Thyronamine: Difference between revisions
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Script assisted update of identifiers from ChemSpider, CommonChemistry and FDA for the Chem/Drugbox validation project - Updated: ChEMBL. |
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| verifiedrevid = |
| verifiedrevid = 418302300 |
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| ImageFile = Thyronamine.svg |
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| InChI = 1/C14H15NO2/c15-10-9-11-1-5-13(6-2-11)17-14-7-3-12(16)4-8-14/h1-8,16H,9-10,15H2 |
| InChI = 1/C14H15NO2/c15-10-9-11-1-5-13(6-2-11)17-14-7-3-12(16)4-8-14/h1-8,16H,9-10,15H2 |
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| InChIKey = OVUVNKDANCKDCK-UHFFFAOYAP |
| InChIKey = OVUVNKDANCKDCK-UHFFFAOYAP |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = 201896 |
| ChEMBL = 201896 |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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Revision as of 14:50, 11 March 2011
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| Identifiers | |
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3D model (JSmol)
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| ChEMBL | |
| ChemSpider | |
| MeSH | thyronamine |
PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C14H15NO2 | |
| Molar mass | 229.274 g mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Thyronamine refers both to a molecule, and to derivatives of that molecule: a family of decarboxylated and deiodinated metabolites of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3).
Types
The group includes:
- Thyronamine (T0AM)
- 3-Iodothyronamine (T1AM), which is the most notable one as it is a trace amine found in the nervous system. It is a possible candidate for the natural ligand of the trace amine-associated receptor TAAR1 (TAR1), a G protein-coupled receptor located in the cell membrane.
- 3,5-Diiodothyronamine (T2AM)
- 3,5,3'-Triiodothyronamine (T3AM)