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'''BAG family molecular chaperone regulator 1''' is a [[protein]] that in humans is encoded by the ''BAG1'' [[gene]].<ref name="pmid7834747">{{cite journal | author = Takayama S, Sato T, Krajewski S, Kochel K, Irie S, Millan JA, Reed JC | title = Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity | journal = Cell | volume = 80 | issue = 2 | pages = 279–84 | year = 1995 | month = Mar | pmid = 7834747 | pmc = | doi = }}</ref> |
'''BAG family molecular chaperone regulator 1''' is a [[protein]] that in humans is encoded by the ''BAG1'' [[gene]].<ref name="pmid7834747">{{cite journal | author = Takayama S, Sato T, Krajewski S, Kochel K, Irie S, Millan JA, Reed JC | title = Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity | journal = Cell | volume = 80 | issue = 2 | pages = 279–84 | year = 1995 | month = Mar | pmid = 7834747 | pmc = | doi =10.1016/0092-8674(95)90410-7 }}</ref> |
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==Interactions== |
==Interactions== |
||
BAG1 has been shown to [[Protein-protein_interaction|interact]] with [[Retinoic acid receptor alpha]],<ref name=pmid9642262>{{cite journal |last=Liu |first=R |authorlink= |coauthors=Takayama S, Zheng Y, Froesch B, Chen G Q, Zhang X, Reed J C, Zhang X K |year=[[1998]]|month=Jul. |title=Interaction of BAG-1 with retinoic acid receptor and its inhibition of retinoic acid-induced apoptosis in cancer cells |journal=J. Biol. Chem. |volume=273 |issue=27 |pages=16985–92 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9642262 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[C-Raf]],<ref name=pmid8692945>{{cite journal |last=Wang |first=H G |authorlink= |coauthors=Takayama S, Rapp U R, Reed J C |year=[[1996]]|month=Jul. |title=Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1 |journal=[[PNAS|Proc. Natl. Acad. Sci. U.S.A.]] |volume=93 |issue=14 |pages=7063–8 |publisher= |location = UNITED STATES| issn = 0027-8424| pmid = 8692945 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=38936 }}</ref> [[PPP1R15A]],<ref name=pmid12724406>{{cite journal |last=Hung |first=Wesley J |authorlink= |coauthors=Roberson Rachel S, Taft Jaime, Wu Daniel Y |year=[[2003]]|month=May. |title=Human BAG-1 proteins bind to the cellular stress response protein GADD34 and interfere with GADD34 functions |journal=Mol. Cell. Biol. |volume=23 |issue=10 |pages=3477–86 |publisher= |location = United States| issn = 0270-7306| pmid = 12724406 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=164759 }}</ref> [[Androgen receptor]],<ref name=pmid14517289>{{cite journal |last=Shatkina |first=Liubov |authorlink= |coauthors=Mink Sigrun, Rogatsch Hermann, Klocker Helmut, Langer Gernot, Nestl Andrea, Cato Andrew C B |year=[[2003]]|month=Oct. |title=The cochaperone Bag-1L enhances androgen receptor action via interaction with the NH2-terminal region of the receptor |journal=Mol. Cell. Biol. |volume=23 |issue=20 |pages=7189–97 |publisher= |location = United States| issn = 0270-7306| pmid = 14517289 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=230325 }}</ref><ref name=pmid11278763>{{cite journal |last=Knee |first=D A |authorlink= |coauthors=Froesch B A, Nuber U, Takayama S, Reed J C |year=[[2001]]|month=Apr. |title=Structure-function analysis of Bag1 proteins. Effects on androgen receptor transcriptional activity |journal=J. Biol. Chem. |volume=276 |issue=16 |pages=12718–24 |publisher= |location = United States| issn = 0021-9258| pmid = 11278763 |doi = 10.1074/jbc.M010841200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid9565586>{{cite journal |last=Froesch |first=B A |authorlink= |coauthors=Takayama S, Reed J C |year=[[1998]]|month=May. |title=BAG-1L protein enhances androgen receptor function |journal=J. Biol. Chem. |volume=273 |issue=19 |pages=11660–6 