AMPA

For the degradation product of glyphosphate also known as AMPA, see aminomethylphosphonic acid.

For the U.S. LGBT advocacy and support group, see The American Military Partner Association.

AMPA

Names
IUPAC name 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic acid
Identifiers
CAS Number	77521-29-0 N
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL276815 N
ChemSpider	1184 Y
DrugBank	DB02057 Y
KEGG	C11033 Y
MeSH	AMPA
PubChem CID	1221
CompTox Dashboard (EPA)	DTXSID20868301
InChI InChI=1S/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12) Y Key: UUDAMDVQRQNNHZ-UHFFFAOYSA-N Y InChI=1/C7H10N2O4/c1-3-4(6(10)9-13-3)2-5(8)7(11)12/h5H,2,8H2,1H3,(H,9,10)(H,11,12) Key: UUDAMDVQRQNNHZ-UHFFFAOYAT
SMILES O=C1/C(=C(\ON1)C)CC(N)C(=O)O
Properties
Chemical formula	C7H10N2O4
Molar mass	186.17 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

AMPA (2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic acid) is a compound that is a specific agonist for the AMPA receptor, where it mimics the effects of the neurotransmitter glutamate.

There are two types of Ionotropic glutamate receptors that are ligand gated ion channels whose agonists include AMPA, kainic acid and N-methyl-D-aspartic acid (NMDA). In the synapse, these two classes of receptors serve very different purposes. AMPA can be used experimentally to distinguish the activity of one receptor from the other in order to understand their differing functions. AMPA generates fast excitatory postsynaptic potentials (EPSP). AMPA activates AMPA receptors that are non-selective cationic channels allowing the passage of Na⁺ and K⁺ and therefore have an equilibrium potential near 0 mV.