REV1: Difference between revisions
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'''DNA repair protein REV1''' is a [[protein]] that in humans is encoded by the ''REV1'' [[gene]].<ref name="pmid10536157">{{cite journal | author = Lin W, Xin H, Zhang Y, Wu X, Yuan F, Wang Z | title = The human REV1 gene codes for a DNA template-dependent dCMP transferase | journal = Nucleic Acids Res | volume = 27 | issue = 22 | pages = 4468–75 | year = 1999 | month = Dec | pmid = 10536157 | pmc = 148731 | doi =10.1093/nar/27.22.4468 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: REV1 REV1 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51455| accessdate = }}</ref> Rev1 is a [[DNA polymerase #Family Y|Y family DNA polymerase]]. |
'''DNA repair protein REV1''' is a [[protein]] that in humans is encoded by the ''REV1'' [[gene]].<ref name="pmid10536157">{{cite journal | author = Lin W, Xin H, Zhang Y, Wu X, Yuan F, Wang Z | title = The human REV1 gene codes for a DNA template-dependent dCMP transferase | journal = Nucleic Acids Res | volume = 27 | issue = 22 | pages = 4468–75 | year = 1999 | month = Dec | pmid = 10536157 | pmc = 148731 | doi =10.1093/nar/27.22.4468 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: REV1 REV1 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51455| accessdate = }}</ref> Rev1 is a [[DNA polymerase #Family Y|Y family DNA polymerase]], it is sometimes referred to as a ''deoxycytidyl transferase'' because it only inserts [[deoxycytidine]] (dC) across from lesions. Whether [[Guanine|G]], [[Adenine|A]], [[Thymine|T]], [[Cytidine|C]], or an [[AP site|abasic site]], Rev1 will always add a C. |
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Revision as of 00:24, 24 May 2011
Template:PBB DNA repair protein REV1 is a protein that in humans is encoded by the REV1 gene.[1][2] Rev1 is a Y family DNA polymerase, it is sometimes referred to as a deoxycytidyl transferase because it only inserts deoxycytidine (dC) across from lesions. Whether G, A, T, C, or an abasic site, Rev1 will always add a C.
Interactions
REV1 has been shown to interact with MAD2L2.[3]
References
- ^ Lin W, Xin H, Zhang Y, Wu X, Yuan F, Wang Z (1999). "The human REV1 gene codes for a DNA template-dependent dCMP transferase". Nucleic Acids Res. 27 (22): 4468–75. doi:10.1093/nar/27.22.4468. PMC 148731. PMID 10536157.
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- ^ Murakumo, Y (2001). "Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7". J. Biol. Chem. 276 (38). United States: 35644–51. doi:10.1074/jbc.M102051200. ISSN 0021-9258. PMID 11485998.
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