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9565586 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[HSPA8]],<ref name=pmid9305631>{{cite journal |last=Takayama |first=S |authorlink= |coauthors=Bimston D N, Matsuzawa S, Freeman B C, Aime-Sempe C, Xie Z, Morimoto R I, Reed J C |year=[[1997]]|month=Aug. |title=BAG-1 modulates the chaperone activity of Hsp70/Hsc70 |journal=EMBO J. |volume=16 |issue=16 |pages=4887–96 |publisher= |location = ENGLAND| issn = 0261-4189| pmid = 9305631 |doi = 10.1093/emboj/16.16.4887 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=1170124 }}</ref><ref name=pmid9873016>{{cite journal |last=Takayama |first=S |authorlink= |coauthors=Xie Z, Reed J C |year=[[1999]]|month=Jan. |title=An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators |journal=J. Biol. Chem. |volume=274 |issue=2 |pages=781–6 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9873016 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[Heparin-binding EGF-like growth factor]],<ref name=pmid11340068>{{cite journal |last=Lin |first=J |authorlink= |coauthors=Hutchinson L, Gaston S M, Raab G, Freeman M R |year=[[2001]]|month=Aug. |title=BAG-1 is a novel cytoplasmic binding partner of the membrane form of heparin-binding EGF-like growth factor: a unique role for proHB-EGF in cell survival regulation |journal=J. Biol. Chem. |volume=276 |issue=32 |pages=30127–32 |publisher= |location = United States| issn = 0021-9258| pmid = 11340068 |doi = 10.1074/jbc.M010237200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[Glucocorticoid receptor]],<ref name=pmid9603979>{{cite journal |last=Kullmann |first=M |authorlink= |coauthors=Schneikert J, Moll J, Heck S, Zeiner M, Gehring U, Cato A C |year=[[1998]]|month=Jun. |title=RAP46 is a negative regulator of glucocorticoid receptor action and hormone-induced apoptosis |journal=J. Biol. Chem. |volume=273 |issue=23 |pages=14620–5 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9603979 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid11101523>{{cite journal |last=Schneikert |first=J |authorlink= |coauthors=Hübner S, Langer G, Petri T, Jäättelä M, Reed J, Cato A C |year=[[2000]]|month=Dec. |title=Hsp70-RAP46 interaction in downregulation of DNA binding by glucocorticoid receptor |journal=EMBO J. |volume=19 |issue=23 |pages=6508–16 |publisher= |location = ENGLAND| issn = 0261-4189| pmid = 11101523 |doi = 10.1093/emboj/19.23.6508 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=305849 }}</ref> [[Calcitriol receptor]]<ref name=pmid10967105>{{cite journal |last=Guzey |first=M |authorlink= |coauthors=Takayama S, Reed J C |year=[[2000]]|month=Dec. |title=BAG1L enhances trans-activation function of the vitamin D receptor |journal=J. Biol. Chem. |volume=275 |issue=52 |pages=40749–56 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 10967105 |doi = 10.1074/jbc.M004977200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[SIAH1]].<ref name=pmid9582267>{{cite journal |last=Matsuzawa |first=S |authorlink= |coauthors=Takayama S, Froesch B A, Zapata J M, Reed J C |year=[[1998]]|month=May. |title=p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1 |journal=EMBO J. |volume=17 |issue=10 |pages=2736–47 |publisher= |location = ENGLAND| issn = 0261-4189| pmid = 9582267 |doi = 10.1093/emboj/17.10.2736 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=1170614 }}</ref> |
