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'''neuGRID''' is a web portal aimed to (i) help [[neuroscientist]]s do high-throughput [[Magnetic resonance imaging|imaging]] research, and (ii) provide clinical neurologists automated diagnostic imaging markers of neurodegenerative diseases for individual patient diagnosis. neuGRID’s user-friendly environment is customised to a range of users from students to senior neuroscientists working in the fields of [[Alzheimer’s disease]], [[psychiatric diseases]], and [[white matter diseases]]. neuGRID aims to become a widespread resource for brain imaging analyses.
'''neuGRID''' is a web portal aimed to (i) help [[neuroscientist]]s do high-throughput [[Magnetic resonance imaging|imaging]] research, and (ii) provide clinical neurologists automated diagnostic imaging markers of neurodegenerative diseases for individual patient diagnosis. neuGRID’s user-friendly environment is customised to a range of users from students to senior neuroscientists working in the fields of [[Alzheimer’s disease]], [[psychiatric diseases]], and [[white matter diseases]]. neuGRID aims to become a widespread resource for brain imaging analyses.


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== Publications ==
== Publications ==
''On the infrastructure''
===On the infrastructure===
*{{cite journal |doi=10.1038/nrneurol.2011.99}}
* Frisoni GB, Redolfi A, Manset D, Rousseau MÉ, Toga A, Evans AC. [http://www.ncbi.nlm.nih.gov/pubmed/?term=Virtual+imaging+laboratories+for+marker+discovery+in+neurodegenerative+diseases. Virtual imaging laboratories for marker discovery in neurodegenerative diseases.] Nat Rev Neurol 2011; 7: 429-38.
*{{cite journal |doi=10.2217/fnl.09.53}}
* Redolfi A, McClatchey R, Anjum A, Zijdenbos A, Manset D, Barkhof F, Spenger C, Legré Y, Wahlund L, Barattieri di San Pietro C, Frisoni GB. [http://www.futuremedicine.com/doi/abs/10.2217/fnl.09.53 Grid infrastructures for computational neuroscience: the neuGRID example.] Future Neurology 2009; 4: 703-22.
*{{cite journal |pmid=22427183}}
* Barkhof F. [http://www.ncbi.nlm.nih.gov/pubmed/22427183 Making better use of our brain MRI research data.] Eur Radiol 2012; 22: 1395-6.
*{{cite journal |pmid=19593068 |url=http://booksonline.iospress.nl/Extern/EnterMedLine.aspx?ISSN=0926-9630&Volume=147&SPage=283}}
* Anjum A, Bloodsworth P, Habib I, Lansdale T, McClatchey R, Mehmood Y; neuGRID Consortium. [http://www.ncbi.nlm.nih.gov/pubmed/?term=Reusable+services+from+the+neuGRID+project+for+grid-based+health+applications. Reusable services from the neuGRID project for grid-based health applications.] Stud Health Technol Inform 2009; 147: 283-8.


''Neuroscientific studies where neuGRID has been used as a resource''
===Neuroscientific studies where neuGRID has been used as a resource===
*{{cite journal |doi=10.11138/FNeur/2013.28.3.175}}
* Redolfi A, Bosco P, Manset D, Frisoni GB, neuGRID Consortium. [http://www.functionalneurology.com/common/php/portiere.php?ID=3a2bb5a649fcf9deb9cba71695f4a4d9 Brain investigation and brain conceptualization.] Functional Neurology; 2013; Vol.28(3): 175-190.
*{{cite journal |doi=10.1016/j.pscychresns.2011.02.012}}
* Cover KS, van Schijndel RA, van Dijk BW, Redolfi A, Knol DL, Frisoni GB, Barkhof F, Vrenken H; neuGRID Consortium; Alzheimer's Disease Neuroimaging Initiative. [http://www.ncbi.nlm.nih.gov/pubmed/?term=Alzheimer's+Disease+Neuroimaging+Initiative.+Assessing+the+reproducibility+of+the+SienaX+and+Siena+brain Assessing the reproducibility of the SienaX and Siena brain atrophy measures using the ADNI back-to-back MP-RAGE MRI scans.] Psychiatry Res 2011; 193: 182-90.
*{{cite journal |pmid=20139996}}
* Frisoni GB, Fox N, Jack C Jr, Scheltens P, and Thompson PM. [http://www.ncbi.nlm.nih.gov/pubmed/20139996 The clinical use of structural MRI in Alzheimer disease]. Nat Rev Neurol; 2010; 6:67–77.


== External links ==
== External links ==

Revision as of 13:13, 2 February 2014

NeuGRID
NeuGRID logo
URLneugrid4you.eu
Current statusActive

neuGRID is a web portal aimed to (i) help neuroscientists do high-throughput imaging research, and (ii) provide clinical neurologists automated diagnostic imaging markers of neurodegenerative diseases for individual patient diagnosis. neuGRID’s user-friendly environment is customised to a range of users from students to senior neuroscientists working in the fields of Alzheimer’s disease, psychiatric diseases, and white matter diseases. neuGRID aims to become a widespread resource for brain imaging analyses.

Process

Through the single virtual access point Science Gateway web portal, users login and access a “virtual” imaging laboratory. Here users can upload, use, and share algorithms for brain imaging analysis, have access to large neuroimaging datasets, and make computationally intensive analyses, all the time with specialized support and training. Thanks to distributed services and grid/cloud computational resources, analyses with neuGRID are much faster than traditional-style lab-based analyses. neuGRID’s proof-of-concept was carried out in 2009 when an Alzheimer's disease biomarker (3D cortical thickness with Freesurfer and CIVET) was extracted from 6.500 MR scans in 2 weeks versus 5 years that it would have taken in a traditional setting.

History

neuGRID was first funded by the European Commission DG INFSO within the 7th Framework Program from 2008 to 2011. Here, the hardware and middleware infrastructure were developed. The second wave was funded in 2011 by the European Commission, now DG CONNECT, under the project neuGRID for you (N4U), with the main aim of expanding user services with more intuitive and graphical interfaces. N4U will end in December 2014.

Consortium

The initial neuGRID consortium involved 8 European partners from Italy, France, UK, Nederland, Sweden, Spain and Switzerland. N4U involves 9 European partners (6 of which already in neuGRID) and 2 North Americans. International partners have been involved thanks to a support action funded once more by DG INFSO (outGRID, http://www.outgrid.eu). The coordinator of all three projects is Giovanni B Frisoni, neurologist based at the IRCCS Fatebenefratelli, The National Centre for Alzheimer’s Disease in Brescia, Italy.

Publications

On the infrastructure

  • . doi:10.1038/nrneurol.2011.99. {{cite journal}}: Cite journal requires |journal= (help); Missing or empty |title= (help)
  • . doi:10.2217/fnl.09.53. {{cite journal}}: Cite journal requires |journal= (help); Missing or empty |title= (help)
  • . PMID 22427183. {{cite journal}}: Cite journal requires |journal= (help); Missing or empty |title= (help)
  • . PMID 19593068 http://booksonline.iospress.nl/Extern/EnterMedLine.aspx?ISSN=0926-9630&Volume=147&SPage=283. {{cite journal}}: Cite journal requires |journal= (help); Missing or empty |title= (help)

Neuroscientific studies where neuGRID has been used as a resource