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Buphenine: Difference between revisions

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| ATC_suffix = CA02
| ATC_suffix = CA02
| PubChem = 4567
| PubChem = 4567
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 114655
| DrugBank =
| DrugBank =
|smiles = OC(c1ccc(O)cc1)C(NC(C)CCc2ccccc2)C
|smiles = OC(c1ccc(O)cc1)C(NC(C)CCc2ccccc2)C

Revision as of 15:50, 20 December 2010

{{Drugbox | IUPAC_name = 4-{1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]propyl}phenol | image = Buphenine.png | ChemSpiderID = 4407 | InChI = 1/C19H25NO2/c1-14(8-9-16-6-4-3-5-7-16)20-15(2)19(22)17-10-12-18(21)13-11-17/h3-7,10-15,19-22H,8-9H2,1-2H3 | InChIKey = PTGXAUBQBSGPKF-UHFFFAOYAE | CAS_number = 447-41-6 | ATC_prefix = G02 | ATC_suffix = CA02 | PubChem = 4567 | ChEMBL_Ref =  checkY | ChEMBL = 114655 | DrugBank = |smiles = OC(c1ccc(O)cc1)C(NC(C)CCc2ccccc2)C | C=19 | H=25 | N=1 | O=2 | molecular_weight = 299.41 g/mol | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | pregnancy_AU = | pregnancy_US = | pregnancy_category= | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = }}

Buphenine (or nylidrin) is a sympathomimetic[1] and beta-adrenergic agonist.

References

  1. ^ Mittag TW, Tormay A, Messenger M, Podos SM (1985). "Ocular hypotension in the rabbit. Receptor mechanisms of pirbuterol and nylidrin". Invest. Ophthalmol. Vis. Sci. 26 (2): 163–9. PMID 2857689. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)