BAG1 has been shown to [[Protein-protein_interaction|interact]] with [[Retinoic acid receptor alpha]],<ref name=pmid9642262>{{cite journal |doi=10.1074/jbc.273.27.16985 |last=Liu |first=R |authorlink= |coauthors=Takayama S, Zheng Y, Froesch B, Chen G Q, Zhang X, Reed J C, Zhang X K |year=[[1998]]|month=Jul. |title=Interaction of BAG-1 with retinoic acid receptor and its inhibition of retinoic acid-induced apoptosis in cancer cells |journal=J. Biol. Chem. |volume=273 |issue=27 |pages=16985–92 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9642262 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[C-Raf]],<ref name=pmid8692945>{{cite journal |doi=10.1073/pnas.93.14.7063 |last=Wang |first=H G |authorlink= |coauthors=Takayama S, Rapp U R, Reed J C |year=[[1996]]|month=Jul. |title=Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1 |journal=[[PNAS|Proc. Natl. Acad. Sci. U.S.A.]] |volume=93 |issue=14 |pages=7063–8 |publisher= |location = UNITED STATES| issn = 0027-8424| pmid = 8692945 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=38936 }}</ref> [[PPP1R15A]],<ref name=pmid12724406>{{cite journal |doi=10.1128/MCB.23.10.3477-3486.2003 |last=Hung |first=Wesley J |authorlink= |coauthors=Roberson Rachel S, Taft Jaime, Wu Daniel Y |year=[[2003]]|month=May. |title=Human BAG-1 proteins bind to the cellular stress response protein GADD34 and interfere with GADD34 functions |journal=Mol. Cell. Biol. |volume=23 |issue=10 |pages=3477–86 |publisher= |location = United States| issn = 0270-7306| pmid = 12724406 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=164759 }}</ref> [[Androgen receptor]],<ref name=pmid14517289>{{cite journal |doi=10.1128/MCB.23.20.7189-7197.2003 |last=Shatkina |first=Liubov |authorlink= |coauthors=Mink Sigrun, Rogatsch Hermann, Klocker Helmut, Langer Gernot, Nestl Andrea, Cato Andrew C B |year=[[2003]]|month=Oct. |title=The cochaperone Bag-1L enhances androgen receptor action via interaction with the NH2-terminal region of the receptor |journal=Mol. Cell. Biol. |volume=23 |issue=20 |pages=7189–97 |publisher= |location = United States| issn = 0270-7306| pmid = 14517289 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=230325 }}</ref><ref name=pmid11278763>{{cite journal |last=Knee |first=D A |authorlink= |coauthors=Froesch B A, Nuber U, Takayama S, Reed J C |year=[[2001]]|month=Apr. |title=Structure-function analysis of Bag1 proteins. Effects on androgen receptor transcriptional activity |journal=J. Biol. Chem. |volume=276 |issue=16 |pages=12718–24 |publisher= |location = United States| issn = 0021-9258| pmid = 11278763 |doi = 10.1074/jbc.M010841200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid9565586>{{cite journal |doi=10.1074/jbc.273.19.11660 |last=Froesch |first=B A |authorlink= |coauthors=Takayama S, Reed J C |year=[[1998]]|month=May. |title=BAG-1L protein enhances androgen receptor function |journal=J. Biol. Chem. |volume=273 |issue=19 |pages=11660–6 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9565586 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[HSPA8]],<ref name=pmid9305631>{{cite journal |last=Takayama |first=S |authorlink= |coauthors=Bimston D N, Matsuzawa S, Freeman B C, Aime-Sempe C, Xie Z, Morimoto R I, Reed J C |year=[[1997]]|month=Aug. |title=BAG-1 modulates the chaperone activity of Hsp70/Hsc70 |journal=EMBO J. |volume=16 |issue=16 |pages=4887–96 |publisher= |location = ENGLAND| issn = 0261-4189| pmid = 9305631 |doi = 10.1093/emboj/16.16.4887 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=1170124 }}</ref><ref name=pmid9873016>{{cite journal |doi=10.1074/jbc.274.2.781 |last=Takayama |first=S |authorlink= |coauthors=Xie Z, Reed J C |year=[[1999]]|month=Jan. |title=An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators |journal=J. Biol. Chem. |volume=274 |issue=2 |pages=781–6 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9873016 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[Heparin-binding EGF-like growth factor]],<ref name=pmid11340068>{{cite journal |last=Lin |first=J |authorlink= |coauthors=Hutchinson L, Gaston S M, Raab G, Freeman M R |year=[[2001]]|month=Aug. |title=BAG-1 is a novel cytoplasmic binding partner of the membrane form of heparin-binding EGF-like growth factor: a unique role for proHB-EGF