ARHGEF1: Difference between revisions
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{{PBB|geneid=9138}} |
{{PBB|geneid=9138}} |
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'''Rho guanine nucleotide exchange factor 1''' is a [[protein]] that in humans is encoded by the ''ARHGEF1'' [[gene]].<ref name="pmid8810315">{{cite journal | author = Hart MJ, Sharma S, elMasry N, Qiu RG, McCabe P, Polakis P, Bollag G | title = Identification of a novel guanine nucleotide exchange factor for the Rho GTPase | journal = J Biol Chem | volume = 271 | issue = 41 | pages = 25452–8 | year = 1996 | month = Nov | pmid = 8810315 | pmc = | doi =10.1074/jbc.271.41.25452 }}</ref><ref name="pmid9135076">{{cite journal | author = Aasheim HC, Pedeutour F, Smeland EB | title = Characterization, expression and chromosomal localization of a human gene homologous to the mouse Lsc oncogene, with strongest expression in hematopoetic tissues | journal = Oncogene | volume = 14 | issue = 14 | pages = 1747–52 | year = 1997 | month = May | pmid = 9135076 | pmc = | doi = 10.1038/sj.onc.1200994 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9138| accessdate = }}</ref> |
'''Rho guanine nucleotide exchange factor 1''' is a [[protein]] that in humans is encoded by the ''ARHGEF1'' [[gene]].<ref name="pmid8810315">{{cite journal | author = Hart MJ, Sharma S, elMasry N, Qiu RG, McCabe P, Polakis P, Bollag G | title = Identification of a novel guanine nucleotide exchange factor for the Rho GTPase | journal = J Biol Chem | volume = 271 | issue = 41 | pages = 25452–8 | year = 1996 | month = Nov | pmid = 8810315 | pmc = | doi =10.1074/jbc.271.41.25452 }}</ref><ref name="pmid9135076">{{cite journal | author = Aasheim HC, Pedeutour F, Smeland EB | title = Characterization, expression and chromosomal localization of a human gene homologous to the mouse Lsc oncogene, with strongest expression in hematopoetic tissues | journal = Oncogene | volume = 14 | issue = 14 | pages = 1747–52 | year = 1997 | month = May | pmid = 9135076 | pmc = | doi = 10.1038/sj.onc.1200994 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9138| accessdate = }}</ref> |
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{{PBB_Summary |
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Revision as of 21:25, 17 December 2012
Template:PBB Rho guanine nucleotide exchange factor 1 is a protein that in humans is encoded by the ARHGEF1 gene.[1][2][3]
Interactions
ARHGEF1 has been shown to interact with GNA13,[4][5][6] CD44,[4] P110α[7] and GNA12.[4]
References
- ^ Hart MJ, Sharma S, elMasry N, Qiu RG, McCabe P, Polakis P, Bollag G (1996). "Identification of a novel guanine nucleotide exchange factor for the Rho GTPase". J Biol Chem. 271 (41): 25452–8. doi:10.1074/jbc.271.41.25452. PMID 8810315.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link) - ^ Aasheim HC, Pedeutour F, Smeland EB (1997). "Characterization, expression and chromosomal localization of a human gene homologous to the mouse Lsc oncogene, with strongest expression in hematopoetic tissues". Oncogene. 14 (14): 1747–52. doi:10.1038/sj.onc.1200994. PMID 9135076.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ "Entrez Gene: ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1".
- ^ a b c
- ^ Bhattacharyya, Raja (2003). "Mutation of an N-terminal acidic-rich region of p115-RhoGEF dissociates alpha13 binding and alpha13-promoted plasma membrane recruitment". FEBS Lett. 540 (1–3). Netherlands: 211–6. doi:10.1016/S0014-5793(03)00267-9. ISSN 0014-5793. PMID 12681510.
{{cite journal}}: Unknown parameter|coauthors=ignored (|author=suggested) (help); Unknown parameter|month=ignored (help) - ^ Hart, M J (1998). "Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13". Science. 280 (5372). UNITED STATES: 2112–4. doi:10.1126/science.280.5372.2112. ISSN 0036-8075. PMID 9641916.
{{cite journal}}: Unknown parameter|coauthors=ignored (|author=suggested) (help); Unknown parameter|month=ignored (help) - ^ Holinstat, Michael (2003). "Protein kinase Calpha-induced p115RhoGEF phosphorylation signals endothelial cytoskeletal rearrangement". J. Biol. Chem. 278 (31). United States: 28793–8. doi:10.1074/jbc.M303900200. ISSN 0021-9258. PMID 12754211.
{{cite journal}}: Unknown parameter|coauthors=ignored (|author=suggested) (help); Unknown parameter|month=ignored (help)CS1 maint: unflagged free DOI (link)
Further reading
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