Doramectin: Difference between revisions
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Revision as of 05:48, 1 July 2011
Clinical data | |
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Routes of administration | Injection, Topical and Oral |
ATCvet code | |
Legal status | |
Legal status |
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Identifiers | |
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CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.123.125 |
Chemical and physical data | |
Formula | C50H74O14 |
Molar mass | 899.114 g·mol−1 |
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Doramectin (Dectomax) is a veterinary drug approved by the Food and Drug Administration (FDA) for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in cattle.[1]
It is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites). Doramectin is a derivative of ivermectin. Its spectrum includes: Haemonchus spp., Ostertagia spp., Trichostrongylus spp., Cooperia spp., Oesophagostomum spp., Dyctiocaulus viviparus, Dermatobia hominis, Boophilus microplus, Psoroptes bovis, among many other internal and external parasites. It is available in 2 dosage forms: as an injection and as a 5 mg/ml topical solution.
Doramectin is also marketed in many Latin-American and some Asia and Africa countries as Doramec L.A. (manufactured by Agrovet Market Animal Health[2]) in an 1% Doramectin Long Acting Injectable Solution for cattle, sheep, swine[3] and others. Its oleous carrier confers to Doramec L.A. a slow and prolonged liberation, extending its action up to 42 days.
Doramectin is also available for horses[3] as an oral flavored bioadhesive gel under the name Doraquest L.A. Oral Gel.[4] It can be used to control and treat internal parasites as roundworms, lungworms and some external parasites.
References
- ^ Pfizer Animal Health. "DECTOMAX Injectable." Last accessed July 14, 2007.
- ^ Agrovet Market Animal Health-Doramec L.A.
- ^ a b Agrovet Market Animal Health
- ^ Agrovet Market Animal Health-Doraquest L.A. Oral Gel