flight response of the sympathetic nervous system
Norepinephrine or NE or Noradrenaline
Glycine: an inhibitory neurotransmitter in the CNS, especially in the spinal cord, brainstem, and retina
Substance P: an undecapeptide, neuropeptide functions as a neurotransmitter and as a neuromodulator, found in the brain and spinal cord, and is associated with inflammatory processes and pain
neurotransmitters uptake / degrade
Monoamine_oxidase (MAO):a family of enzymes that catalyze the oxidation of monoamines, found bound to the outer membrane of mitochondria
Catechol-O-methyl transferase:one of several enzymes that degrade catecholamines such as dopamine, epinephrine, and norepinephrine


receptors
Metabotropic receptor: are indirectly linked with ion-channels on the plasma membrane of the cell through signal transduction mechanisms, often G proteins
Ionotropic receptor: a group of trans-membrane ion channels that are opened or closed in response to the binding of a chemical messenger (i.e., a ligand), such as a neurotransmitter
G protein coupled receptor (GPCRs)
Ligand gated ion channel (LGIC)
Glutamate_receptor
Metabotropic glutamate receptor
NMDA receptor: ionotropic glutamate receptor, noted for voltage-dependent activation, a result of ion channel block by extracellular Mg2+ ions
AMPA receptor: non-NMDA ionotropic glutamate receptors, mediates fast synaptic transmission in CNS
Kainate receptor: non-NMDA ionotropic glutamate receptors
Receptor_tyrosine_kinase
GABA_receptor
GABA A receptor: ionotropic, ligand gated
GABAB receptor: metabotropic
Glycine_receptor
Muscarinic acetylcholine receptor: metabotropic
Nicotinic acetylcholine receptor: ionotropic
Serotonin receptor, 5-HT 5-hydroxytryptamine receptors a group of G protein-coupled receptors (GPCRs) except 5-HT3 receptor, a ligand-gated ion channel
Adrenergic receptor: class of G protein-coupled catecholamine receptors, (esp. norepinephrine and epinephrine), not dopamine (also a catecholamine)
Dopamine receptor:
Histamine receptor: G protein-coupled receptors with histamine as their endogenous ligand
Cannabinoid receptor type 1, (CB1) widely expressed G protein-coupled receptors, act as endocannabinoid-mediated depolarization-induced suppression of inhibition, common plasticity
various interesting
Cognitive_enhancers
Modafinil