Acantholysis: Difference between revisions
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'''Acantholysis''' is the loss of [[Cell junction|intercellular connections]], such as [[desmosomes]], resulting in loss of cohesion between [[keratinocyte]]s<ref name="Kumar">Kumar, Vinay; Fausto, Nelso; Abbas, Abul (2004) ''Robbins & Cotran Pathologic Basis of Disease'' (7th ed.). Saunders. Page 1230. ISBN 0-7216-0187-1.</ref>, seen in diseases such as [[pemphigus vulgaris]].<ref>[http://www.medilexicon.com/medicaldictionary.php?t=375 Medical Dictionary Entry]</ref> It is absent in [[bullous pemphigoid]], making it useful for [[differential diagnosis]]. |
'''Acantholysis''' is the loss of [[Cell junction|intercellular connections]], such as [[desmosomes]], resulting in loss of cohesion between [[keratinocyte]]s<ref name="Kumar">Kumar, Vinay; Fausto, Nelso; Abbas, Abul (2004) ''Robbins & Cotran Pathologic Basis of Disease'' (7th ed.). Saunders. Page 1230. ISBN 0-7216-0187-1.</ref>, seen in diseases such as [[pemphigus vulgaris]].<ref>[http://www.medilexicon.com/medicaldictionary.php?t=375 Medical Dictionary Entry]</ref> It is absent in [[bullous pemphigoid]], making it useful for [[differential diagnosis]]. |
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This [[Histology|histological]] feature is also seen in [[Herpes simplex#Signs and |
This [[Histology|histological]] feature is also seen in [[Herpes simplex#Signs and symptoms|herpes simplex infections]] (HSV 1 and 2). |
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== See also == |
== See also == |
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Revision as of 06:47, 23 October 2010
| Acantholysis | |
|---|---|
| Specialty | Dermatology  |
Acantholysis is the loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes[1], seen in diseases such as pemphigus vulgaris.[2] It is absent in bullous pemphigoid, making it useful for differential diagnosis.
This histological feature is also seen in herpes simplex infections (HSV 1 and 2).
See also
References
- ^ Kumar, Vinay; Fausto, Nelso; Abbas, Abul (2004) Robbins & Cotran Pathologic Basis of Disease (7th ed.). Saunders. Page 1230. ISBN 0-7216-0187-1.
- ^ Medical Dictionary Entry