Talk:Protein folding: Difference between revisions

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I'm not sure my biochemistry is up to it, but should something about the different levels of protein structure be added here, (primary, secondary, tertitary etc.)?

The main protein article has that - I suppose you could refer to that article. -- Marj 05:44, 26 Oct 2003 (UTC) ok

Folding temperature

I have read that the folding temperature of a protein is defined as the temperature at which there is a peak in the heat capacity of the protein. I am not sure what this means physically about what is different in the protein at the folding temperature versus below the folding temperature. However, I would like very much to know. Thank you.

The folding temperature is a minor point in the grand scheme of protein folding. FYI, it is a characteristic temperature at which the protein spends half the time in the folded state and half the time in the unfolded state. The peak of the heat capacity for any substance (protein or otherwise) is the temperature at which the transition from one state to another occurs (e.g. phase transition). So, for proteins, the peak is the temperature at which the protein goes from the unfolded state to the folded state.

external link to rosetta is needless- they do not study the protein folding. they predict final structure, ant this should be addressed to "protein structure prediction" . this also refers to human proteom folding project, predictor at home, fight aids at home and all others. only Stanford is studying the protein folding. 84.15.64.164 12:30, 8 May 2006 (UTC)Samurajus712[reply]

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 I have read that the folding temperature of a protein is defined as the temperature at which there is a peak in the heat capacity of the protein.  I am not sure what this means physically about what is different in the protein at the folding temperature versus below the folding temperature.  However, I would like very much to know.  Thank you.
-The folding temperature is a minor point in the grand scheme of protein folding.  FYI, it is a characteristic temperature at which the protein spends half the time in the folded state and half the time in the unfolded state.  The peak of the heat capacity for any substance (protein or otherwise) is the temperature at which the transition from one state to another occurs.  So, for proteins, the peak is the temperature at which the protein goes from the unfolded state to the folded state.
+The folding temperature is a minor point in the grand scheme of protein folding.  FYI, it is a characteristic temperature at which the protein spends half the time in the folded state and half the time in the unfolded state.  The peak of the heat capacity for any substance (protein or otherwise) is the temperature at which the transition from one state to another occurs (e.g. phase transition).  So, for proteins, the peak is the temperature at which the protein goes from the unfolded state to the folded state.
 ::external link to rosetta is needless- they do not study the protein folding. they predict final structure, ant this should be addressed to "[[protein structure prediction]]" . this also refers to human proteom folding project, predictor at home, fight aids at home and all others. only Stanford is studying the protein folding. [[User:84.15.64.164|84.15.64.164]] 12:30, 8 May 2006 (UTC)Samurajus712