in cell survival regulation |journal=J. Biol. Chem. |volume=276 |issue=32 |pages=30127–32 |publisher= |location = United States| issn = 0021-9258| pmid = 11340068 |doi = 10.1074/jbc.M010237200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> [[Glucocorticoid receptor]],<ref name=pmid9603979>{{cite journal |doi=10.1074/jbc.273.23.14620 |last=Kullmann |first=M |authorlink= |coauthors=Schneikert J, Moll J, Heck S, Zeiner M, Gehring U, Cato A C |year=[[1998]]|month=Jun. |title=RAP46 is a negative regulator of glucocorticoid receptor action and hormone-induced apoptosis |journal=J. Biol. Chem. |volume=273 |issue=23 |pages=14620–5 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 9603979 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref><ref name=pmid11101523>{{cite journal |last=Schneikert |first=J |authorlink= |coauthors=Hübner S, Langer G, Petri T, Jäättelä M, Reed J, Cato A C |year=[[2000]]|month=Dec. |title=Hsp70-RAP46 interaction in downregulation of DNA binding by glucocorticoid receptor |journal=EMBO J. |volume=19 |issue=23 |pages=6508–16 |publisher= |location = ENGLAND| issn = 0261-4189| pmid = 11101523 |doi = 10.1093/emboj/19.23.6508 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=305849 }}</ref> [[Calcitriol receptor]]<ref name=pmid10967105>{{cite journal |last=Guzey |first=M |authorlink= |coauthors=Takayama S, Reed J C |year=[[2000]]|month=Dec. |title=BAG1L enhances trans-activation function of the vitamin D receptor |journal=J. Biol. Chem. |volume=275 |issue=52 |pages=40749–56 |publisher= |location = UNITED STATES| issn = 0021-9258| pmid = 10967105 |doi = 10.1074/jbc.M004977200 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}</ref> and [[SIAH1]].<ref name=pmid9582267>{{cite journal |last=Matsuzawa |first=S |authorlink= |coauthors=Takayama S, Froesch B A, Zapata J M, Reed J C |year=[[1998]]|month=May. |title=p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1 |journal=EMBO J. |volume=17 |issue=10 |pages=2736–47 |publisher= |location = ENGLAND| issn = 0261-4189| pmid = 9582267 |doi = 10.1093/emboj/17.10.2736 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=1170614 }}</ref> |
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==References== |
==References== |
Revision as of 12:45, 4 August 2010
Template:PBB BAG family molecular chaperone regulator 1 is a protein that in humans is encoded by the BAG1 gene.[1]
BAG gene has been implicated in age related neurodegenerative diseases as Alzheimer's. It has been demonstrated that BAG1 and BAG 3 regulate the proteasomal and lysosomal protein elimination pathways, respectively.[2]
Interactions
BAG1 has been shown to interact with Retinoic acid receptor alpha,[3] C-Raf,[4] PPP1R15A,[5] Androgen receptor,[6][7][8] HSPA8,[9][10] Heparin-binding EGF-like growth factor,[11] Glucocorticoid receptor,[12][13] Calcitriol receptor[14] and SIAH1.[15]
References
- ^ Takayama S, Sato T, Krajewski S, Kochel K, Irie S, Millan JA, Reed JC (1995). "Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity". Cell. 80 (2): 279–84. doi:10.1016/0092-8674(95)90410-7. PMID 7834747.
{{cite journal}}
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- ^ Liu, R (1998). "Interaction of BAG-1 with retinoic acid receptor and its inhibition of retinoic acid-induced apoptosis in cancer cells". J. Biol. Chem. 273 (27). UNITED STATES: 16985–92. doi:10.1074/jbc.273.27.16985. ISSN 0021-9258. PMID 9642262.
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ignored (|author=
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ignored (help)CS1 maint: unflagged free DOI (link) CS1 maint: year (link) - ^ Wang, H G (1996). "Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1". Proc. Natl. Acad. Sci. U.S.A. 93 (14). UNITED STATES: 7063–8. doi:10.1073/pnas.93.14.7063. ISSN 0027-8424. PMC 38936. PMID 8692945.
