JWH-307: Difference between revisions
Content deleted Content added
No edit summary |
mNo edit summary |
||
| Line 27: | Line 27: | ||
'''JWH-307''' is an [[analgesic]] drug used in scientific research, which acts as a [[cannabinoid]] agonist at both the [[cannabinoid receptor 1|CB<sub>1</sub>]] and [[cannabinoid receptor 2|CB<sub>2</sub>]] [[Receptor (biochemistry)|receptors]]. It is somewhat selective for the CB<sub>2</sub> subtype, with a [[Dissociation constant|Ki]] of 7.7nM at CB<sub>1</sub> vs 3.3nM at CB<sub>2</sub>.<ref>Huffman JW, Padgett LW, Isherwood ML, Wiley JL, Martin BR. 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: New high affinity ligands for the cannabinoid CB<sub>1</sub> and CB<sub>2</sub> receptors. ''Bioorganic & Medicinal Chemistry Letters'' 2006; 16:5432-5435.</ref> It was discovered by, and named after, Dr. [[John W. Huffman]]. |
'''JWH-307''' is an [[analgesic]] drug used in scientific research, which acts as a [[cannabinoid]] agonist at both the [[cannabinoid receptor 1|CB<sub>1</sub>]] and [[cannabinoid receptor 2|CB<sub>2</sub>]] [[Receptor (biochemistry)|receptors]]. It is somewhat selective for the CB<sub>2</sub> subtype, with a [[Dissociation constant|Ki]] of 7.7nM at CB<sub>1</sub> vs 3.3nM at CB<sub>2</sub>.<ref>Huffman JW, Padgett LW, Isherwood ML, Wiley JL, Martin BR. 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: New high affinity ligands for the cannabinoid CB<sub>1</sub> and CB<sub>2</sub> receptors. ''Bioorganic & Medicinal Chemistry Letters'' 2006; 16:5432-5435.</ref> It was discovered by, and named after, Dr. [[John W. Huffman]]. |
||
| ⚫ | |||
==Manufacture and Sale== |
==Manufacture and Sale== |
||
*[http://www.titaniumwf.com www.titaniumwf.com Laboratory producing and selling JWH-307] |
*[http://www.titaniumwf.com www.titaniumwf.com Laboratory producing and selling JWH-307] |
||
==References== |
==References== |
||
<references/> |
<references/> |
||
| ⚫ | |||
{{Cannabinoids}} |
{{Cannabinoids}} |
||
Revision as of 17:20, 3 November 2010
 | |
| Legal status | |
|---|---|
| Legal status |
|
| Identifiers | |
| |
| PubChem CID | |
| CompTox Dashboard (EPA) | |
| Chemical and physical data | |
| Formula | C26H24FNO |
| Molar mass | 385.472 g/mol g·mol−1 |
| 3D model (JSmol) | |
| |
JWH-307 is an analgesic drug used in scientific research, which acts as a cannabinoid agonist at both the CB1 and CB2 receptors. It is somewhat selective for the CB2 subtype, with a Ki of 7.7nM at CB1 vs 3.3nM at CB2.[1] It was discovered by, and named after, Dr. John W. Huffman.
Manufacture and Sale
References
- ^ Huffman JW, Padgett LW, Isherwood ML, Wiley JL, Martin BR. 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: New high affinity ligands for the cannabinoid CB1 and CB2 receptors. Bioorganic & Medicinal Chemistry Letters 2006; 16:5432-5435.
 | This cannabinoid related article is a stub. You can help Wikipedia by expanding it. |