GV (nerve agent): Difference between revisions
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Script assisted update of identifiers from ChemSpider, CommonChemistry and FDA for the Chem/Drugbox validation project - Updated: ChemSpiderID InChI1 InChIKey1 SMILES. |
Script assisted update of identifiers from ChemSpider, CommonChemistry and FDA for the Chem/Drugbox validation project - Updated: InChI1->InChI StdInChI StdInChIKey. |
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| Section1 = {{Chembox Identifiers |
| Section1 = {{Chembox Identifiers |
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| ChemSpiderID = 112656 |
| ChemSpiderID = 112656 |
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| InChI = 1/C6H16FN2OP/c1-8(2)5-6-11(7,10)9(3)4/h5-6H2,1-4H3 |
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| InChIKey = JJHAGEZAXYOCMC-UHFFFAOYAS |
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| StdInChI = 1S/C6H16FN2OP/c1-8(2)5-6-11(7,10)9(3)4/h5-6H2,1-4H3 |
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| StdInChIKey = JJHAGEZAXYOCMC-UHFFFAOYSA-N |
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| CASNo = 141102-74-1 |
| CASNo = 141102-74-1 |
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| SMILES = FP(=O)(N(C)C)CCN(C)C |
| SMILES = FP(=O)(N(C)C)CCN(C)C |
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Revision as of 09:52, 2 December 2010
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| Names | |
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| IUPAC name
2-(dimethylamino-fluorophosphoryl)oxy-N,N-dimethylethanamine
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| Identifiers | |
3D model (JSmol)
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PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C6H16FN2O2P | |
| Molar mass | 198.176 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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GV (O-[2-(dimethylamino)ethyl]-N,N-dimethylphosphoramidic fluoride) is an organophosphate nerve agent. GV is a part of a new series of nerve agents with properties similar to both the "G-series" and "V-series". It is a potent acetylcholinesterase inhibitor with properties similar to other nerve agents, being a highly poisonous vapour. Treatment for poisoning with GV involves drugs such as atropine, benactyzine, obidoxime and HI-6.[1][2]
References
- ^ Fusek J, Bajgar J. Treatment of intoxication with GV compound in laboratory rats. Sbornik Vedeckych Praci Lekarske Fakulty Karlovy Univerzity v Hradci Kralove. 1994;37(2):57-62. PMID 7784799
- ^ Kassa J, Bajgar J. Therapeutic efficacy of obidoxime or HI-6 with atropine against intoxication with some nerve agents in mice. Acta Medica (Hradec Kralove). 1996;39(1):27-30. PMID 9106387
External links
- Identification, Purification, and Partial Characterization of the GV-Degrading Enzyme from ATCC # 29660 Alteromonas Undina
- Some Toxic Chemicals as Potential Chemical Warfare Agents - The Threat for the Future?
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