Immunophilins: Difference between revisions
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* [http://pmb.berkeley.edu/faculty/faculty_pages/Luan.html "Plant immunophilins and signal transduction"] at berkeley.edu |
* [http://pmb.berkeley.edu/faculty/faculty_pages/Luan.html "Plant immunophilins and signal transduction"] at berkeley.edu |
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[[ca:Immunofilina]] |
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Revision as of 03:51, 1 March 2013
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In molecular biology, immunophilins are endogenous cytosolic peptidyl-prolyl isomerases that interconvert [sic] between the cis and trans positions.
Immunophilins are targeted by immunosuppressive drugs such as rapamycin, cyclosporine, and tacrolimus. For these drugs in particular, known immunophilins such as cyclophilin catalyze the cis-trans isomerization of peptide bonds, particularly X-Pro peptide bonds. This isomerase activity can be inhibited by immunosuppressive drugs.
See also
External links
- Immunophilins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- "Plant immunophilins and signal transduction" at berkeley.edu
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 | This immunology article is a stub. You can help Wikipedia by expanding it. |