Talk:Clomifene

abuse

Someone inserted this:

Clomifene is commonly used by male anabolic steroid users to bind the estrogen receptors in their bodies, therby blocking the effects of estrogen. It simultaniously restores the bodies natural production of testosterone. It is commonly used as a "recovery drug" and taken toward the end of a steroid cycle.

Without a source this sounds odd. Clomifene works on the pituitary by interrupting the sex hormone-gonadotrope feedback loop. JFW | T@lk 11:39, 11 December 2005 (UTC)

The information posted is correct. Clomid is also a SERM (selective estrogen receptor modulator), which can prevent the growth of breast tissue in males who use anabolic steroids. Jrkarp 03:53, 15 December 2005 (UTC)

I know it's as SERM. I wrote this article and the SERM article :-) JFW | T@lk 08:57, 15 December 2005 (UTC)

Added 2 links and a small section on Side Effects User:Maggieliz 2-23-06

History???

I wish someone would say something about clomid's history and apparently, it has just always existed. No one discovered it. Does anyone know anything about it? Anything at all?

I purchaed serophene 100mg at on-line "Canadian Pharmacy" at http://directdrugensure.com with +1(650)452-6975 as helpline, and cost about $300. However the the shipping of the drug packet came to me was from India, and cames with no user instractions or any discription. The back of the drug packet labled as "CLOFI-100" it also has tiny small words says Clomifene Tables IP 100mg. They are lillte dark brown color pills. I searched the information on the Internet, many sites says it is "white" color. Could anyone tell me "what is the color of Colmifene"? Should I trust this drug from this on-line drag store? —Preceding unsigned comment added by 60.230.198.238 (talk) 13:51, 4 April 2010 (UTC)

Misc

In the table, under "legal status", it says "POD". What's that mean? I cannot find anything in Wikipedia under "POD" that seems to be related to pharmaceuticals. If it's a standard abbreviation, then it should be a link to a page describing it.

Do you mean "POM"? Could be "Prescription-Only Medication" ... Extenebris 17:10, 19 October 2006 (UTC)

IT MEANS PRESCRIPTION ONLY DRUG. —Preceding unsigned comment added by 117.212.46.29 (talk) 19:07, 27 April 2011 (UTC)

mode of action

It should be noted that clomifene has an effect on the hypothalamus as well- causing the hypothalamus to sense "low" levels of estrogen and therefor secrete GnRH in a higher frequency, which in turn causes a rise in gonadotropin release. It has an effect on the ovary and uterus as well.

Ormeloxifene main article needs editors

I've tried posting in Wikiproject:Clinical medicine, and have found few who know anything about ormeloxifene. Especially needed are chemists, scientists, and doctors who are knowledgable about this SERM. Thank you! Joie de Vivre 14:36, 14 December 2006 (UTC)

WP:LAME

Some anons keep on changing the spelling of "hot flashes" to "flushes" and back. If there was ever a silly edit war... But Googlefight (link) declares "hot flashes" unequivocal winner. JFW | T@lk 20:58, 12 April 2008 (UTC)

CURRENT Dx & Tx: OB&GYN uses "Hot Flushes" as the sub-chapter heading in symptoms of menopause, then uses "Hot Flahes" as a sub-chapter heading in differential diagnosis. CURRENT Medical Dx & Tx uses "Hot Flushes." Greenspan's Basic & Clinical Endocrinology uses "Hot Flashes." Williams Gynecology uses either/or. Goodman & Gilman's uses "hot flashes." Basic and Clinical Pharmacology uses "hot flushes." PubMed returns 2,518 hits for "hot flashes," and 1,464 hits for "hot flushes." Since it's a toss-up in the primary and secondary literature, and the Wikipedia page on the subject is already titled "hot flashes," it's probably best to leave it as "hot flashes" here, merely as a matter of internal consistency. Blahdenoma (talk) 07:05, 19 August 2011 (UTC)