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ignored (help)CS1 maint: year (link) - ^ Hung, Wesley J (2003). "Human BAG-1 proteins bind to the cellular stress response protein GADD34 and interfere with GADD34 functions". Mol. Cell. Biol. 23 (10). United States: 3477–86. doi:10.1128/MCB.23.10.3477-3486.2003. ISSN 0270-7306. PMC 164759. PMID 12724406.
{{cite journal}}
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, and|laysource=
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ignored (help)CS1 maint: year (link) - ^ Shatkina, Liubov (2003). "The cochaperone Bag-1L enhances androgen receptor action via interaction with the NH2-terminal region of the receptor". Mol. Cell. Biol. 23 (20). United States: 7189–97. doi:10.1128/MCB.23.20.7189-7197.2003. ISSN 0270-7306. PMC 230325. PMID 14517289.
{{cite journal}}
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, and|laysource=
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suggested) (help); Unknown parameter|month=
ignored (help)CS1 maint: year (link) - ^ Knee, D A (2001). "Structure-function analysis of Bag1 proteins. Effects on androgen receptor transcriptional activity". J. Biol. Chem. 276 (16). United States: 12718–24. doi:10.1074/jbc.M010841200. ISSN 0021-9258. PMID 11278763.
{{cite journal}}
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, and|laysource=
(help); Unknown parameter|coauthors=
ignored (|author=
suggested) (help); Unknown parameter|month=
ignored (help)CS1 maint: unflagged free DOI (link) CS1 maint: year (link) - ^ Froesch, B A (1998). "BAG-1L protein enhances androgen receptor function". J. Biol. Chem. 273 (19). UNITED STATES: 11660–6. doi:10.1074/jbc.273.19.11660. ISSN 0021-9258. PMID 9565586.
{{cite journal}}
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, and|laysource=
(help); Unknown parameter|coauthors=
ignored (|author=
suggested) (help); Unknown parameter|month=
ignored (help)CS1 maint: unflagged free DOI (link) CS1 maint: year (link) - ^ Takayama, S (1997). "BAG-1 modulates the chaperone activity of Hsp70/Hsc70". EMBO J. 16 (16). ENGLAND: 4887–96. doi:10.1093/emboj/16.16.4887. ISSN 0261-4189. PMC 1170124. PMID 9305631.
{{cite journal}}
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ignored (help)CS1 maint: year (link) - ^ Takayama, S (1999). "An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators". J. Biol. Chem. 274 (2). UNITED STATES: 781–6. doi:10.1074/jbc.274.2.781. ISSN 0021-9258. PMID 9873016.
{{cite journal}}
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ignored (help)CS1 maint: unflagged free DOI (link) CS1 maint: year (link) - ^ Lin, J (2001). "BAG-1 is a novel cytoplasmic binding partner of the membrane form of heparin-binding EGF-like growth factor: a unique role for proHB-EGF in cell survival regulation". J. Biol. Chem. 276 (32). United States: 30127–32. doi:10.1074/jbc.M010237200. ISSN 0021-9258. PMID 11340068.
{{cite journal}}
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(help); Unknown parameter|coauthors=
ignored (|author=
suggested) (help); Unknown parameter|month=
ignored (help)CS1 maint: unflagged free DOI (link) CS1 maint: year (link) - ^ Kullmann, M (1998). "RAP46 is a negative regulator of glucocorticoid receptor action and hormone-induced apoptosis". J. Biol. Chem. 273 (23). UNITED STATES: 14620–5. doi:10.1074/jbc.273.23.14620. ISSN 0021-9258. PMID 9603979.
{{cite journal}}
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ignored (help)CS1 maint: unflagged free DOI (link) CS1 maint: year (link) - ^ Schneikert, J (2000). "Hsp70-RAP46 interaction in downregulation of DNA binding by glucocorticoid receptor". EMBO J. 19 (23). ENGLAND: 6508–16. doi:10.1093/emboj/19.23.6508. ISSN 0261-4189. PMC 305849. PMID 11101523.
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ignored (help)CS1 maint: year (link) - ^ Guzey, M (2000). "BAG1L enhances trans-activation function of the vitamin D receptor". J. Biol. Chem. 275 (52). UNITED STATES: 40749–56. doi:10.1074/jbc.M004977200. ISSN 0021-9258. PMID 10967105.
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