Jump to content

Quinethazone: Difference between revisions

From Wikipedia, the free encyclopedia
Content deleted Content added
CheMoBot (talk | contribs)
Updating {{drugbox}} (no changed fields - added verified revid - updated 'ChEBI_Ref') per Chem/Drugbox validation (report errors or bugs)
No edit summary
Line 52: Line 52:
| StdInChIKey = AGMMTXLNIQSRCG-UHFFFAOYSA-N
| StdInChIKey = AGMMTXLNIQSRCG-UHFFFAOYSA-N
}}
}}
'''Quinethazone''' ([[International Nonproprietary Name|INN]], brand name '''Hydromox''') is a [[thiazide]] [[diuretic]] used to treat [[hypertension]]. Common side effects include [[dizziness]], dry mouth, [[nausea]], and [[hypokalemia|low potassium]] levels.
'''Quinethazone''' ([[International Nonproprietary Name|INN]], brand name '''Hydromox''') is a [[thiazide-like]] [[diuretic]] used to treat [[hypertension]]. Common side effects include [[dizziness]], dry mouth, [[nausea]], and [[hypokalemia|low potassium]] levels.


==Synthesis==
==Synthesis==

Revision as of 00:51, 31 October 2013

Quinethazone
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 7-chloro-2-ethyl-4-oxo-1,2,3,4-tetrahydroquinazoline-
    6-sulfonamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.000.729 Edit this at Wikidata
Chemical and physical data
FormulaC10H12ClN3O3S
Molar mass289.739 g/mol g·mol−1
3D model (JSmol)
  • O=S(=O)(c2c(Cl)cc1c(C(=O)NC(N1)CC)c2)N
  • InChI=1S/C10H12ClN3O3S/c1-2-9-13-7-4-6(11)8(18(12,16)17)3-5(7)10(15)14-9/h3-4,9,13H,2H2,1H3,(H,14,15)(H2,12,16,17) checkY
  • Key:AGMMTXLNIQSRCG-UHFFFAOYSA-N checkY
  (verify)

Quinethazone (INN, brand name Hydromox) is a thiazide-like diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.

Synthesis

References

Cohen, Elliott; Klarberg, Betty; Vaughan, James R. (1960). Journal of the American Chemical Society. 82 (11): 2731. doi:10.1021/ja01496a020. {{cite journal}}: Missing or empty |title= (help)